EVOTAZ

Product NDC
0003-3641
11-digit product format
000033641
Labeler code
0003
Product ID
0003-3641_fa642c67-5a9e-4136-a141-64e1236f6a0f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
atazanavir and cobicistat
Dosage form
TABLET
Route
ORAL
Labeler
E.R. Squibb & Sons, L.L.C.
Application
NDA206353
Marketing category
NDA
Marketing start
2015-01-29
Substance
ATAZANAVIR SULFATE; COBICISTAT
Active strength
300; 150 mg/1; mg/1
Pharmacologic classes
Breast Cancer Resistance Protein Inhibitors [MoA], Cytochrome P450 2C8 Inhibitors [MoA], Cytochrome P450 2D6 Inhibitors [MoA], Cytochrome P450 3A Inhibitor [EPC], Cytochrome P450 3A Inhibitors [MoA], Cytochrome P450 3A Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], HIV Protease Inhibitors [MoA], Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA], Organic Anion Transporting Polypeptide 1B1 Inhibitors [MoA], Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA], Protease Inhibitor [EPC], UDP Glucuronosyltransferases Inhibitors [MoA], UGT1A1 Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N206353-001EVOTAZATAZANAVIR SULFATE; COBICISTATEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29

Orange Book patents#

Current patent rows page 1 of 1 · 2 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25
N206353-001100397182032-10-06Drug product2018-09-05

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-2931067a03dcf5…
2025-08-23 18:47 UTC2025-08N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-296a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-2903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-292680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-295bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-2979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-291e350fbaab3a…
2024-05-31 18:47 UTC2024-05N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-298072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-295c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-295d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-294b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-2974a2ff9319b5…
2022-03-09 01:35 UTC2022-03N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-2987673890dc5c…
2021-03-12 10:30 UTC2021-03N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-295aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-298869cabd3fbd…
2020-11-12 02:37 UTC2020-11N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29c0c555d07b60…
2019-12-14 00:12 UTC2019-12N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-293f01610625f2…
2019-09-15 20:21 UTC2019-09N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29b00525d2431f…
2019-07-19 19:46 UTC2019-07N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-296a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-291c564ffb4f44…
2023-12-20 04:57 UTC2023-12N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-299b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-293f0d92c62455…
2023-05-13 08:27 UTC2023-05N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29053a50430f4f…
2023-01-26 05:58 UTC2023-01N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-293bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-293a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N206353-001EVOTAZEQ 300MG BASE;150MGTABLET / ORALRLD, RS2015-01-29cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 3 · 86 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N206353-001100397182032-10-06Drug product2018-09-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N206353-001100397182032-10-06Drug product2018-09-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N206353-001100397182032-10-06Drug product2018-09-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N206353-001100397182032-10-06Drug product2018-09-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N206353-001100397182032-10-06Drug product2018-09-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N206353-001100397182032-10-06Drug product2018-09-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N206353-001100397182032-10-06Drug product2018-09-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N206353-001100397182032-10-06Drug product2018-09-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N206353-001100397182032-10-06Drug product2018-09-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25d06236e962d9…
2024-10-29 15:01 UTC2024-10N206353-001100397182032-10-06Drug product2018-09-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N206353-001100397182032-10-06Drug product2018-09-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N206353-001100397182032-10-06Drug product2018-09-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N206353-001100397182032-10-06Drug product2018-09-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-258072bd15b7f6…
2024-05-31 18:47 UTC2024-05N206353-001100397182032-10-06Drug product2018-09-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-255c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N206353-001100397182032-10-06Drug product2018-09-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-255d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N206353-001100397182032-10-06Drug product2018-09-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-254b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N206353-001100397182032-10-06Drug product2018-09-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N206353-0016087383*PED2019-06-21Pediatric extension74a2ff9319b5…
2019-12-13 00:20 UTC2019-12N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-2574a2ff9319b5…
2019-12-13 00:20 UTC2019-12N206353-001100397182032-10-04Drug product2018-09-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N206353-001100397182032-10-06Drug product2018-09-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N206353-00181483742029-09-03U-1279Drug substance, Drug product2015-02-25782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
EVOTAZ
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ATAZANAVIR SULFATE300 mg/1
COBICISTAT150 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4MT4VIE29PInternal UNII lookup
LW2E03M5PGInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1601654Internal RxNorm lookup
1601660Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
83db29d7-5d85-49d6-8cb6-740473365cf8Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
81157882-d7f5-4b49-9a52-b2a0c7e54020Product name220260107
7bc938bd-f454-36ec-72ed-9ef05424b276Product name820221117
a56d673d-fa42-4b0e-b5ce-e65a5eab34b7Product name120180911
7fd46899-3505-4ed4-b856-6b2509a76004Product name120151123
8abcd50f-6149-4309-942e-836623ca381dProduct name120150401
248d7995-abf1-4569-b3c6-f9ebc230e8efProduct name120150323
0583b5e6-2e6e-c94b-9ff6-81a81ba199deProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0003-3641-11EVOTAZ30 in 1 BOTTLETABLET3016

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0003-3641-11EA - Each0003-3641ac733342-64b3-4f0b-a025-97e05e26455c12015-03-03

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0003-3641EVOTAZ (ATAZANAVIR AND COBICISTAT) TABLET [E.R. SQUIBB & SONS, L.L.C.]16Current NDC, Legacy NDC, 1 package rows20250524_83db29d7-5d85-49d6-8cb6-740473365cf8.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EVOTAZATAZANAVIR AND COBICISTATE.R. Squibb & Sons, L.L.C.83db29d7-5d85-49d6-8cb6-740473365cf82025-05-12Warnings, Adverse reactionsExact identifier
application applno (NDA): 206353
application number: NDA206353
ndc (product): 0003-3641

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1601654atazanavir 300 MG / cobicistat 150 MG Oral TabletPSN83db29d7-5d85-49d6-8cb6-740473365cf816
1601660EVOTAZ 300 MG / 150 MG Oral TabletPSN83db29d7-5d85-49d6-8cb6-740473365cf816
1601660atazanavir 300 MG / cobicistat 150 MG Oral Tablet [Evotaz]SBD83db29d7-5d85-49d6-8cb6-740473365cf816
1601654atazanavir 300 MG / cobicistat 150 MG Oral TabletSCD83db29d7-5d85-49d6-8cb6-740473365cf816
1601660Evotaz (atazanavir 300 MG (as atazanavir sulfate 342 MG) / cobicistat 150 MG) Oral TabletSY83db29d7-5d85-49d6-8cb6-740473365cf816

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0003-3641-110000336411130 TABLET in 1 BOTTLE (0003-3641-11) 30 tablet2015-01-290000-00-00NoNoCurrent