Neptune Ice

Manufacturer: A-S Medication Solutions
Effective date: 2021-06-14
Label type: HUMAN OTC DRUG LABEL
Version: 3
Source: full-release
Hydrated at: 2026-05-31 23:40:49

Label at a glance#

ProductNeptune Ice

Active ingredientCAMPHOR (NATURAL), DIMETHICONE, LIDOCAINE, MENTHOL

Label structure16 sections

Indications and uses

For the temporary relief of joint pain and muscle pain associated with: Arthritis Backache Discomfort Cramps Neckache Soreness Sprains Strains

Dosage and administration

Ad ults and Children 12 years of Age and Older: Clean and dry the affected area Apply product directly to your skin, up to 4 times daily

Contacts and useful links#

PhoneLabel contact(877) 985-8377

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Methemoglobinemia

Cases of methemoglobinemia have been reported in association with local anesthetic use. Although all patients are at risk for methemoglobinemia, patients with glucose-6-phosphate dehydrogenase deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary compromise, infants under 6 months of age, and concurrent exposure to oxidizing agents or their metabolites are more susceptible to developing clinical manifestations of the condition. If local anesthetics must be used in these patients, close monitoring for symptoms and signs of methemoglobinemia is recommended.

Signs and symptoms of methemoglobinemia may occur immediately or may be delayed some hours after exposure and are characterized by a cyanotic skin discoloration and abnormal coloration of the blood. Methemoglobin levels may continue to rise; therefore, immediate treatment is required to avert more serious central nervous system and cardiovascular adverse effects, including seizures, coma, arrhythmias, and death. Discontinue lidocaine-containing products and any other oxidizing agents. Depending on the severity of the symptoms, patients may respond to supportive care, i.e., oxygen therapy, hydration. More severe symptoms may require treatment with methylene blue, exchange transfusion, or hyperbaric oxygen

Active Ingredient

OTC - ACTIVE INGREDIENT SECTION

Lidocaine 4%

Purpose

OTC - PURPOSE SECTION

Topical Anesthetic

Active Ingredient

OTC - ACTIVE INGREDIENT SECTION

Menthol 1%

Purpose

OTC - PURPOSE SECTION

Topical Analgesic

Active Ingredient

OTC - ACTIVE INGREDIENT SECTION

Camphor 3%

Purpose

OTC - PURPOSE SECTION

Topical Analgesic

Active Ingredient

OTC - ACTIVE INGREDIENT SECTION

Dimethicone 3%

Purpose

OTC - PURPOSE SECTION

Skin Conditioner

Uses:

INDICATIONS & USAGE SECTION

For the temporary relief of joint pain and muscle pain associated with:

Arthritis
Backache
Discomfort
Cramps
Neckache
Soreness
Sprains
Strains

Warnings

WARNINGS SECTION

For External Use Only

Flammable

SPL UNCLASSIFIED SECTION

Keep away from excessive heat or open flame

Do Not Use

OTC - DO NOT USE SECTION

On damaged or irritated skin
With a bandage or heating pad
If you are allergic to any ingredients in this product
Other than as directed

When Using This Product

OTC - WHEN USING SECTION

Avoid contact with the eyes

Stop Use and Ask a Doctor If

OTC - ASK DOCTOR SECTION

Condition worsens
Excessive skin irritation develops
Symptoms persist for more than 7 days, or symptoms clear up and occur again within 3 days

If You Are Pregnant or Breast Feeding

OTC - PREGNANCY OR BREAST FEEDING SECTION

Ask a health professional before use

Keep Out of Reach of Children

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

If ingested, seek medical help or contact a Poison Control Center immediately

Directions

DOSAGE & ADMINISTRATION SECTION

Adults and Children 12 years of Age and Older:

Clean and dry the affected area
Apply product directly to your skin, up to 4 times daily

Other Information

SPL UNCLASSIFIED SECTION

Store in a cool, dry place with lid tightly closed

Inactive Ingredients

INACTIVE INGREDIENT SECTION

Aloe Barbadensis Leaf Juice, Arnica Montana Flower, Boswellia Serrata Extract, Carbomer, Ethylhexylglycerin, FD&C Blue #1, Methylsulfonylmethane, Phenoxyethanol, Polysorbate 20, SD-Alcohol 40B, Sorbitol, Triethanolamine, Water.

