EMEND

Product NDC
0006-3066
11-digit product format
000063066
Labeler code
0006
Product ID
0006-3066_428f7828-6d1c-438b-a17d-b4af0700c740
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
aprepitant
Dosage form
POWDER, FOR SUSPENSION
Route
ORAL
Labeler
Merck Sharp & Dohme LLC
Application
NDA207865
Marketing category
NDA
Marketing start
2015-12-17
Substance
APREPITANT
Active strength
125 mg/1
Pharmacologic classes
Cytochrome P450 2C9 Inducers [MoA], Cytochrome P450 3A4 Inducers [MoA], Cytochrome P450 3A4 Inhibitors [MoA], Neurokinin 1 Antagonists [MoA], Substance P/Neurokinin-1 Receptor Antagonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N207865-001EMENDAPREPITANT125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17

Orange Book patents#

Current patent rows page 1 of 1 · 1 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N207865-00182581322027-09-26U-1916Drug product2016-11-18

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-1731067a03dcf5…
2025-08-23 18:47 UTC2025-08N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-176a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-1703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-172680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-175bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-1779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-171e350fbaab3a…
2024-05-31 18:47 UTC2024-05N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-178072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-175c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-175d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-174b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-1774a2ff9319b5…
2022-03-09 01:35 UTC2022-03N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-1787673890dc5c…
2021-03-12 10:30 UTC2021-03N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-175aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-178869cabd3fbd…
2020-11-12 02:37 UTC2020-11N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17c0c555d07b60…
2019-12-14 00:12 UTC2019-12N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-173f01610625f2…
2019-09-15 20:21 UTC2019-09N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17b00525d2431f…
2019-07-19 19:46 UTC2019-07N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-176a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-171c564ffb4f44…
2023-12-20 04:57 UTC2023-12N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-179b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-173f0d92c62455…
2023-05-13 08:27 UTC2023-05N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17053a50430f4f…
2023-01-26 05:58 UTC2023-01N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-173bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-173a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N207865-001EMEND125MG/KITFOR SUSPENSION / ORALRLD, RS2015-12-17e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N207865-00182581322027-09-26U-1916Drug product2016-11-18caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N207865-00182581322027-09-26U-1916Drug product2016-11-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N207865-00182581322027-09-26U-1916Drug product2016-11-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08N207865-00182581322027-09-26U-1916Drug product2016-11-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N207865-00182581322027-09-26U-1916Drug product2016-11-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N207865-00182581322027-09-26U-1916Drug product2016-11-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N207865-00182581322027-09-26U-1916Drug product2016-11-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N207865-00182581322027-09-26U-1916Drug product2016-11-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N207865-00182581322027-09-26U-1916Drug product2016-11-185bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N207865-00182581322027-09-26U-1916Drug product2016-11-18d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N207865-00182581322027-09-26U-1916Drug product2016-11-18d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N207865-00182581322027-09-26U-1916Drug product2016-11-1879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N207865-00182581322027-09-26U-1916Drug product2016-11-18301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N207865-00182581322027-09-26U-1916Drug product2016-11-181e350fbaab3a…
2024-05-31 18:47 UTC2024-05N207865-00182581322027-09-26U-1916Drug product2016-11-188072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N207865-00182581322027-09-26U-1916Drug product2016-11-185c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N207865-00182581322027-09-26U-1916Drug product2016-11-185d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N207865-00182581322027-09-26U-1916Drug product2016-11-184b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N207865-00182581322027-09-26U-1916Drug product2016-11-1874a2ff9319b5…
2022-03-09 01:35 UTC2022-03N207865-00182581322027-09-26U-1916Drug product2016-11-18bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N207865-00182581322027-09-26U-1916Drug product2016-11-18782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N207865-00182581322027-09-26U-1916Drug product2016-11-1887673890dc5c…
2021-03-12 10:30 UTC2021-03N207865-00182581322027-09-26U-1916Drug product2016-11-185aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N207865-00182581322027-09-26U-1916Drug product2016-11-188869cabd3fbd…
2020-11-12 02:37 UTC2020-11N207865-00182581322027-09-26U-1916Drug product2016-11-18c0c555d07b60…
2019-12-14 00:12 UTC2019-12N207865-00182581322027-09-26U-1916Drug product2016-11-183f01610625f2…
2019-09-15 20:21 UTC2019-09N207865-00182581322027-09-26U-1916Drug product2016-11-18b00525d2431f…
2019-07-19 19:46 UTC2019-07N207865-00182581322027-09-26U-1916Drug product2016-11-18ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N207865-00182581322027-09-26U-1916Drug product2016-11-186a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N207865-00182581322027-09-26U-1916Drug product2016-11-181c564ffb4f44…
2023-12-20 04:57 UTC2023-12N207865-00182581322027-09-26U-1916Drug product2016-11-18ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N207865-00182581322027-09-26U-1916Drug product2016-11-18a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N207865-00182581322027-09-26U-1916Drug product2016-11-189b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N207865-00182581322027-09-26U-1916Drug product2016-11-18a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N207865-00182581322027-09-26U-1916Drug product2016-11-183f0d92c62455…
2023-05-13 08:27 UTC2023-05N207865-00182581322027-09-26U-1916Drug product2016-11-18053a50430f4f…
2023-01-26 05:58 UTC2023-01N207865-00182581322027-09-26U-1916Drug product2016-11-183bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N207865-00182581322027-09-26U-1916Drug product2016-11-183a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N207865-00182581322027-09-26U-1916Drug product2016-11-18f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N207865-00182581322027-09-26U-1916Drug product2016-11-18e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
EMEND
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
APREPITANT125 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1NF15YR6UYInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 10 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
403810Internal RxNorm lookup
403811Internal RxNorm lookup
404465Internal RxNorm lookup
404466Internal RxNorm lookup
644088Internal RxNorm lookup
644278Internal RxNorm lookup
754508Internal RxNorm lookup
754509Internal RxNorm lookup
1729308Internal RxNorm lookup
1729311Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
696f9e80-9cae-403b-de9e-078343ce4713Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2abc3e32-ae1f-4dec-be1c-0c39ac95b38eProduct name720240514
5d352eda-d4de-4572-9a3f-32d6fd204f9aProduct name120230911
3a5d67cc-4a03-45a3-8d74-5aeb67631be4Product name120230831
85fc66a9-58b2-e194-7cdb-89ff44dcf3e6Product name420210518
9f9a82fd-fcee-442f-9233-7f2d2f9f4568Product name120180108

