REFRESH TEARS
- Product NDC
- 0023-0798
- 11-digit product format
- 000230798
- Labeler code
- 0023
- Product ID
- 0023-0798_104a1738-87e4-4eae-b584-93ceb264f77a
- Type
- HUMAN OTC DRUG
- Nonproprietary name
- carboxymethylcellulose sodium
- Dosage form
- SOLUTION/ DROPS
- Route
- OPHTHALMIC
- Labeler
- Allergan, Inc.
- Application
- M018
- Marketing category
- OTC MONOGRAPH DRUG
- Marketing start
- 1997-05-16
- Substance
- CARBOXYMETHYLCELLULOSE SODIUM
- Active strength
- 5 mg/mL
- NDC exclude flag
- No
- Listing certified through
- 2026-12-31
- Current FDA listing
- Yes
NDC auxiliary status#
These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.
| Dataset | Scope | Product NDC | Package NDC | Code | Status | Reporting period | Source date |
|---|---|---|---|---|---|---|---|
| excluded package | package | 0023-0798 | 0023-0798-02 | D | Discontinued by firm | 2026-10-15 |
Observed NDC auxiliary status history#
This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
| Captured / source date | Snapshot | Source SHA-256 |
|---|---|---|
| 2025-12-14 17:58 UTC · source 2025-12-05 | d630ba8d3edf… | 732f749b63fb… |
| 2025-08-27 00:01 UTC · source 2025-08-26 | f5e01cc5f278… | a2eaf40c39c3… |
| 2025-04-01 02:39 UTC · source 2025-03-31 | 2ef7874e63bc… | 57b86245f4fa… |
| 2025-03-28 20:22 UTC · source 2025-03-28 | a1b67e2a42f9… | c4cf2c586c0d… |
| 2025-03-22 03:12 UTC · source 2025-03-21 | cfe11265f3b6… | 090c488252e2… |
| 2025-03-10 12:48 UTC · source 2025-03-10 | cdf11ea48f46… | ba0047e9e063… |
| 2025-02-02 03:52 UTC · source 2025-01-31 | 302b2466d912… | e7b80fea0513… |
| 2025-01-20 13:05 UTC · source 2025-01-20 | ed331223b511… | 672a5bd82f5f… |
| 2025-01-11 03:41 UTC · source 2025-01-10 | 0efc9e666f02… | f202fb6c5f17… |
| 2024-11-09 02:27 UTC · source 2024-11-08 | ad56d346431e… | cc804d4bbf1e… |
| 2024-10-04 04:10 UTC · source 2024-10-03 | 367a005e9d99… | 383a685ebd0f… |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
- Finished product
- Yes
- Brand name base
- REFRESH TEARS
- Listing expiration
- 2026-12-31
Active Ingredients#
| Ingredient | Strength |
|---|---|
| CARBOXYMETHYLCELLULOSE SODIUM | 5 mg/mL |
Harmonized UNII identifiers#
| Identifier | FDA.report destination |
|---|---|
| K679OBS311 | Internal UNII lookup |
Harmonized RxCUI identifiers#
| Identifier | FDA.report destination |
|---|---|
| 1188426 | Internal RxNorm lookup |
Harmonized SPL set identifiers#
| Identifier | FDA.report destination |
|---|---|
| 329d1fe0-4432-4565-b7b1-65666bd86526 | Available on FDA.report |
DailyMed Product Concepts#
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 0023-0798-01 | REFRESH TEARS | 2 in 1 CARTON | SOLUTION/ DROPS | 2 | 9 | |
| 0023-0798-01 | REFRESH TEARS | 15 mL in 1 BOTTLE, DROPPER | SOLUTION/ DROPS | 15 | 9 | |
| 0023-0798-02 | REFRESH TEARS | 15 mL in 1 BOTTLE, DROPPER | SOLUTION/ DROPS | 15 | 9 | |
| 0023-0798-02 | REFRESH TEARS | 4 in 1 CARTON | SOLUTION/ DROPS | 4 | 9 | |
| 0023-0798-03 | REFRESH TEARS | 1 in 1 CARTON | SOLUTION/ DROPS | 1 | 9 | |
| 0023-0798-03 | REFRESH TEARS | 3 mL in 1 BOTTLE, DROPPER | SOLUTION/ DROPS | 3 | 9 | |
| 0023-0798-04 | REFRESH TEARS | 1 in 1 CARTON | SOLUTION/ DROPS | 1 | 9 | |
| 0023-0798-04 | REFRESH TEARS | 3 mL in 1 BOTTLE, DROPPER | SOLUTION/ DROPS | 3 | 9 | |
