ketoconazole

Product NDC
0168-0099
11-digit product format
001680099
Labeler code
0168
Product ID
0168-0099_6eaf555f-3e9c-4811-ae1f-66afda8b2b11
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
ketoconazole
Dosage form
CREAM
Route
TOPICAL
Labeler
E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC
Application
ANDA076294
Marketing category
ANDA
Marketing start
2004-04-28
Substance
KETOCONAZOLE
Active strength
20 mg/g
Pharmacologic classes
Azole Antifungal [EPC], Azoles [CS], Cytochrome P450 3A4 Inhibitors [MoA], Cytochrome P450 3A5 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076294-001KETOCONAZOLEKETOCONAZOLE2%CREAM / TOPICALAB2004-04-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A076294-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-2887673890dc5c…
2021-03-12 10:30 UTC2021-03A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-283f01610625f2…
2019-09-15 20:21 UTC2019-09A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28b00525d2431f…
2019-07-19 19:46 UTC2019-07A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-283f0d92c62455…
2023-05-13 08:27 UTC2023-05A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28053a50430f4f…
2023-01-26 05:58 UTC2023-01A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-283bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-283a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A076294-001KETOCONAZOLE2%CREAM / TOPICALAB2004-04-28cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A076294-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076294-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A076294-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076294-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076294-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076294-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076294-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076294-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076294-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076294-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076294-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076294-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076294-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076294-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076294-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076294-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076294-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076294-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076294-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076294-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076294-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A076294-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076294-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076294-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076294-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A076294-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A076294-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076294-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076294-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076294-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076294-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076294-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076294-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076294-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A076294-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A076294-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076294-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076294-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076294-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A076294-001AB1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
ketoconazole
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
KETOCONAZOLE20 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
R9400W927IInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
203088Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
cad7c647-34a9-4e4e-83b3-8d78e58f588fAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
fd9dd88b-5db8-6370-b47e-37f6c9b1c5d5Product name220250331
1e18fb2e-aeff-8efe-93be-5a5f7be8faa2Product name220211209
8bc3781f-20ed-678b-44a7-a981e693c65fProduct name220211209
ff3a8c91-648c-300b-467e-10703f514265Product name220180809
152a96a4-36b6-f5b1-d4e6-9a500e06bbf3Product name120140508

FDA-Initiated Inactive NDC Indexing#

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0168-0099-15ketoconazole15 g in 1 TUBECREAM158
0168-0099-15ketoconazole1 in 1 CARTONCREAM18
0168-0099-30ketoconazole1 in 1 CARTONCREAM18
0168-0099-30ketoconazole30 g in 1 TUBECREAM308
0168-0099-60ketoconazole1 in 1 CARTONCREAM18
0168-0099-60ketoconazole60 g in 1 TUBECREAM608

