REFRESH LACRI-LUBE

Product NDC: 0023-0312
11-digit product format: 000230312
Labeler code: 0023
Product ID: 0023-0312_b6d64a52-8a8a-4c90-ac67-41a32cc3c78a
Type: HUMAN OTC DRUG
Nonproprietary name: mineral oil, petrolatum
Dosage form: OINTMENT
Route: OPHTHALMIC
Labeler: Allergan, Inc.
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 1977-12-15
Substance: MINERAL OIL; PETROLATUM
Active strength: 425; 568 mg/g; mg/g
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: REFRESH LACRI-LUBE
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
MINERAL OIL	425 mg/g
PETROLATUM	568 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
T5L8T28FGP	Internal UNII lookup
4T6H12BN9U	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
701984	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
d232a44b-516d-4cdf-a4e7-c3a9a50dc7af	Available on FDA.report

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0023-0312-04	REFRESH LACRI-LUBE	1 in 1 CARTON	OINTMENT	1	8
0023-0312-04	REFRESH LACRI-LUBE	3.5 g in 1 TUBE	OINTMENT	3.5	8
0023-0312-07	REFRESH LACRI-LUBE	1 in 1 CARTON	OINTMENT	1	8
0023-0312-07	REFRESH LACRI-LUBE	7 g in 1 TUBE	OINTMENT	7	8

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0023-0312-04	GM - Gram	0023-0312	20b39866-d70e-43a9-aba4-f2788fd84ed8	1	2012-07-24
0023-0312-07	GM - Gram	0023-0312	908fe98b-82bb-4d73-892c-9c93a24b96d6	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
mineral oil	ACTIVE INGREDIENT	T5L8T28FGP	REFRESH LACRI-LUBE (MINERAL OIL, PETROLATUM) OINTMENT [ALLERGAN, INC.]	2
petrolatum	ACTIVE INGREDIENT	4T6H12BN9U	REFRESH LACRI-LUBE (MINERAL OIL, PETROLATUM) OINTMENT [ALLERGAN, INC.]	2
mineral oil	ACTIVE MOIETY	T5L8T28FGP	REFRESH LACRI-LUBE (MINERAL OIL, PETROLATUM) OINTMENT [ALLERGAN, INC.]	2
petrolatum	ACTIVE MOIETY	4T6H12BN9U	REFRESH LACRI-LUBE (MINERAL OIL, PETROLATUM) OINTMENT [ALLERGAN, INC.]	2
chlorobutanol	INACTIVE INGREDIENT	HM4YQM8WRC	REFRESH LACRI-LUBE (MINERAL OIL, PETROLATUM) OINTMENT [ALLERGAN, INC.]	2
lanolin alcohols	INACTIVE INGREDIENT	884C3FA9HE	REFRESH LACRI-LUBE (MINERAL OIL, PETROLATUM) OINTMENT [ALLERGAN, INC.]	2
MINERAL OIL	ACTIVE INGREDIENT	T5L8T28FGP	MINERAL OIL (LACRI-LUBE) OINTMENT [REBEL DISTRIBUTORS CORP]	1
PETROLATUM	ACTIVE INGREDIENT	4T6H12BN9U	MINERAL OIL (LACRI-LUBE) OINTMENT [REBEL DISTRIBUTORS CORP]	1
MINERAL OIL	ACTIVE MOIETY	T5L8T28FGP	MINERAL OIL (LACRI-LUBE) OINTMENT [REBEL DISTRIBUTORS CORP]	1
PETROLATUM	ACTIVE MOIETY	4T6H12BN9U	MINERAL OIL (LACRI-LUBE) OINTMENT [REBEL DISTRIBUTORS CORP]	1
CHLOROBUTANOL	INACTIVE INGREDIENT	HM4YQM8WRC	MINERAL OIL (LACRI-LUBE) OINTMENT [REBEL DISTRIBUTORS CORP]	1
LANOLIN ALCOHOLS	INACTIVE INGREDIENT	884C3FA9HE	MINERAL OIL (LACRI-LUBE) OINTMENT [REBEL DISTRIBUTORS CORP]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0023-0312	REFRESH LACRI-LUBE (MINERAL OIL, PETROLATUM) OINTMENT [ALLERGAN, INC.]	7	Current NDC, Legacy NDC, 4 package rows	20231215_d232a44b-516d-4cdf-a4e7-c3a9a50dc7af.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 5 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Redicare LLC	4d1e5089-22b0-7b3f-e063-6294a90a346a	2026-03-16	Warnings	Exact identifier application number: M018
Leader Ultra Lubricating Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Cardinal Health	d7f011a2-05ba-47c3-9519-d31602e105c7	2026-03-12	Warnings	Exact identifier application number: M018
Leader Restorative Formula Lubricant Eye Drops	PROPYLENE GLYCOL	Cardinal Health	87fef7e4-e5a8-4aad-94d2-f80f34826d97	2026-03-12	Warnings	Exact identifier application number: M018
Leader Advanced Relief Eye Drops	DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL	Cardinal Health	5c5d6c13-9b51-48f0-8627-b60b0f707fd3	2026-03-12	Warnings	Exact identifier application number: M018
Focus PI	HYPROMELLOSE EYE DROPS 0.7%	COVALENT MEDICAL	e9b2afdd-049a-3987-e053-2a95a90a6cbb	2026-03-09	Warnings	Exact identifier application number: M018
Rain Renewal Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Rain Eye Drops, LLC	bb451b22-c4f6-291d-e053-2a95a90a7801	2026-03-06	Warnings	Exact identifier application number: M018
Complete Eye Relief Sterile Lubricant Eye Drops	HYDROXYETHYL CELLULOSE	Similasan Corporation	4c49493a-70f9-0fde-e063-6394a90aea20	2026-03-05	Warnings	Exact identifier application number: M018
Dry Eye Relief Sterile Lubricant Eye Drops	GLYCERIN	Similasan Corporation	4c4cce1c-392e-354d-e063-6294a90a0ca3	2026-03-05	Warnings	Exact identifier application number: M018
Irritated Eye Relief Sterile Lubricant Eye Drops	HYDROXYETHYL CELLULOSE	Similasan Corporation	4c4ddcdf-3037-c9cd-e063-6294a90a16d5	2026-03-05	Warnings	Exact identifier application number: M018
Refresh Optive Mega-3 PF	CARBOXYMETHYLCELLULOSE SODIUM, GLYCERIN, POLYSORBATE 80	Allergan, Inc.	326cb5d6-c784-404f-9a13-6d69262dda6e	2026-03-01	Warnings	Exact identifier application number: M018
Discount Drug Mart Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Discount Drug Mart	4ba1b369-54e2-5224-e063-6394a90a4769	2026-02-25	Warnings	Exact identifier application number: M018
Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	KC Pharmaceuticals, Inc.	4bafa882-50b7-e3e2-e063-6294a90a76e3	2026-02-25	Warnings	Exact identifier application number: M018
Viva Hydration Boost	GLYCERIN	Nomax Inc	174193b2-65eb-b5fd-e063-6394a90a9cd0	2026-02-10	Warnings	Exact identifier application number: M018
Droptics Performance Eye Drops	NAPHAZOLINE HYDROCHLORIDE, PROPYLENE GLYCOL	Droptics LLC	20fd6822-a7fd-4593-92bb-0a07260893e2	2026-02-09	Warnings	Exact identifier application number: M018
GoodSense Eye Drops Advanced Relief Moisturizer	DEXTRAN, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL	Sportpharm LLC	8d58dcbb-72a0-41f0-9eeb-613072a6d7ae	2026-02-06	Warnings	Exact identifier application number: M018
MINIDROPS	LUBRICANT EYE DROPS	Optics Laboratory, Inc	c13c5f91-50df-471c-a7c9-1747a2ac1250	2026-02-03	Warnings	Exact identifier application number: M018
Optase	WHITE PETROLATUM, LANOLIN	Scope Health Inc	c1991caa-51b9-13d1-e053-2995a90a1293	2026-01-31	Warnings	Exact identifier application number: M018
Optase	GLYCERIN	Scope Health Inc	376e0289-28e9-e87f-e063-6294a90a3b04	2026-01-30	Warnings	Exact identifier application number: M018
Optase	GLYCERIN	Scope Health Inc	10c3e31d-779d-8ff6-e063-6294a90acd39	2026-01-30	Warnings	Exact identifier application number: M018
Optase	GLYCERIN	Scope Health Inc	9e96976b-2990-79e0-e053-2995a90a0f29	2026-01-30	Warnings	Exact identifier application number: M018

