Lidocaine Hydrochloride

Product NDC
0121-0972
Requested package NDC
0121-0972-51
11-digit product format
001210972
Labeler code
0121
Product ID
0121-0972_498bed31-acd1-4f21-bb38-65ee6db6c573
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Lidocaine Hydrochloride
Dosage form
SOLUTION
Route
TOPICAL
Labeler
PAI Holdings, LLC dba PAI Pharma
Application
ANDA204494
Marketing category
ANDA
Marketing start
2023-07-31
Substance
LIDOCAINE HYDROCHLORIDE
Active strength
40 mg/mL
Pharmacologic classes
Amide Local Anesthetic [EPC], Amides [CS], Antiarrhythmic [EPC], Local Anesthesia [PE]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A204494-001LIDOCAINE HYDROCHLORIDELIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A204494-001AT

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-1231067a03dcf5…
2025-08-23 18:47 UTC2025-08A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-126a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-1203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-122680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-125bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-1279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-121e350fbaab3a…
2024-05-31 18:47 UTC2024-05A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-128072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-125c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-125d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-124b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-1274a2ff9319b5…
2022-03-09 01:35 UTC2022-03A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-1287673890dc5c…
2021-03-12 10:30 UTC2021-03A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-125aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-128869cabd3fbd…
2020-11-12 02:37 UTC2020-11A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12c0c555d07b60…
2019-12-14 00:12 UTC2019-12A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-123f01610625f2…
2019-09-15 20:21 UTC2019-09A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12b00525d2431f…
2019-07-19 19:46 UTC2019-07A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-126a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-121c564ffb4f44…
2023-12-20 04:57 UTC2023-12A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-129b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-123f0d92c62455…
2023-05-13 08:27 UTC2023-05A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12053a50430f4f…
2023-01-26 05:58 UTC2023-01A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-123bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-123a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A204494-001LIDOCAINE HYDROCHLORIDE4%SOLUTION / TOPICALAT2014-03-12cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A204494-001AT1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A204494-001AT131067a03dcf5…
2025-08-23 18:47 UTC2025-08A204494-001AT16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A204494-001AT1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A204494-001AT1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A204494-001AT103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A204494-001AT12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A204494-001AT15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A204494-001AT1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A204494-001AT1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A204494-001AT179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A204494-001AT1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A204494-001AT11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A204494-001AT18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A204494-001AT15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A204494-001AT15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A204494-001AT14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A204494-001AT174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A204494-001AT1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A204494-001AT1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A204494-001AT187673890dc5c…
2021-03-12 10:30 UTC2021-03A204494-001AT15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A204494-001AT18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A204494-001AT1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A204494-001AT13f01610625f2…
2019-09-15 20:21 UTC2019-09A204494-001AT1b00525d2431f…
2019-07-19 19:46 UTC2019-07A204494-001AT1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A204494-001AT16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A204494-001AT11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A204494-001AT1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A204494-001AT1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A204494-001AT19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A204494-001AT1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A204494-001AT13f0d92c62455…
2023-05-13 08:27 UTC2023-05A204494-001AT1053a50430f4f…
2023-01-26 05:58 UTC2023-01A204494-001AT13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A204494-001AT13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A204494-001AT1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A204494-001AT1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A204494-001AT1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Lidocaine Hydrochloride
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LIDOCAINE HYDROCHLORIDE40 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
V13007Z41AInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1010878Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9920daef-b156-4a14-b641-f714191ffb5cAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
070fbed5-7088-434a-a7ce-f2a64d8d40acProduct name220260107
bee66ce1-adb7-9d3b-67d9-582e4c54e80fProduct name520250819
860a93dc-4863-49cc-b284-6bbe8191bc48Product name420250214
eaba870a-6a9d-442e-8643-87b3f558a451Product name120250117
9b4cf230-fd05-41d5-98c6-5db9ecb27b86Product name120230117
7d755fa1-1087-4dcd-98f0-6d4bba479a57Product name320210602
aed701d5-9c75-dfaf-7154-cde46179faeaProduct name920200313
fa8b5901-e681-426f-82fe-54f6d81ec698Product name420180619
332d03e4-aa24-4b11-841a-02bf41081920Product name120171221
c08ab52f-2fc8-4409-9d9f-ed8edc0bd070Product name120171221
68ed98f8-24c2-44a0-944a-6d36e82ce25aProduct name120141222
1cd42bc2-a430-c72b-636d-991b235fbf80Product name120140508
49fa150c-f0de-cce7-3d9c-993ed81c5698Product name120140508
4d7ae718-ed00-bae8-2abe-9eaec1eef7ffProduct name120140508
9137811f-f279-8640-5aeb-99fa2145d64dProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0121-0972-51Lidocaine Hydrochloride1 in 1 CARTONSOLUTION18
0121-0972-51Lidocaine Hydrochloride50 mL in 1 BOTTLE, GLASSSOLUTION508

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0121-0972-51ML - Milliliter0121-09722204d837-ff6d-4ad4-86f7-b0b8a983ff3712023-08-08

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0121-0972LIDOCAINE HYDROCHLORIDE SOLUTION [PAI HOLDINGS, LLC DBA PAI PHARMA]5Current NDC, 2 package rows20241116_9920daef-b156-4a14-b641-f714191ffb5c.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Lidocaine HydrochlorideLIDOCAINE HYDROCHLORIDEPAI Holdings, LLC dba PAI Pharma9920daef-b156-4a14-b641-f714191ffb5c2026-04-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 204494
application number: ANDA204494
ndc (package): 0121-0972-51
ndc (product): 0121-0972
ndc11 (package): 00121097251
Lidocaine HydrochlorideLIDOCAINE HYDROCHLORIDEMcKesson Corporation dba SKY Packaging903cd7bd-6c3d-4068-bb24-e91b1ca1393d2024-12-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 204494
application number: ANDA204494

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1010878lidocaine HCl 4 % Mucous Membrane Topical SolutionPSN9920daef-b156-4a14-b641-f714191ffb5c8
1010878lidocaine hydrochloride 40 MG/ML Mucous Membrane Topical SolutionSCD9920daef-b156-4a14-b641-f714191ffb5c8
1010878lidocaine hydrochloride 4 % Mucous Membrane Topical SolutionSY9920daef-b156-4a14-b641-f714191ffb5c8
1010878lidocaine hydrochloride 4 % Oromucosal SolutionSY9920daef-b156-4a14-b641-f714191ffb5c8

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
0121-0972-51001210972511 BOTTLE, GLASS in 1 CARTON (0121-0972-51) / 50 mL in 1 BOTTLE, GLASS2023-07-31NoNoCurrent