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warnings
WARNINGS Excessive use of adrenergic aerosols is potentially dangerous. Fatalities have been reported following excessive use of metaproterenol sulfate as with other sympathomimetic inhalation preparations, and the exact cause is unknown. Cardiac arrest was noted in several cases. Paradoxical bronchoconstriction with repeated excessive administration has been reported with sympathomimetic agents. Patients should be advised to contact their physician in the event that they do not respond to their usual dose of sympathomimetic amine aerosol.
ADVERSE REACTIONS Adverse reactions are similar to those noted with other sympathomimetic agents. The most frequent adverse reactions to metaproterenol sulfate are nervousness and tachycardia which occur in about 1 in 7 patients, tremor which occurs in about 1 in 20 patients, and nausea which occurs in about 1 in 50 patients. Less frequent adverse reactions are hypertension, palpitations, vomiting and bad taste which occur in approximately 1 in 300 patients.