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0006-3066-01EMEND1 in 1 POUCHPOWDER, FOR SUSPENSION142
0006-3066-03EMEND1 in 1 CARTONPOWDER, FOR SUSPENSION142

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0006-3066-01EA - Each0006-306660c9f75a-caba-4f6e-be9a-de5af7b2e5fe12018-04-19
0006-3066-03EA - Each0006-30662e8c3ba6-94e7-4874-9e7a-471e8694639112016-08-09

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0006-3066EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT EMEND (APREPITANT) POWDER, FOR SUSPENSION [MERCK SHARP & DOHME LLC]41Current NDC, Legacy NDC, 2 package rows20240719_696f9e80-9cae-403b-de9e-078343ce4713.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EMENDAPREPITANTMerck Sharp & Dohme LLC696f9e80-9cae-403b-de9e-078343ce47132024-07-05Warnings, Adverse reactionsExact identifier
application applno (NDA): 207865
application number: NDA207865
ndc (product): 0006-3066

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
754509{1 (aprepitant 125 MG Oral Capsule [Emend]) / 2 (aprepitant 80 MG Oral Capsule [Emend]) } Pack [Emend Tri-Fold Pack]BPCK696f9e80-9cae-403b-de9e-078343ce471342
754508{1 (aprepitant 125 MG Oral Capsule) / 2 (aprepitant 80 MG Oral Capsule) } PackGPCK696f9e80-9cae-403b-de9e-078343ce471342
754508aprepitant 125 MG (1), 80 MG (2) Oral Capsule 3 Count PackPSN696f9e80-9cae-403b-de9e-078343ce471342
403811aprepitant 125 MG Oral CapsulePSN696f9e80-9cae-403b-de9e-078343ce471342
1729308aprepitant 125 MG Powder for Oral SuspensionPSN696f9e80-9cae-403b-de9e-078343ce471342
644088aprepitant 40 MG Oral CapsulePSN696f9e80-9cae-403b-de9e-078343ce471342
403810aprepitant 80 MG Oral CapsulePSN696f9e80-9cae-403b-de9e-078343ce471342
404466Emend 125 MG Oral CapsulePSN696f9e80-9cae-403b-de9e-078343ce471342
1729311Emend 125 MG Powder for Oral SuspensionPSN696f9e80-9cae-403b-de9e-078343ce471342
644278Emend 40 MG Oral CapsulePSN696f9e80-9cae-403b-de9e-078343ce471342
404465Emend 80 MG Oral CapsulePSN696f9e80-9cae-403b-de9e-078343ce471342
754509Emend TriPackPSN696f9e80-9cae-403b-de9e-078343ce471342
404466aprepitant 125 MG Oral Capsule [Emend]SBD696f9e80-9cae-403b-de9e-078343ce471342
1729311aprepitant 125 MG Powder for Oral Suspension [Emend]SBD696f9e80-9cae-403b-de9e-078343ce471342
644278aprepitant 40 MG Oral Capsule [Emend]SBD696f9e80-9cae-403b-de9e-078343ce471342
404465aprepitant 80 MG Oral Capsule [Emend]SBD696f9e80-9cae-403b-de9e-078343ce471342
403811aprepitant 125 MG Oral CapsuleSCD696f9e80-9cae-403b-de9e-078343ce471342
1729308aprepitant 125 MG Powder for Oral SuspensionSCD696f9e80-9cae-403b-de9e-078343ce471342
644088aprepitant 40 MG Oral CapsuleSCD696f9e80-9cae-403b-de9e-078343ce471342
403810aprepitant 80 MG Oral CapsuleSCD696f9e80-9cae-403b-de9e-078343ce471342
404466Emend 125 MG Oral CapsuleSY696f9e80-9cae-403b-de9e-078343ce471342
1729311Emend 125 MG Powder for Oral SuspensionSY696f9e80-9cae-403b-de9e-078343ce471342
644278Emend 40 MG Oral CapsuleSY696f9e80-9cae-403b-de9e-078343ce471342
404465Emend 80 MG Oral CapsuleSY696f9e80-9cae-403b-de9e-078343ce471342
754509Emend Tri-Fold PackSY696f9e80-9cae-403b-de9e-078343ce471342

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0006-3066-01000063066011 in 1 POUCHHistorical
0006-3066-03000063066031 POUCH in 1 CARTON (0006-3066-03) / 1 POWDER, FOR SUSPENSION in 1 POUCH (0006-3066-01) 1 pouch2015-12-170000-00-00NoNoCurrent