FABHALTA

Product NDC
0078-1189
11-digit product format
000781189
Labeler code
0078
Product ID
0078-1189_f0bead0e-4eed-4db9-a076-1d974eba6b4a
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
iptacopan
Dosage form
CAPSULE
Route
ORAL
Labeler
Novartis Pharmaceuticals Corporation
Application
NDA218276
Marketing category
NDA
Marketing start
2023-12-05
Substance
IPTACOPAN HYDROCHLORIDE
Active strength
200 mg/1
Pharmacologic classes
Complement Factor B Inhibitor [EPC], Complement Factor B Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N218276-001FABHALTAIPTACOPAN HYDROCHLORIDEEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-05

Orange Book patents#

Current patent rows page 1 of 1 · 10 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N218276-001100936632034-07-14U-39802024-09-04
N218276-001100936632034-07-14U-41612024-09-04
N218276-00196829682034-07-14Drug substance, Drug product2023-12-18
N218276-001117239012038-08-30U-39802024-09-04
N218276-001122854222038-08-30U-41812025-05-19
N218276-001123847582041-05-17U-39802025-08-20
N218276-001123847582041-05-17U-41612025-08-20
N218276-001116033632041-05-25Drug substance, Drug product2023-12-18
N218276-001119511012041-07-15U-38952024-05-07
N218276-001124537262041-07-15U-43002025-11-04

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 5 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N218276-001I-9492027-08-07
N218276-001I-9632028-03-20
N218276-001NCE2028-12-05
N218276-001ODE-4562030-12-05
N218276-001ODE-5242032-03-20

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-058072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-051c564ffb4f44…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N218276-001FABHALTAEQ 200MG BASECAPSULE / ORALRLD, RS2023-12-05a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 3 · 88 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N218276-001100936632034-07-14U-41612024-09-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001100936632034-07-14U-39802024-09-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-00196829682034-07-14Drug substance, Drug product2023-12-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001117239012038-08-30U-39802024-09-04011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001122854222038-08-30U-41812025-05-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001123847582041-05-17U-39802025-08-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001123847582041-05-17U-41612025-08-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001116033632041-05-25Drug substance, Drug product2023-12-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001119511012041-07-15U-38952024-05-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001124537262041-07-15U-43002025-11-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001100936632034-07-14U-41612024-09-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001100936632034-07-14U-39802024-09-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-00196829682034-07-14Drug substance, Drug product2023-12-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001117239012038-08-30U-39802024-09-0431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001122854222038-08-30U-41812025-05-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001123847582041-05-17U-39802025-08-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001123847582041-05-17U-41612025-08-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001116033632041-05-25Drug substance, Drug product2023-12-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001119511012041-07-15U-38952024-05-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001124537262041-07-15U-43002025-11-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08N218276-001100936632034-07-14U-41612024-09-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-001100936632034-07-14U-39802024-09-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-00196829682034-07-14Drug substance, Drug product2023-12-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-001117239012038-08-30U-39802024-09-046a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-001122854222038-08-30U-41812025-05-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-001116033632041-05-25Drug substance, Drug product2023-12-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-001119511012041-07-15U-38952024-05-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-001100936632034-07-14U-39802024-09-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-00196829682034-07-14Drug substance, Drug product2023-12-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-001117239012038-08-30U-39802024-09-04fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-001116033632041-05-25Drug substance, Drug product2023-12-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-001119511012041-07-15U-38952024-05-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-001100936632034-07-14U-39802024-09-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-00196829682034-07-14Drug substance, Drug product2023-12-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-001117239012038-08-30U-39802024-09-04b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-001116033632041-05-25Drug substance, Drug product2023-12-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-001119511012041-07-15U-38952024-05-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N218276-001100936632034-07-14U-39802024-09-0403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N218276-00196829682034-07-14Drug substance, Drug product2023-12-1803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N218276-001117239012038-08-30U-39802024-09-0403ed91905a0d…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 50 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N218276-001I-9492027-08-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001I-9632028-03-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001NCE2028-12-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N218276-001ODE-4562030-12-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001I-9492027-08-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001I-9632028-03-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001NCE2028-12-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N218276-001ODE-4562030-12-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08N218276-001I-9492027-08-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-001I-9632028-03-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-001NCE2028-12-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08N218276-001ODE-4562030-12-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-001I-9492027-08-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-001NCE2028-12-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N218276-001ODE-4562030-12-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-001I-9492027-08-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-001NCE2028-12-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N218276-001ODE-4562030-12-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N218276-001I-9492027-08-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N218276-001NCE2028-12-0503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N218276-001ODE-4562030-12-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N218276-001I-9492027-08-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N218276-001NCE2028-12-052680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N218276-001ODE-4562030-12-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N218276-001I-9492027-08-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N218276-001NCE2028-12-055bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N218276-001ODE-4562030-12-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N218276-001I-9492027-08-07d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N218276-001NCE2028-12-05d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N218276-001ODE-4562030-12-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N218276-001I-9492027-08-07d06236e962d9…
2024-10-29 15:01 UTC2024-10N218276-001NCE2028-12-05d06236e962d9…
2024-10-29 15:01 UTC2024-10N218276-001ODE-4562030-12-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N218276-001NCE2028-12-0579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N218276-001ODE-4562030-12-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N218276-001NCE2028-12-05301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N218276-001ODE-4562030-12-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N218276-001NCE2028-12-051e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N218276-001ODE-4562030-12-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05N218276-001NCE2028-12-058072bd15b7f6…