Questions or Comments?

OTC - QUESTIONS SECTION

(877) 985-8377

HOW SUPPLIED

HOW SUPPLIED SECTION

Product: 50090-4640

NDC: 50090-4640-0 89 mL in a TUBE, WITH APPLICATOR

Lidocaine, Menthol, Camphor, and Dimethicone Gel

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
2186001	camphor 3 % / dimethicone 3 % / lidocaine 4 % / menthol 1 % Topical Gel	PSN	3
2186001	camphor 0.03 MG/MG / dimethicone 0.03 MG/MG / lidocaine 0.04 MG/MG / menthol 0.01 MG/MG Topical Gel	SCD	3
2186001	camphor 3 % / dimethicone 3 % / lidocaine 4 % / menthol 1 % Topical Gel	SY	3

DailyMed Pharmacologic Classes#

Class, Version, Type table
Class	Version	Type	Effective
DIMETHICONE Pharmacologic Class Indexing	3	Indexing - Pharmacologic Class	20180813
LIDOCAINE Pharmacologic Class Indexing	2	Indexing - Pharmacologic Class	20180813

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
50090-4640-0	2023-01-30	C162847	48780-1	f386c649-e8e9-0266-e053-dadaa90a7c1a	Neptune Ice

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
50090-4640-0	Neptune Ice	89 mL in 1 TUBE, WITH APPLICATOR	GEL	89		3

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
50090-4640	NEPTUNE ICE (LIDOCAINE, MENTHOL, CAMPHOR, AND DIMETHICONE) GEL [A-S MEDICATION SOLUTIONS]	3	Legacy NDC, 1 package rows	20210615_e7877b23-17d6-4484-86a0-4123efacf2d2.zip

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
72594-1846-8	GM - Gram	72594-1846	7ee52ed6-61c3-409d-9887-d0afcf176fcc	1	2019-08-06

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 19 matching rows.

Neptune Ice
Lidocaine, Menthol, Camphor, and Dimethicone
ALOE VERA LEAF
POLYSORBATE 20
FD&C BLUE NO. 1
ETHYLHEXYLGLYCERIN
ARNICA MONTANA FLOWER
PHENOXYETHANOL
CARBOXYPOLYMETHYLENE
INDIAN FRANKINCENSE OIL
WATER
DIMETHYL SULFONE
ALCOHOL
TROLAMINE
SORBITOL
CAMPHOR (NATURAL)
DIMETHICONE
LIDOCAINE
MENTHOL

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
50090-4640	50090-4640-0
72594-1846

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 17 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
ALOE VERA LEAF	ZY81Z83H0X	IACT
POLYSORBATE 20	7T1F30V5YH	IACT
FD&C BLUE NO. 1	H3R47K3TBD	IACT
ETHYLHEXYLGLYCERIN	147D247K3P	IACT
ARNICA MONTANA FLOWER	OZ0E5Y15PZ	IACT
PHENOXYETHANOL	HIE492ZZ3T	IACT
CARBOXYPOLYMETHYLENE	0A5MM307FC	IACT
INDIAN FRANKINCENSE OIL	5T1XCE6K8K	IACT
WATER	059QF0KO0R	IACT
DIMETHYL SULFONE	9H4PO4Z4FT	IACT
ALCOHOL	3K9958V90M	IACT
TROLAMINE	9O3K93S3TK	IACT
SORBITOL	506T60A25R	IACT
CAMPHOR (NATURAL)	N20HL7Q941	ACTIB
DIMETHICONE	92RU3N3Y1O	ACTIB
LIDOCAINE	98PI200987	ACTIB
MENTHOL	L7T10EIP3A	ACTIB

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
accec53c-ad9c-4a26-a776-1e3065f4a867			e7877b23-17d6-4484-86a0-4123efacf2d2	2021-06-14	Warnings	Exact identifier spl id: accec53c-ad9c-4a26-a776-1e3065f4a867 spl set id: e7877b23-17d6-4484-86a0-4123efacf2d2

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.