Travatan Z

Product NDC: 0065-0260
11-digit product format: 000650260
Labeler code: 0065
Product ID: 0065-0260_5a91413a-0834-4565-843f-d1f2f4d6460b
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: travoprost
Dosage form: SOLUTION/ DROPS
Route: OPHTHALMIC
Labeler: Alcon Laboratories, Inc
Application: NDA021994
Marketing category: NDA
Marketing start: 2006-10-20
Marketing end: 0000-00-00
Substance: TRAVOPROST
Active strength: 0 mg/mL
Pharmacologic classes: Prostaglandin Analog [EPC],Prostaglandins [CS]
NDC exclude flag: No
Listing certified through: 2021-12-31
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 4 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	0065-0260		D	Discontinued by firm	2026-08-11
excluded package	package	0065-0260	0065-0260-02	D	Discontinued by firm	2026-08-11
excluded package	package	0065-0260	0065-0260-05	D	Discontinued by firm	2026-08-11
excluded package	package	0065-0260	0065-0260-25	D	Discontinued by firm	2026-08-11

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 48 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0065-0260-02	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0065-0260-25	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0065-0260-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0065-0260-02	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0065-0260-25	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0065-0260-05	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0065-0260-02	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0065-0260-25	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0065-0260-05	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0065-0260-02	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0065-0260-25	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0065-0260-05	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0065-0260-02	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0065-0260-25	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0065-0260-05	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0065-0260-02	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0065-0260-25	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0065-0260-05	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0065-0260-02	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0065-0260-25	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0065-0260-05	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0065-0260-02	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0065-0260-25	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0065-0260-05	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0065-0260-02	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0065-0260-25	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0065-0260-05	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0065-0260-02	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0065-0260-25	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0065-0260-05	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0065-0260-02	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0065-0260-25	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0065-0260-05	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0065-0260-02	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0065-0260-25	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0065-0260-05	`557ba5c1ecfa…`	`9c80585c8c6e…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N021994-001	TRAVATAN Z	TRAVOPROST	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT2	RLD, RS	2006-09-21

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-product	TE code
N021994-001	AT2

Orange Book patents#

Current patent rows page 1 of 1 · 3 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Coverage / status	Submission date
N021994-001	8323630	2027-09-20	Drug product	2012-12-18
N021994-001	8388941	2027-09-20	Drug product	2013-03-08
N021994-001	8268299	2029-10-13	Drug product	2012-09-24

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT2	RLD, RS	2006-09-21	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT2	RLD, RS	2006-09-21	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT2	RLD, RS	2006-09-21	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT2	RLD, RS	2006-09-21	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N021994-001	TRAVATAN Z	0.004%	SOLUTION/DROPS / OPHTHALMIC	AT	RLD, RS	2006-09-21	`cb3db0bc1861…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N021994-001	AT2	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021994-001	AT2	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021994-001	AT2	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021994-001	AT2	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021994-001	AT	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021994-001	AT	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021994-001	AT	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021994-001	AT	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021994-001	AT	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N021994-001	AT	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021994-001	AT	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021994-001	AT	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021994-001	AT	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N021994-001	AT	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N021994-001	AT	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N021994-001	AT	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N021994-001	AT	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N021994-001	AT	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N021994-001	AT	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N021994-001	AT	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N021994-001	AT	1	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N021994-001	AT	1	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N021994-001	AT	1	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N021994-001	AT	1	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N021994-001	AT	1	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N021994-001	AT	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N021994-001	AT	1	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N021994-001	AT	1	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N021994-001	AT	1	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N021994-001	AT	1	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N021994-001	AT	1	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N021994-001	AT	1	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N021994-001	AT	1	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N021994-001	AT	1	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N021994-001	AT	1	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N021994-001	AT	1	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N021994-001	AT	1	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N021994-001	AT	1	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N021994-001	AT	1	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N021994-001	AT	1	`cb3db0bc1861…`

Observed Orange Book patent history#

Patent history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Coverage / status	Submission date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021994-001	8388941	2027-09-20	Drug product	2013-03-08	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N021994-001	8268299	2029-10-13	Drug product	2012-09-24	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N021994-001	8323630	2027-09-20	Drug product	2012-12-18	`8072bd15b7f6…`

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
030ce964-9b2d-45aa-b5d3-f78ce03ef61c	Product name	2	20250515
c9a16692-b67d-fe7d-e549-d5c422428aa8	Product name	5	20250305
d244df75-ee9e-4580-9b0c-1e61287c8253	Product name	1	20250102
52ddd23e-485b-499f-9fa1-f86549f4d9c0	Product name	2	20200605

