Thiotepa

Product NDC
0143-9292
11-digit product format
001439292
Labeler code
0143
Product ID
0143-9292_f18a13d2-83c0-42a1-8980-60b228c23ab9
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Thiotepa
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRACAVITARY; INTRAVENOUS; INTRAVESICAL
Labeler
Hikma Pharmaceuticals USA Inc.
Application
ANDA211755
Marketing category
ANDA
Marketing start
2023-09-29
Substance
THIOTEPA
Active strength
100 mg/1
Pharmacologic classes
Alkylating Activity [MoA], Alkylating Drug [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211755-001THIOTEPATHIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A211755-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-058072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-059b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211755-001THIOTEPA100MG/VIALPOWDER / INTRACAVITARY, INTRAVENOUS, INTRAVESICALAP2023-09-05a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A211755-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211755-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211755-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211755-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211755-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211755-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211755-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211755-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211755-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211755-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211755-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A211755-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A211755-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A211755-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A211755-001AP18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A211755-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A211755-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A211755-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A211755-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A211755-001AP19b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211755-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Thiotepa
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
THIOTEPA100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
905Z5W3GKHInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1660004Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9ae8063c-ba28-4da2-a94c-8e1a5f75e4b3Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b9d03845-c04b-46cb-bb7e-9c6cffe3c163Product name420250618
d48e4a3f-d6a3-47a1-9357-dd5939f6049dProduct name120250227
d4b5276b-261e-446e-ba03-7cf7bbc1d8afProduct name320220718

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0143-9292-01Thiotepa1 in 1 VIALINJECTION, POWDER, LYOPHILIZED,13
0143-9292-01Thiotepa1 in 1 BOX, UNIT-DOSEINJECTION, POWDER, LYOPHILIZED,13

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0143-9292-01EA - Each0143-929262015df6-ab4c-4b74-a133-b4a8d09eda3612024-10-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0143-9292THIOTEPA INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [HIKMA PHARMACEUTICALS USA INC.]3Current NDC, 2 package rows20230929_9ae8063c-ba28-4da2-a94c-8e1a5f75e4b3.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ThiotepaTHIOTEPAHikma Pharmaceuticals USA Inc.9ae8063c-ba28-4da2-a94c-8e1a5f75e4b32023-05-31Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211755
application number: ANDA211755
ndc (product): 0143-9292

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1660004thiotepa 100 MG InjectionPSN9ae8063c-ba28-4da2-a94c-8e1a5f75e4b33
1660004thiotepa 100 MG InjectionSCD9ae8063c-ba28-4da2-a94c-8e1a5f75e4b33
1660004TSPA 100 MG InjectionSY9ae8063c-ba28-4da2-a94c-8e1a5f75e4b33

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
0143-9292-01001439292011 VIAL in 1 BOX, UNIT-DOSE (0143-9292-01) / 1 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION in 1 VIAL1 vial2023-09-29NoNoCurrent