THEOPHYLLINE

Product NDC
0121-0820
11-digit product format
001210820
Labeler code
0121
Product ID
0121-0820_895f63e5-665b-4227-8e44-6971ba5ce294
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
THEOPHYLLINE
Dosage form
SOLUTION
Route
ORAL
Labeler
PAI Holdings, LLC dba PAI Pharma
Application
ANDA206344
Marketing category
ANDA
Marketing start
2016-12-16
Substance
THEOPHYLLINE
Active strength
80 mg/15mL
Pharmacologic classes
Methylxanthine [EPC], Xanthines [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A206344-001THEOPHYLLINETHEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALRS2016-12-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALRS2016-12-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-1679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-161e350fbaab3a…
2024-05-31 18:47 UTC2024-05A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-168072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-165c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-165d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-164b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-1674a2ff9319b5…
2022-03-09 01:35 UTC2022-03A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-1687673890dc5c…
2021-03-12 10:30 UTC2021-03A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-165aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-168869cabd3fbd…
2020-11-12 02:37 UTC2020-11A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16c0c555d07b60…
2019-12-14 00:12 UTC2019-12A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-163f01610625f2…
2019-09-15 20:21 UTC2019-09A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16b00525d2431f…
2019-07-19 19:46 UTC2019-07A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-166a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-161c564ffb4f44…
2023-12-20 04:57 UTC2023-12A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-169b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-163f0d92c62455…
2023-05-13 08:27 UTC2023-05A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16053a50430f4f…
2023-01-26 05:58 UTC2023-01A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-163bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-163a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A206344-001THEOPHYLLINE80MG/15MLSOLUTION, ELIXIR / ORALAA2016-12-16cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206344-001AA131067a03dcf5…
2025-08-23 18:47 UTC2025-08A206344-001AA16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206344-001AA1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206344-001AA1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206344-001AA103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206344-001AA12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206344-001AA15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206344-001AA1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A206344-001AA1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206344-001AA179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206344-001AA1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206344-001AA11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A206344-001AA18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206344-001AA15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A206344-001AA15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A206344-001AA14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A206344-001AA174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A206344-001AA1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A206344-001AA1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A206344-001AA187673890dc5c…
2021-03-12 10:30 UTC2021-03A206344-001AA15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A206344-001AA18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A206344-001AA1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A206344-001AA13f01610625f2…
2019-09-15 20:21 UTC2019-09A206344-001AA1b00525d2431f…
2019-07-19 19:46 UTC2019-07A206344-001AA1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A206344-001AA16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A206344-001AA11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A206344-001AA1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A206344-001AA1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A206344-001AA19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A206344-001AA1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A206344-001AA13f0d92c62455…
2023-05-13 08:27 UTC2023-05A206344-001AA1053a50430f4f…
2023-01-26 05:58 UTC2023-01A206344-001AA13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A206344-001AA13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A206344-001AA1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A206344-001AA1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A206344-001AA1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
THEOPHYLLINE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
THEOPHYLLINE80 mg/15mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
C137DTR5RGInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
313306Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
32b9780f-c46f-4e0f-9641-2cab60600e6eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d1d07c79-5983-427d-b6f5-df0550dcc598Product name420250325
e2db08c6-133f-4f4f-afb4-e90a2418d6f6Product name120230320
ce6d5c06-3ae0-18a6-d5b3-8cd3cc0f8906Product name720210625
f52be47f-7aa7-46c0-b1fa-50c18dd50206Product name120201029
11ed6f83-cdd2-4637-8379-b1a1d3ae3cdeProduct name120181101
86c45a79-b9f0-4476-a27c-6e10db098497Product name120180125
7b1e3dc0-e6b1-4d5d-943b-99fdd948b5a2Product name120170302
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0121-0820-04THEOPHYLLINE118 mL in 1 BOTTLESOLUTION1189
0121-0820-16THEOPHYLLINE473 mL in 1 BOTTLESOLUTION4739

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0121-0820-16ML - Milliliter0121-0820f944f03e-35f9-4f45-8b91-a3f410069f1612017-06-15

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0121-0820THEOPHYLLINE SOLUTION [PAI HOLDINGS, LLC DBA PAI PHARMA]9Current NDC, Legacy NDC, 2 package rows20241121_32b9780f-c46f-4e0f-9641-2cab60600e6e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
THEOPHYLLINETHEOPHYLLINEPAI Holdings, LLC dba PAI Pharma32b9780f-c46f-4e0f-9641-2cab60600e6e2024-11-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 206344
application number: ANDA206344
ndc (product): 0121-0820

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
313306theophylline 80 MG in 15 mL Oral SolutionPSN32b9780f-c46f-4e0f-9641-2cab60600e6e9
313306theophylline 5.33 MG/ML Oral SolutionSCD32b9780f-c46f-4e0f-9641-2cab60600e6e9
313306theophylline 100 MG per 18.75 ML Oral SolutionSY32b9780f-c46f-4e0f-9641-2cab60600e6e9
313306theophylline 80 MG per 15 ML Oral SolutionSY32b9780f-c46f-4e0f-9641-2cab60600e6e9

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0121-0820-0400121082004118 mL in 1 BOTTLE (0121-0820-04) 118 ml2016-12-160000-00-00NoNoCurrent
0121-0820-1600121082016473 mL in 1 BOTTLE (0121-0820-16) 473 ml2016-12-160000-00-00NoNoCurrent