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0065-0260-05	ML - Milliliter	0065-0260	ef25c188-969b-4fb6-a17e-2e93ede6a440	1	2012-07-24
0065-0260-25	ML - Milliliter	0065-0260	2e9764b5-ea54-4c92-b1ab-f1d3facc5bc6	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
TRAVOPROST	ACTIVE INGREDIENT	WJ68R08KX9	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
TRAVOPROST	ACTIVE MOIETY	WJ68R08KX9	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
BORIC ACID	INACTIVE INGREDIENT	R57ZHV85D4	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
HYDROCHLORIC ACID	INACTIVE INGREDIENT	QTT17582CB	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
POLYOXYL 40 CASTOR OIL	INACTIVE INGREDIENT	4ERD2076EF	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
SODIUM HYDROXIDE	INACTIVE INGREDIENT	55X04QC32I	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
SORBITOL	INACTIVE INGREDIENT	506T60A25R	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
WATER	INACTIVE INGREDIENT	059QF0KO0R	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
ZINC CHLORIDE	INACTIVE INGREDIENT	86Q357L16B	TRAVATAN Z (TRAVOPROST) SOLUTION/ DROPS [ALCON LABORATORIES, INC]	11
TRAVOPROST	ACTIVE INGREDIENT	WJ68R08KX9	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
TRAVOPROST	ACTIVE MOIETY	WJ68R08KX9	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
BORIC ACID	INACTIVE INGREDIENT	R57ZHV85D4	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
HYDROCHLORIC ACID	INACTIVE INGREDIENT	QTT17582CB	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
POLYOXYL 40 CASTOR OIL	INACTIVE INGREDIENT	4ERD2076EF	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
SODIUM HYDROXIDE	INACTIVE INGREDIENT	55X04QC32I	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
SORBITOL	INACTIVE INGREDIENT	506T60A25R	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1
ZINC CHLORIDE	INACTIVE INGREDIENT	86Q357L16B	TRAVATAN Z (TRAVOPROST) SOLUTION [PHYSICIANS TOTAL CARE, INC.]	1

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Travatan Z	TRAVOPROST	Sandoz Inc	4b5cffb0-74e0-44e4-8e18-f5d56e9db450	2025-01-31	Warnings, Adverse reactions	Exact identifier application applno (NDA): 021994 application number: NDA021994
Travatan Z	TRAVOPROST	Novartis Pharmaceuticals Corporation	028455e0-ae77-4213-8819-3b58ef7d6a14	2023-06-27	Warnings, Adverse reactions	Exact identifier application applno (NDA): 021994 application number: NDA021994

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
WJ68R08KX9	TRAVOPROST	157283-68-6	TRAVOPROST

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
285032	TRAVATAN Z 0.004 % Ophthalmic Solution	PSN	db08d5f3-6713-4372-a66c-fad3018ef5c6	1
284008	travoprost 0.004 % Ophthalmic Solution	PSN	db08d5f3-6713-4372-a66c-fad3018ef5c6	1
285032	travoprost 0.04 MG/ML Ophthalmic Solution [Travatan]	SBD	db08d5f3-6713-4372-a66c-fad3018ef5c6	1
284008	travoprost 0.04 MG/ML Ophthalmic Solution	SCD	db08d5f3-6713-4372-a66c-fad3018ef5c6	1
285032	Travatan 0.004 % Ophthalmic Solution	SY	db08d5f3-6713-4372-a66c-fad3018ef5c6	1
285032	Travatan 0.04 MG/ML Ophthalmic Solution	SY	db08d5f3-6713-4372-a66c-fad3018ef5c6	1
285032	Travatan Z 0.004 % Ophthalmic Solution	SY	db08d5f3-6713-4372-a66c-fad3018ef5c6	1
284008	travoprost 0.004 % Ophthalmic Solution	SY	db08d5f3-6713-4372-a66c-fad3018ef5c6	1
284008	travoprost 40 MCG/ML Ophthalmic Solution	SY	db08d5f3-6713-4372-a66c-fad3018ef5c6	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0065-0260-02	00065026002	1 BOTTLE in 1 CARTON (0065-0260-02) > 2.5 mL in 1 BOTTLE	1 bottle	2006-10-20	0000-00-00	No	No	Current
0065-0260-05	00065026005	1 BOTTLE in 1 CARTON (0065-0260-05) > 5 mL in 1 BOTTLE	1 bottle	2006-10-20	0000-00-00	No	No	Current
0065-0260-25	00065026025	1 BOTTLE in 1 CARTON (0065-0260-25) > 2.5 mL in 1 BOTTLE	1 bottle	2006-10-20	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Travatan Z	Alcon Laboratories, Inc	2020-04-02	HUMAN PRESCRIPTION DRUG LABEL	17
Travatan Z	Physicians Total Care, Inc.	2011-07-20	HUMAN PRESCRIPTION DRUG LABEL	1