Digoxin

Product NDC
0054-0057
11-digit product format
000540057
Labeler code
0054
Product ID
0054-0057_db501397-8e41-4498-8626-49c6bfd79971
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Digoxin
Dosage form
SOLUTION
Route
ORAL
Labeler
Hikma Pharmaceuticals USA Inc.
Application
NDA021648
Marketing category
NDA
Marketing start
2004-08-26
Substance
DIGOXIN
Active strength
.05 mg/mL
Pharmacologic classes
Cardiac Glycoside [EPC], Cardiac Glycosides [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021648-001DIGOXINDIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N021648-001AA

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-2631067a03dcf5…
2025-08-23 18:47 UTC2025-08N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-266a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-2603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-262680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-265bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-2679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-261e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-268072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-265c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-265d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-264b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-2674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-2687673890dc5c…
2021-03-12 10:30 UTC2021-03N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-265aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-268869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-263f01610625f2…
2019-09-15 20:21 UTC2019-09N021648-001DIGOXIN0.05MG/MLELIXIR / ORALRLD, RS2004-08-26b00525d2431f…
2019-07-19 19:46 UTC2019-07N021648-001DIGOXIN0.05MG/MLELIXIR / ORALRLD, RS2004-08-26ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-266a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-261c564ffb4f44…
2023-12-20 04:57 UTC2023-12N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-269b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-263f0d92c62455…
2023-05-13 08:27 UTC2023-05N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26053a50430f4f…
2023-01-26 05:58 UTC2023-01N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-263bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-263a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N021648-001DIGOXIN0.05MG/MLELIXIR / ORALAARLD, RS2004-08-26cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021648-001AA1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021648-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021648-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021648-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021648-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021648-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021648-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021648-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021648-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021648-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021648-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021648-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021648-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021648-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021648-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021648-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021648-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021648-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021648-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021648-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021648-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03N021648-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021648-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021648-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021648-001AA13f01610625f2…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N021648-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N021648-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N021648-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N021648-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N021648-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N021648-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N021648-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05N021648-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01N021648-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N021648-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N021648-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N021648-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N021648-001AA1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N021648-001AA1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Digoxin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DIGOXIN.05 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
73K4184T59Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
393245Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1b7e5c6e-e052-41b0-a4ce-05dfe62faaafAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
20d84de3-cb46-44c4-9211-63e833fa2688Product name220221214
4d74103a-bb9b-9034-fbc8-dac635e6e729Product name320221117
5c3aa978-6f46-c7ca-2a83-b57385976beeProduct name120140508
6084a4f4-5437-c9a5-caec-5361ee075a59Product name120140508
90c5639a-61b0-88d6-ddcf-21888e94869aProduct name120140508
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0054-0057-46Digoxin60 mL in 1 BOTTLESOLUTION6018

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0054-0057-46ML - Milliliter0054-00571ec354c5-04ce-4f28-9dc3-5dedc67a0b3112012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
DIGOXINACTIVE INGREDIENT73K4184T59DIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
DIGOXINACTIVE MOIETY73K4184T59DIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
ALCOHOLINACTIVE INGREDIENT3K9958V90MDIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
GLYCERININACTIVE INGREDIENTPDC6A3C0OXDIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
LIME (CITRUS)INACTIVE INGREDIENT8CZS546954DIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TDIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
PROPYLPARABENINACTIVE INGREDIENTZ8IX2SC1OHDIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
SODIUM CITRATEINACTIVE INGREDIENT1Q73Q2JULRDIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
SORBITOLINACTIVE INGREDIENT506T60A25RDIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
WATERINACTIVE INGREDIENT059QF0KO0RDIGOXIN SOLUTION [ROXANE LABORATORIES, INC]10
DIGOXINACTIVE INGREDIENT73K4184T59DIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
DIGOXINACTIVE MOIETY73K4184T59DIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
ALCOHOLINACTIVE INGREDIENT3K9958V90MDIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
GLYCERININACTIVE INGREDIENTPDC6A3C0OXDIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
LIME (CITRUS)INACTIVE INGREDIENT8CZS546954DIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TDIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
PROPYLPARABENINACTIVE INGREDIENTZ8IX2SC1OHDIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
SODIUM CITRATEINACTIVE INGREDIENT1Q73Q2JULRDIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
SORBITOLINACTIVE INGREDIENT506T60A25RDIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6
WATERINACTIVE INGREDIENT059QF0KO0RDIGOXIN SOLUTION [ATLANTIC BIOLOGICALS CORPS]6

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0054-0057DIGOXIN SOLUTION [HIKMA PHARMACEUTICALS USA INC.]18Current NDC, Legacy NDC, 1 package rows20250418_1b7e5c6e-e052-41b0-a4ce-05dfe62faaaf.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DigoxinDIGOXINAtlantic Biologicals Corpsdcf907d9-0f0e-4ecc-a555-7e6dcc08c1662025-12-11Warnings, Adverse reactionsExact identifier
application applno (NDA): 021648
application number: NDA021648
DigoxinDIGOXINHikma Pharmaceuticals USA Inc.1b7e5c6e-e052-41b0-a4ce-05dfe62faaaf2025-04-10Warnings, Adverse reactionsExact identifier
application applno (NDA): 021648
application number: NDA021648
ndc (product): 0054-0057

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
393245digoxin 0.05 MG in 1 mL Oral SolutionPSN1b7e5c6e-e052-41b0-a4ce-05dfe62faaaf18
393245digoxin 0.05 MG/ML Oral SolutionSCD1b7e5c6e-e052-41b0-a4ce-05dfe62faaaf18
393245digoxin 50 MCG per 1 ML Oral SOlutionSY1b7e5c6e-e052-41b0-a4ce-05dfe62faaaf18
393245digoxin 50 MCG/ML Oral SolutionSY1b7e5c6e-e052-41b0-a4ce-05dfe62faaaf18
393245digoxin 0.05 MG in 1 mL Oral SolutionPSNdcf907d9-0f0e-4ecc-a555-7e6dcc08c1668
393245digoxin 0.05 MG/ML Oral SolutionSCDdcf907d9-0f0e-4ecc-a555-7e6dcc08c1668
393245digoxin 50 MCG per 1 ML Oral SOlutionSYdcf907d9-0f0e-4ecc-a555-7e6dcc08c1668
393245digoxin 50 MCG/ML Oral SolutionSYdcf907d9-0f0e-4ecc-a555-7e6dcc08c1668

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0054-0057-460005400574660 mL in 1 BOTTLE (0054-0057-46) 60 ml2004-08-260000-00-00NoNoCurrent