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0168-0099-15GM - Gram0168-00999394d72e-bc33-4248-b3fe-3b2c6d14bb6612012-07-24
0168-0099-30GM - Gram0168-009926999d10-ab4e-4d54-a033-2f523faacf3a12012-07-24
0168-0099-60GM - Gram0168-0099f3dce791-6e71-4e4b-8765-fa2e486bd7b612012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ketoconazoleACTIVE INGREDIENTR9400W927IKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
ketoconazoleACTIVE MOIETYR9400W927IKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
cetyl alcoholINACTIVE INGREDIENT936JST6JCNKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
isopropyl myristateINACTIVE INGREDIENT0RE8K4LNJSKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
polysorbate 60INACTIVE INGREDIENTCAL22UVI4MKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
polysorbate 80INACTIVE INGREDIENT6OZP39ZG8HKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
propylene glycolINACTIVE INGREDIENT6DC9Q167V3KETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
sodium sulfiteINACTIVE INGREDIENTVTK01UQK3GKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
sorbitan monostearateINACTIVE INGREDIENTNVZ4I0H58XKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
stearyl alcoholINACTIVE INGREDIENT2KR89I4H1YKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
waterINACTIVE INGREDIENT059QF0KO0RKETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]3
KETOCONAZOLEACTIVE INGREDIENTR9400W927IKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
KETOCONAZOLEACTIVE INGREDIENTR9400W927IKETOCONAZOLE CREAM [DIRECT RX]1
KETOCONAZOLEACTIVE MOIETYR9400W927IKETOCONAZOLE CREAM [DIRECT RX]1
KETOCONAZOLEACTIVE MOIETYR9400W927IKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
cetyl alcoholINACTIVE INGREDIENT936JST6JCNKETOCONAZOLE CREAM [DIRECT RX]1
CETYL ALCOHOLINACTIVE INGREDIENT936JST6JCNKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
ISOPROPYL MYRISTATEINACTIVE INGREDIENT0RE8K4LNJSKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
isopropyl myristateINACTIVE INGREDIENT0RE8K4LNJSKETOCONAZOLE CREAM [DIRECT RX]1
POLYSORBATE 60INACTIVE INGREDIENTCAL22UVI4MKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
polysorbate 60INACTIVE INGREDIENTCAL22UVI4MKETOCONAZOLE CREAM [DIRECT RX]1
POLYSORBATE 80INACTIVE INGREDIENT6OZP39ZG8HKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
polysorbate 80INACTIVE INGREDIENT6OZP39ZG8HKETOCONAZOLE CREAM [DIRECT RX]1
propylene glycolINACTIVE INGREDIENT6DC9Q167V3KETOCONAZOLE CREAM [DIRECT RX]1
PROPYLENE GLYCOLINACTIVE INGREDIENT6DC9Q167V3KETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
sodium sulfiteINACTIVE INGREDIENTVTK01UQK3GKETOCONAZOLE CREAM [DIRECT RX]1
SODIUM SULFITEINACTIVE INGREDIENTVTK01UQK3GKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
SORBITAN MONOSTEARATEINACTIVE INGREDIENTNVZ4I0H58XKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
sorbitan monostearateINACTIVE INGREDIENTNVZ4I0H58XKETOCONAZOLE CREAM [DIRECT RX]1
STEARYL ALCOHOLINACTIVE INGREDIENT2KR89I4H1YKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1
stearyl alcoholINACTIVE INGREDIENT2KR89I4H1YKETOCONAZOLE CREAM [DIRECT RX]1
waterINACTIVE INGREDIENT059QF0KO0RKETOCONAZOLE CREAM [DIRECT RX]1
WATERINACTIVE INGREDIENT059QF0KO0RKETOCONAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0168-0099KETOCONAZOLE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]7Current NDC, Legacy NDC, 6 package rows20211020_cad7c647-34a9-4e4e-83b3-8d78e58f588f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ketoconazoleKETOCONAZOLEE. Fougera & Co. a division of Fougera Pharmaceuticals, LLCcad7c647-34a9-4e4e-83b3-8d78e58f588f2026-01-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 076294
application number: ANDA076294
ndc (product): 0168-0099

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
203088ketoconazole 2 % Topical CreamPSNcad7c647-34a9-4e4e-83b3-8d78e58f588f8
203088ketoconazole 20 MG/ML Topical CreamSCDcad7c647-34a9-4e4e-83b3-8d78e58f588f8
203088ketoconazole 2 % Topical CreamSYcad7c647-34a9-4e4e-83b3-8d78e58f588f8
203088ketoconazole 2 % Topical CreamPSN720927e8-7b3f-4ed9-9893-1be1ea122dc83
203088ketoconazole 20 MG/ML Topical CreamSCD720927e8-7b3f-4ed9-9893-1be1ea122dc83
203088ketoconazole 2 % Topical CreamSY720927e8-7b3f-4ed9-9893-1be1ea122dc83
203088ketoconazole 2 % Topical CreamPSN1c062a81-e366-4d71-e063-6294a90abfd21
203088ketoconazole 2 % Topical CreamPSNe46c7380-a943-4dfd-8953-6402272cf6ff1
203088ketoconazole 20 MG/ML Topical CreamSCD1c062a81-e366-4d71-e063-6294a90abfd21
203088ketoconazole 20 MG/ML Topical CreamSCDe46c7380-a943-4dfd-8953-6402272cf6ff1
203088ketoconazole 2 % Topical CreamSY1c062a81-e366-4d71-e063-6294a90abfd21
203088ketoconazole 2 % Topical CreamSYe46c7380-a943-4dfd-8953-6402272cf6ff1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0168-0099-15001680099151 TUBE in 1 CARTON (0168-0099-15) / 15 g in 1 TUBE1 tube2004-04-280000-00-00NoNoCurrent
0168-0099-30001680099301 TUBE in 1 CARTON (0168-0099-30) / 30 g in 1 TUBE1 tube2004-04-280000-00-00NoNoCurrent
0168-0099-60001680099601 TUBE in 1 CARTON (0168-0099-60) / 60 g in 1 TUBE1 tube2004-04-280000-00-00NoNoCurrent