Home NDC 0006-3066 EMEND
Product NDC 0006-3066
11-digit product format 000063066
Labeler code 0006
Product ID 0006-3066_428f7828-6d1c-438b-a17d-b4af0700c740
Type HUMAN PRESCRIPTION DRUG
Nonproprietary name aprepitant
Dosage form POWDER, FOR SUSPENSION
Route ORAL
Labeler Merck Sharp & Dohme LLC
Application NDA207865
Marketing category NDA
Marketing start 2015-12-17
Substance APREPITANT
Active strength 125 mg/1
Pharmacologic classes Cytochrome P450 2C9 Inducers [MoA], Cytochrome P450 3A4 Inducers [MoA], Cytochrome P450 3A4 Inhibitors [MoA], Neurokinin 1 Antagonists [MoA], Substance P/Neurokinin-1 Receptor Antagonist [EPC]
NDC exclude flag No
Listing certified through 2026-12-31
Current FDA listing Yes Source provenance: Browse the complete Orange Book source catalog · source snapshot 42 .
Orange Book products# Current product rows page 1 of 1 · 1 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date N207865-001 EMEND APREPITANT 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17
Orange Book patents# Current patent rows page 1 of 1 · 1 matching rows.
Application-product, Patent, Expiration table Application-product Patent Expiration Use code Coverage / status Submission date N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 2 · 42 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-08-18 06:07:40 2026-07 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 8072bd15b7f6…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 74a2ff9319b5…2022-03-09 01:35 UTC 2022-03 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 bb7c543d1eb4…2021-12-28 21:50 UTC 2021-12 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 782e0a99824c…2021-05-05 16:15 UTC · 3 captures of this ZIP 2021-05 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 87673890dc5c…2021-03-12 10:30 UTC 2021-03 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 5aa47cf7b7d7…2020-12-22 03:56 UTC 2020-12 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 8869cabd3fbd…2020-11-12 02:37 UTC 2020-11 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 c0c555d07b60…2019-12-14 00:12 UTC 2019-12 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 3f01610625f2…2019-09-15 20:21 UTC 2019-09 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 b00525d2431f…2019-07-19 19:46 UTC 2019-07 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 ea99ee380514…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 1c564ffb4f44…2023-12-20 04:57 UTC 2023-12 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 ea1830bbd6c7…2023-11-28 05:40 UTC · 2 captures of this ZIP 2023-11 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 a72a2bbeb626…2023-10-25 00:34 UTC · 2 captures of this ZIP 2023-10 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 9b2671bbb829…2023-07-15 15:27 UTC · 2 captures of this ZIP 2023-07 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 a67488948f0b…2023-06-13 01:57 UTC · 3 captures of this ZIP 2023-06 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 3f0d92c62455…2023-05-13 08:27 UTC 2023-05 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 053a50430f4f…2023-01-26 05:58 UTC 2023-01 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 3bdfa0b2c4d7…2022-11-12 20:34 UTC · 5 captures of this ZIP 2022-11 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 3a93d1ddd44b…2022-10-28 04:53 UTC 2022-10 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 f41ea6bd6efb…2022-09-29 23:25 UTC 2022-09 N207865-001 EMEND 125MG/KIT FOR SUSPENSION / ORAL RLD, RS 2015-12-17 e64feba35796…
Observed Orange Book patent history# Patent history page 1 of 2 · 42 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Patent Expiration Use code Coverage / status Submission date Source SHA-256 2026-08-18 06:07:40 2026-07 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 caaa826d4ba7…2026-02-19 14:30 UTC 2026-02 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 8072bd15b7f6…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 74a2ff9319b5…2022-03-09 01:35 UTC 2022-03 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 bb7c543d1eb4…2021-12-28 21:50 UTC 2021-12 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 782e0a99824c…2021-05-05 16:15 UTC · 3 captures of this ZIP 2021-05 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 87673890dc5c…2021-03-12 10:30 UTC 2021-03 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 5aa47cf7b7d7…2020-12-22 03:56 UTC 2020-12 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 8869cabd3fbd…2020-11-12 02:37 UTC 2020-11 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 c0c555d07b60…2019-12-14 00:12 UTC 2019-12 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 3f01610625f2…2019-09-15 20:21 UTC 2019-09 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 b00525d2431f…2019-07-19 19:46 UTC 2019-07 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 ea99ee380514…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 1c564ffb4f44…2023-12-20 04:57 UTC 2023-12 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 ea1830bbd6c7…2023-11-28 05:40 UTC · 2 captures of this ZIP 2023-11 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 a72a2bbeb626…2023-10-25 00:34 UTC · 2 captures of this ZIP 2023-10 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 9b2671bbb829…2023-07-15 15:27 UTC · 2 captures of this ZIP 2023-07 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 a67488948f0b…2023-06-13 01:57 UTC · 3 captures of this ZIP 2023-06 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 3f0d92c62455…2023-05-13 08:27 UTC 2023-05 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 053a50430f4f…2023-01-26 05:58 UTC 2023-01 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 3bdfa0b2c4d7…2022-11-12 20:34 UTC · 5 captures of this ZIP 2022-11 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 3a93d1ddd44b…2022-10-28 04:53 UTC 2022-10 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 f41ea6bd6efb…2022-09-29 23:25 UTC 2022-09 N207865-001 8258132 2027-09-26 U-1916 Drug product 2016-11-18 e64feba35796…
Additional Listing Data#
Finished product Yes
Brand name base EMEND
Listing expiration 2026-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength APREPITANT 125 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 1NF15YR6UY Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 10 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 403810 Internal RxNorm lookup 403811 Internal RxNorm lookup 404465 Internal RxNorm lookup 404466 Internal RxNorm lookup 644088 Internal RxNorm lookup 644278 Internal RxNorm lookup 754508 Internal RxNorm lookup 754509 Internal RxNorm lookup 1729308 Internal RxNorm lookup 1729311 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 0006-3066-01 EMEND 1 in 1 POUCH POWDER, FOR SUSPENSION 1 42 0006-3066-03 EMEND 1 in 1 CARTON POWDER, FOR SUSPENSION 1 42
DailyMed Socrata Ingredients# DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 0006-3066 EMEND (APREPITANT) CAPSULE EMEND (APREPITANT) KIT EMEND (APREPITANT) POWDER, FOR SUSPENSION [MERCK SHARP & DOHME LLC] 41 Current NDC, Legacy NDC, 2 package rows 20240719_696f9e80-9cae-403b-de9e-078343ce4713.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Marketing end Sample Exclude flag Status 0006-3066-01 00006306601 1 in 1 POUCH Historical 0006-3066-03 00006306603 1 POUCH in 1 CARTON (0006-3066-03) / 1 POWDER, FOR SUSPENSION in 1 POUCH (0006-3066-01) 1 pouch 2015-12-17 0000-00-00 No No Current