Tobramycin

Product NDC
0093-4085
11-digit product format
000934085
Labeler code
0093
Product ID
0093-4085_2aeb6242-a55e-4e45-96df-f2d26616e167
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Tobramycin
Dosage form
SOLUTION
Route
RESPIRATORY (INHALATION)
Labeler
Teva Pharmaceuticals USA, Inc.
Application
ANDA091589
Marketing category
ANDA
Marketing start
2013-11-19
Substance
TOBRAMYCIN
Active strength
300 mg/5mL
Pharmacologic classes
Aminoglycoside Antibacterial [EPC], Aminoglycosides [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A091589-001TOBRAMYCINTOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A091589-001AN

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-1031067a03dcf5…
2025-08-23 18:47 UTC2025-08A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-106a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-1003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-102680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-105bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-1079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-101e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-108072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-105c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-105d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-104b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-1074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-1087673890dc5c…
2021-03-12 10:30 UTC2021-03A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-105aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-108869cabd3fbd…
2020-11-12 02:37 UTC2020-11A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10c0c555d07b60…
2019-12-14 00:12 UTC2019-12A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-103f01610625f2…
2019-09-15 20:21 UTC2019-09A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10b00525d2431f…
2019-07-19 19:46 UTC2019-07A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-106a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-101c564ffb4f44…
2023-12-20 04:57 UTC2023-12A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-109b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-103f0d92c62455…
2023-05-13 08:27 UTC2023-05A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10053a50430f4f…
2023-01-26 05:58 UTC2023-01A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-103bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-103a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A091589-001TOBRAMYCIN300MG/5MLSOLUTION / INHALATIONAN2013-10-10cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A091589-001AN1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A091589-001AN131067a03dcf5…
2025-08-23 18:47 UTC2025-08A091589-001AN16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A091589-001AN1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A091589-001AN1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A091589-001AN103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A091589-001AN12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A091589-001AN15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A091589-001AN1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A091589-001AN1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A091589-001AN179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A091589-001AN1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A091589-001AN11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A091589-001AN18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A091589-001AN15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A091589-001AN15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A091589-001AN14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A091589-001AN174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A091589-001AN1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A091589-001AN1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A091589-001AN187673890dc5c…
2021-03-12 10:30 UTC2021-03A091589-001AN15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A091589-001AN18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A091589-001AN1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A091589-001AN13f01610625f2…
2019-09-15 20:21 UTC2019-09A091589-001AN1b00525d2431f…
2019-07-19 19:46 UTC2019-07A091589-001AN1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A091589-001AN16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A091589-001AN11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A091589-001AN1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A091589-001AN1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A091589-001AN19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A091589-001AN1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A091589-001AN13f0d92c62455…
2023-05-13 08:27 UTC2023-05A091589-001AN1053a50430f4f…
2023-01-26 05:58 UTC2023-01A091589-001AN13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A091589-001AN13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A091589-001AN1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A091589-001AN1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A091589-001AN1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Tobramycin
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TOBRAMYCIN300 mg/5mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
VZ8RRZ51VKInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
348719Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c5f65e5b-c851-45da-a0e8-215d9a4e6ad3Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
f297c7c1-845a-4369-8c02-c51b92d6ae8eProduct name320240725
551d952d-4ce2-24f0-9ab0-630ad9aae596Product name220231211
941f67d9-7f03-56d2-750c-36de24f654dbProduct name320221117
9cfa145f-dbe9-bc02-83c2-692786ef6676Product name920210928
2f9713b8-5e7e-bbcc-b364-1b2c27a63796Product name420210903
32a533bc-01c7-2b9f-bbf7-ecfb0d964277Product name420210625
9f5124fb-08b0-4c3e-8e12-a1a6ff310cbaProduct name120150309
745a62af-e1c0-4ca3-6d6e-2b6455b903beProduct name120140508
9ea85abb-fa68-5da6-ab60-2c7eef579000Product name120140508
aa1cd319-ece7-51f7-3a9d-52a64f5f4e81Product name120140508
d029211e-5e6b-725f-3696-ac6ff77da222Product name120140508
ef5b7aed-2b01-3ba8-5a1c-3bc9c9f03bb1Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0093-4085-63Tobramycin5 mL in 1 AMPULESOLUTION511
0093-4085-63Tobramycin56 in 1 CARTONSOLUTION5611

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0093-4085-63ML - Milliliter0093-4085e5ae01b3-9864-4471-8184-79489b693d3a12013-12-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
TOBRAMYCINACTIVE INGREDIENTVZ8RRZ51VKTOBRAMYCIN SOLUTION [TEVA PHARMACEUTICALS USA INC]2
TOBRAMYCINACTIVE MOIETYVZ8RRZ51VKTOBRAMYCIN SOLUTION [TEVA PHARMACEUTICALS USA INC]2
NITROGENINACTIVE INGREDIENTN762921K75TOBRAMYCIN SOLUTION [TEVA PHARMACEUTICALS USA INC]2
SODIUM CHLORIDEINACTIVE INGREDIENT451W47IQ8XTOBRAMYCIN SOLUTION [TEVA PHARMACEUTICALS USA INC]2
SODIUM HYDROXIDEINACTIVE INGREDIENT55X04QC32ITOBRAMYCIN SOLUTION [TEVA PHARMACEUTICALS USA INC]2
SULFURIC ACIDINACTIVE INGREDIENTO40UQP6WCFTOBRAMYCIN SOLUTION [TEVA PHARMACEUTICALS USA INC]2
WATERINACTIVE INGREDIENT059QF0KO0RTOBRAMYCIN SOLUTION [TEVA PHARMACEUTICALS USA INC]2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0093-4085TOBRAMYCIN SOLUTION [TEVA PHARMACEUTICALS USA, INC.]9Current NDC, Legacy NDC, 2 package rows20250226_c5f65e5b-c851-45da-a0e8-215d9a4e6ad3.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TobramycinTOBRAMYCINTeva Pharmaceuticals USA, Inc.c5f65e5b-c851-45da-a0e8-215d9a4e6ad32023-10-31Warnings, Adverse reactionsExact identifier
application applno (ANDA): 091589
application number: ANDA091589
ndc (product): 0093-4085

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
348719tobramycin 300 MG in 5 ML Inhalation SolutionPSNc5f65e5b-c851-45da-a0e8-215d9a4e6ad311
348719tobramycin 60 MG/ML Inhalation SolutionSCDc5f65e5b-c851-45da-a0e8-215d9a4e6ad311
348719tobramycin 300 MG per 5 ML Inhalation SolutionSYc5f65e5b-c851-45da-a0e8-215d9a4e6ad311

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0093-4085-630009340856356 AMPULE in 1 CARTON (0093-4085-63) / 5 mL in 1 AMPULE56 ampule2013-11-190000-00-00NoNoCurrent