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warnings
WARNINGS Ephedrine may cause hypertension resulting in intracranial hemorrhage. Ephedrine may induce anginal pain in patients with coronary insufficiency or ischemic heart disease. The drug also may induce potentially fatal arrhythmias in patients with organic heart disease or who are receiving drugs that sensitize the myocardium. See CONTRAINDICATIONS . Initially, parenterally administered ephedrine may produce constriction of renal blood vessels and decreased urine formation.
ADVERSE REACTIONS Acute toxic effects are usually extensions of the therapeutic actions of the drug and are most often due to overdosage. Excessive doses may cause a sharp rise in blood pressure sufficient to produce cerebral hemorrhage. Other effects (usually transient) include headache, restlessness, anxiety, tension, tremor, weakness, dizziness, confusion, delirium hallucinations, pallor, respiratory difficulty, palpitation, sweating, nausea or vomiting. Repeated injections may cause contraction of the bladder sphincter and interfere with voluntary urination. The possibility of urinary retention, especially in the elderly male, should be kept in mind.