Fexinidazole

Product NDC
0024-4512
11-digit product format
000244512
Labeler code
0024
Product ID
0024-4512_1b3dbe65-328a-450b-bc3d-0b46d9acd832
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Fexinidazole
Dosage form
TABLET
Route
ORAL
Labeler
Sanofi-Aventis U.S. LLC
Application
NDA214429
Marketing category
NDA
Marketing start
2021-07-16
Substance
FEXINIDAZOLE
Active strength
600 mg/1
Pharmacologic classes
Cytochrome P450 1A2 Inducers [MoA], Cytochrome P450 1A2 Inhibitors [MoA], Cytochrome P450 2B6 Inducers [MoA], Cytochrome P450 2B6 Inhibitors [MoA], Cytochrome P450 2C19 Inhibitors [MoA], Cytochrome P450 2D6 Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], Cytochrome P450 3A5 Inhibitors [MoA], Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA], Multidrug and Toxin Extrusion Transporter 2 K Inhibitors [MoA], Nitroimidazole Antimicrobial [EPC], Nitroimidazoles [CS], Organic Anion Transporter 1 Inhibitors [MoA], Organic Anion Transporter 3 Inhibitors [MoA], Organic Anion Transporting Polypeptide 1B1 Inhibitors [MoA], Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA], Organic Cation Transporter 2 Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N214429-001FEXINIDAZOLEFEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 2 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N214429-001NCE2026-07-16
N214429-001ODE-3592028-07-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-1679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-161e350fbaab3a…
2024-05-31 18:47 UTC2024-05N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-168072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-165c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-165d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-164b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-166a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-161c564ffb4f44…
2023-12-20 04:57 UTC2023-12N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-169b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-163f0d92c62455…
2023-05-13 08:27 UTC2023-05N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16053a50430f4f…
2023-01-26 05:58 UTC2023-01N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-163bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-163a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N214429-001FEXINIDAZOLE600MGTABLET / ORALRLD, RS2021-07-16a50c72e98297…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 66 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N214429-001NCE2026-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N214429-001ODE-3592028-07-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214429-001NCE2026-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N214429-001ODE-3592028-07-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N214429-001NCE2026-07-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N214429-001ODE-3592028-07-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214429-001NCE2026-07-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N214429-001ODE-3592028-07-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214429-001NCE2026-07-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N214429-001ODE-3592028-07-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214429-001NCE2026-07-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N214429-001ODE-3592028-07-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214429-001NCE2026-07-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N214429-001ODE-3592028-07-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214429-001NCE2026-07-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N214429-001ODE-3592028-07-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214429-001NCE2026-07-16d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N214429-001ODE-3592028-07-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N214429-001NCE2026-07-16d06236e962d9…
2024-10-29 15:01 UTC2024-10N214429-001ODE-3592028-07-16d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214429-001NCE2026-07-1679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N214429-001ODE-3592028-07-1679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214429-001NCE2026-07-16301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N214429-001ODE-3592028-07-16301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214429-001NCE2026-07-161e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N214429-001ODE-3592028-07-161e350fbaab3a…
2024-05-31 18:47 UTC2024-05N214429-001NCE2026-07-168072bd15b7f6…
2024-05-31 18:47 UTC2024-05N214429-001ODE-3592028-07-168072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N214429-001NCE2026-07-165c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N214429-001ODE-3592028-07-165c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N214429-001NCE2026-07-165d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N214429-001ODE-3592028-07-165d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N214429-001NCE2026-07-164b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N214429-001ODE-3592028-07-164b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N214429-001NCE2026-07-16bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N214429-001ODE-3592028-07-16bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N214429-001NCE2026-07-16782e0a99824c…
2021-12-28 21:50 UTC2021-12N214429-001ODE-3592028-07-16782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214429-001NCE2026-07-166a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N214429-001ODE-3592028-07-166a51e52b5d6a…

Additional Listing Data#

Finished product
Yes
Brand name base
Fexinidazole
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
FEXINIDAZOLE600 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
306ERL82IRInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2564151Internal RxNorm lookup
2564152Internal RxNorm lookup
2564153Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
74a611bc-9977-46bb-b626-0370b3031628Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
93ff0951-ed65-4166-8945-7e655edb8103Product name120220126

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0024-4512-14Fexinidazole14 in 1 DOSE PACKTABLET1410
0024-4512-24Fexinidazole24 in 1 DOSE PACKTABLET2410

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0024-4512-14EA - Each0024-45120ed082cb-d9eb-4e2a-b19f-9d481542243112024-01-04
0024-4512-24EA - Each0024-4512222b5725-ee80-422b-9dce-b4b1c6d08e2d12024-12-10

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0024-4512FEXINIDAZOLE TABLET [SANOFI-AVENTIS U.S. LLC]10Current NDC, Legacy NDC, 2 package rows20250507_74a611bc-9977-46bb-b626-0370b3031628.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
FexinidazoleFEXINIDAZOLESanofi-Aventis U.S. LLC74a611bc-9977-46bb-b626-0370b30316282025-05-02Warnings, Adverse reactionsExact identifier
application applno (NDA): 214429
application number: NDA214429
ndc (product): 0024-4512

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2564153{14 (fexinidazole 600 MG Oral Tablet) } PackGPCK74a611bc-9977-46bb-b626-0370b303162810
2564152{24 (fexinidazole 600 MG Oral Tablet) } PackGPCK74a611bc-9977-46bb-b626-0370b303162810
2564151fexinidazole 600 MG Oral TabletPSN74a611bc-9977-46bb-b626-0370b303162810
2564153fexinidazole 600 MG Tablet 10-Day Dose Pack (20 KG - < 35 KG)PSN74a611bc-9977-46bb-b626-0370b303162810
2564152fexinidazole 600 MG Tablet 10-Day Dose Pack (35 KG+)PSN74a611bc-9977-46bb-b626-0370b303162810
2564151fexinidazole 600 MG Oral TabletSCD74a611bc-9977-46bb-b626-0370b303162810
2564153fexinidazole 600 MG Tablet 10-Day Dose Pack (20 KG - < 35 KG)SY74a611bc-9977-46bb-b626-0370b303162810
2564152fexinidazole 600 MG Tablet 10-Day Dose Pack (35 KG+)SY74a611bc-9977-46bb-b626-0370b303162810

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0024-4512-140002445121414 TABLET in 1 DOSE PACK (0024-4512-14) 14 tablet2021-07-160000-00-00NoNoCurrent
0024-4512-240002445122424 TABLET in 1 DOSE PACK (0024-4512-24) 24 tablet2021-07-160000-00-00NoNoCurrent