| 0023-0798-15 | REFRESH TEARS | 15 mL in 1 BOTTLE, DROPPER | SOLUTION/ DROPS | 15 | 9 | |
| 0023-0798-15 | REFRESH TEARS | 1 in 1 CARTON | SOLUTION/ DROPS | 1 | 9 |
DailyMed Billing Units#
| Package NDC | Billing unit | Product NDC | DailyMed indexing SPL | SPL version | Effective |
|---|---|---|---|---|---|
| 0023-0798-01 | ML - Milliliter | 0023-0798 | 62c6f21f-4516-4eea-ba68-d29b027aea04 | 1 | 2012-07-24 |
| 0023-0798-02 | ML - Milliliter | 0023-0798 | 22f1d5bd-fff4-45c7-a80b-b75da37562a1 | 1 | 2012-07-24 |
| 0023-0798-15 | ML - Milliliter | 0023-0798 | a409ce19-82da-4f27-91e4-8c86819535dc | 1 | 2012-07-24 |
DailyMed Socrata Ingredients#
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 0023-0798 | REFRESH TEARS (CARBOXYMETHYLCELLULOSE SODIUM) SOLUTION/ DROPS REFRESH TEARS (CARBOXYMETHYLCELLULOSE SODIUM) KIT [ALLERGAN, INC.] | 9 | Current NDC, Legacy NDC, 10 package rows | 20240927_329d1fe0-4432-4565-b7b1-65666bd86526.zip |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Lubricant Eye Drops | CARBOXYMETHYLCELLULOSE SODIUM | Redicare LLC | 4d1e5089-22b0-7b3f-e063-6294a90a346a | 2026-03-16 | Warnings | M018 |
| Leader Ultra Lubricating Eye Drops | POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL | Cardinal Health | d7f011a2-05ba-47c3-9519-d31602e105c7 | 2026-03-12 | Warnings | M018 |
| Leader Restorative Formula Lubricant Eye Drops | PROPYLENE GLYCOL | Cardinal Health | 87fef7e4-e5a8-4aad-94d2-f80f34826d97 | 2026-03-12 | Warnings | M018 |
| Leader Advanced Relief Eye Drops | DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL | Cardinal Health | 5c5d6c13-9b51-48f0-8627-b60b0f707fd3 | 2026-03-12 | Warnings | M018 |
| Focus PI | HYPROMELLOSE EYE DROPS 0.7% | COVALENT MEDICAL | e9b2afdd-049a-3987-e053-2a95a90a6cbb | 2026-03-09 | Warnings | M018 |
| Rain Renewal Eye Drops | CARBOXYMETHYLCELLULOSE SODIUM | Rain Eye Drops, LLC | bb451b22-c4f6-291d-e053-2a95a90a7801 | 2026-03-06 | Warnings | M018 |
| Complete Eye Relief Sterile Lubricant Eye Drops | HYDROXYETHYL CELLULOSE | Similasan Corporation | 4c49493a-70f9-0fde-e063-6394a90aea20 | 2026-03-05 | Warnings | M018 |
| Dry Eye Relief Sterile Lubricant Eye Drops | GLYCERIN | Similasan Corporation | 4c4cce1c-392e-354d-e063-6294a90a0ca3 | 2026-03-05 | Warnings | M018 |
| Irritated Eye Relief Sterile Lubricant Eye Drops | HYDROXYETHYL CELLULOSE | Similasan Corporation | 4c4ddcdf-3037-c9cd-e063-6294a90a16d5 | 2026-03-05 | Warnings | M018 |
| Refresh Optive Mega-3 PF | CARBOXYMETHYLCELLULOSE SODIUM, GLYCERIN, POLYSORBATE 80 | Allergan, Inc. | 326cb5d6-c784-404f-9a13-6d69262dda6e | 2026-03-01 | Warnings | M018 |
| Discount Drug Mart Lubricant Eye Drops | CARBOXYMETHYLCELLULOSE SODIUM | Discount Drug Mart | 4ba1b369-54e2-5224-e063-6394a90a4769 | 2026-02-25 | Warnings | M018 |
| Lubricant Eye Drops | CARBOXYMETHYLCELLULOSE SODIUM | KC Pharmaceuticals, Inc. | 4bafa882-50b7-e3e2-e063-6294a90a76e3 | 2026-02-25 | Warnings | M018 |
| Viva Hydration Boost | GLYCERIN | Nomax Inc | 174193b2-65eb-b5fd-e063-6394a90a9cd0 | 2026-02-10 | Warnings | M018 |
| Droptics Performance Eye Drops | NAPHAZOLINE HYDROCHLORIDE, PROPYLENE GLYCOL | Droptics LLC | 20fd6822-a7fd-4593-92bb-0a07260893e2 | 2026-02-09 | Warnings | M018 |