Additional Listing Data#

Finished product
Yes
Brand name base
FABHALTA
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
IPTACOPAN HYDROCHLORIDE200 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
XW5CK7C6YHInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2671074Internal RxNorm lookup
2671080Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a76b5845-6e21-4d3b-ad07-cd8df1b60beeAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
2098f44a-7b07-4419-8818-6f745bc41537Product name120241218

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0078-1189-20FABHALTA60 in 1 BOTTLECAPSULE604

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0078-1189-20EA - Each0078-1189216ede8f-d701-42b4-802a-750aa13ed2da12024-01-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0078-1189FABHALTA (IPTACOPAN) CAPSULE [NOVARTIS PHARMACEUTICALS CORPORATION]4Current NDC, 1 package rows20250323_a76b5845-6e21-4d3b-ad07-cd8df1b60bee.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
FABHALTAIPTACOPANNovartis Pharmaceuticals Corporationa76b5845-6e21-4d3b-ad07-cd8df1b60bee2026-07-16Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 218276
application number: NDA218276
ndc (product): 0078-1189

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2671080FABHALTA 200 MG Oral CapsulePSNa76b5845-6e21-4d3b-ad07-cd8df1b60bee4
2671074iptacopan 200 MG Oral CapsulePSNa76b5845-6e21-4d3b-ad07-cd8df1b60bee4
2671080iptacopan 200 MG Oral Capsule [Fabhalta]SBDa76b5845-6e21-4d3b-ad07-cd8df1b60bee4
2671074iptacopan 200 MG Oral CapsuleSCDa76b5845-6e21-4d3b-ad07-cd8df1b60bee4
2671080Fabhalta 200 MG (as iptacopan hydrochloride 225.8 MG) Oral CapsuleSYa76b5845-6e21-4d3b-ad07-cd8df1b60bee4
2671080Fabhalta 200 MG Oral CapsuleSYa76b5845-6e21-4d3b-ad07-cd8df1b60bee4
2671074iptacopan 200 MG (as iptacopan hydrochloride 225.8 MG) Oral CapsuleSYa76b5845-6e21-4d3b-ad07-cd8df1b60bee4

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
0078-1189-200007811892060 CAPSULE in 1 BOTTLE (0078-1189-20) 60 capsule2023-12-05NoNoCurrent