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
T5L8T28FGP	MINERAL OIL	8042-47-5	MINERAL OIL
4T6H12BN9U	PETROLATUM	8009-03-8	PETROLATUM

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
701984	mineral oil 42.5 % / petrolatum 56.8 % Ophthalmic Ointment	PSN	d232a44b-516d-4cdf-a4e7-c3a9a50dc7af	8
701984	mineral oil 0.425 MG/MG / petrolatum 0.568 MG/MG Ophthalmic Ointment	SCD	d232a44b-516d-4cdf-a4e7-c3a9a50dc7af	8
701984	mineral oil 42.5 % / petrolatum, white 56.8 % Ophthalmic Ointment	SY	d232a44b-516d-4cdf-a4e7-c3a9a50dc7af	8
701984	mineral oil 42.5 % / petrolatum 56.8 % Ophthalmic Ointment	PSN	3f0ec253-6179-4609-8a67-00dbefc55033	1
701984	mineral oil 0.425 MG/MG / petrolatum 0.568 MG/MG Ophthalmic Ointment	SCD	3f0ec253-6179-4609-8a67-00dbefc55033	1
701984	mineral oil 42.5 % / petrolatum, white 56.8 % Ophthalmic Ointment	SY	3f0ec253-6179-4609-8a67-00dbefc55033	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0023-0312-04	00023031204	1 TUBE in 1 CARTON (0023-0312-04) / 3.5 g in 1 TUBE	1 tube	1977-12-15	0000-00-00	No	No	Current
0023-0312-07	00023031207	1 TUBE in 1 CARTON (0023-0312-07) / 7 g in 1 TUBE	1 tube	1977-12-15	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
REFRESH ® LACRI-LUBE ® Drug Facts	Allergan, Inc.	2026-05-15	HUMAN OTC DRUG LABEL	8
Lacri-Lube Drug Facts	Rebel Distributors Corp	2011-02-17	HUMAN OTC DRUG LABEL	1