| GoodSense Eye Drops Advanced Relief Moisturizer | DEXTRAN, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL | Sportpharm LLC | 8d58dcbb-72a0-41f0-9eeb-613072a6d7ae | 2026-02-06 | Warnings | M018 |
| MINIDROPS | LUBRICANT EYE DROPS | Optics Laboratory, Inc | c13c5f91-50df-471c-a7c9-1747a2ac1250 | 2026-02-03 | Warnings | M018 |
| Optase | WHITE PETROLATUM, LANOLIN | Scope Health Inc | c1991caa-51b9-13d1-e053-2995a90a1293 | 2026-01-31 | Warnings | M018 |
| Optase | GLYCERIN | Scope Health Inc | 376e0289-28e9-e87f-e063-6294a90a3b04 | 2026-01-30 | Warnings | M018 |
| Optase | GLYCERIN | Scope Health Inc | 10c3e31d-779d-8ff6-e063-6294a90acd39 | 2026-01-30 | Warnings | M018 |
| Optase | GLYCERIN | Scope Health Inc | 9e96976b-2990-79e0-e053-2995a90a0f29 | 2026-01-30 | Warnings | M018 |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | DailyMed | SPL version |
|---|---|---|---|---|
| 1188426 | carboxymethylcellulose sodium 0.5 % Ophthalmic Solution | PSN | 3b94f67c-d675-4e16-846a-3ca39b0405e0 | 14 |
| 1188426 | carboxymethylcellulose sodium 5 MG/ML Ophthalmic Solution | SCD | 3b94f67c-d675-4e16-846a-3ca39b0405e0 | 14 |
| 1188426 | carboxymethylcellulose sodium 0.5 % Ophthalmic Solution | SY | 3b94f67c-d675-4e16-846a-3ca39b0405e0 | 14 |
| 1188426 | carboxymethylcellulose sodium 0.5 GM per 100 ML Ophthalmic Solution | SY | 3b94f67c-d675-4e16-846a-3ca39b0405e0 | 14 |
| 1188426 | carboxymethylcellulose sodium 0.5 % Ophthalmic Solution | PSN | 329d1fe0-4432-4565-b7b1-65666bd86526 | 9 |
| 1188426 | carboxymethylcellulose sodium 5 MG/ML Ophthalmic Solution | SCD | 329d1fe0-4432-4565-b7b1-65666bd86526 | 9 |
| 1188426 | carboxymethylcellulose sodium 0.5 % Ophthalmic Solution | SY | 329d1fe0-4432-4565-b7b1-65666bd86526 | 9 |
| 1188426 | carboxymethylcellulose sodium 0.5 GM per 100 ML Ophthalmic Solution | SY | 329d1fe0-4432-4565-b7b1-65666bd86526 | 9 |
| 1188426 | carboxymethylcellulose sodium 0.5 % Ophthalmic Solution | PSN | cd467181-9d56-4b11-9826-15b5357d0689 | 2 |
| 1188426 | carboxymethylcellulose sodium 5 MG/ML Ophthalmic Solution | SCD | cd467181-9d56-4b11-9826-15b5357d0689 | 2 |
| 1188426 | carboxymethylcellulose sodium 0.5 % Ophthalmic Solution | SY | cd467181-9d56-4b11-9826-15b5357d0689 | 2 |
| 1188426 | carboxymethylcellulose sodium 0.5 GM per 100 ML Ophthalmic Solution | SY | cd467181-9d56-4b11-9826-15b5357d0689 | 2 |
Packages#
| Package NDC | 11-digit format | Description | Marketing start | Marketing end | Sample | Exclude flag | Status |
|---|---|---|---|---|---|---|---|
| 0023-0798-01 | 00023079801 | 2 BOTTLE, DROPPER in 1 CARTON (0023-0798-01) / 15 mL in 1 BOTTLE, DROPPER | 1997-05-16 | 0000-00-00 | No | No | Current |
| 0023-0798-02 | 00023079802 | 4 BOTTLE, DROPPER in 1 CARTON (0023-0798-02) > 15 mL in 1 BOTTLE, DROPPER | 1997-05-16 | 0000-00-00 | No | No | Current |
| 0023-0798-03 | 00023079803 | 1 BOTTLE, DROPPER in 1 CARTON (0023-0798-03) / 3 mL in 1 BOTTLE, DROPPER | 1997-05-16 | 0000-00-00 | Yes | No | Current |
| 0023-0798-04 | 00023079804 | 1 BOTTLE, DROPPER in 1 CARTON (0023-0798-04) / 3 mL in 1 BOTTLE, DROPPER | 1997-05-16 | 0000-00-00 | Yes | No | Current |
| 0023-0798-15 | 00023079815 | 1 BOTTLE, DROPPER in 1 CARTON (0023-0798-15) / 15 mL in 1 BOTTLE, DROPPER | 1997-05-16 | 0000-00-00 | No | No | Current |