Metronidazole

Product NDC
0168-0323
11-digit product format
001680323
Labeler code
0168
Product ID
0168-0323_111e50c5-83e4-4817-8c3f-ed7416de2dd3
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Metronidazole
Dosage form
CREAM
Route
TOPICAL
Labeler
Fougera Pharmaceuticals, LLC
Application
ANDA076408
Marketing category
ANDA
Marketing start
2004-05-28
Substance
METRONIDAZOLE
Active strength
7.5 mg/g
Pharmacologic classes
Nitroimidazole Antimicrobial [EPC], Nitroimidazoles [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 6 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2022-04-09 23:13 UTC · source 2022-04-08excluded productproduct86f5da6cb304…a595104c45d7…
2022-04-09 23:13 UTC · source 2022-04-08excluded packagepackage0168-0323-4686f5da6cb304…a595104c45d7…
2022-04-04 05:40 UTC · source 2022-04-01excluded productproductbd6a592717d7…303034d00443…
2022-04-04 05:40 UTC · source 2022-04-01excluded packagepackage0168-0323-46bd6a592717d7…303034d00443…
2021-12-27 23:28 UTC · source 2021-12-27excluded productproduct8dfbde2a14a4…c9ff85d89658…
2021-12-27 23:28 UTC · source 2021-12-27excluded packagepackage0168-0323-468dfbde2a14a4…c9ff85d89658…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A076408-001METRONIDAZOLEMETRONIDAZOLE0.75%CREAM / TOPICALABRS2004-05-28

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A076408-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A076408-001METRONIDAZOLE0.75%CREAM / TOPICALABRS2004-05-28caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A076408-001METRONIDAZOLE0.75%CREAM / TOPICALABRS2004-05-28011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076408-001METRONIDAZOLE0.75%CREAM / TOPICALABRS2004-05-2831067a03dcf5…
2025-08-23 18:47 UTC2025-08A076408-001METRONIDAZOLE0.75%CREAM / TOPICALABRS2004-05-286a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-2803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-282680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-285bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-2879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-281e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-288072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-285c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-285d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-284b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-2874a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-2887673890dc5c…
2021-03-12 10:30 UTC2021-03A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-285aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-288869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-283f01610625f2…
2019-09-15 20:21 UTC2019-09A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28b00525d2431f…
2019-07-19 19:46 UTC2019-07A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-286a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-281c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-289b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-283f0d92c62455…
2023-05-13 08:27 UTC2023-05A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28053a50430f4f…
2023-01-26 05:58 UTC2023-01A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-283bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-283a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076408-001METRONIDAZOLE0.75%CREAM / TOPICALAB2004-05-28e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A076408-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A076408-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A076408-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A076408-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A076408-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A076408-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A076408-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A076408-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A076408-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A076408-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A076408-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A076408-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A076408-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A076408-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A076408-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A076408-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A076408-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A076408-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A076408-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A076408-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A076408-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A076408-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A076408-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A076408-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A076408-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A076408-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A076408-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A076408-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A076408-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A076408-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A076408-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A076408-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A076408-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A076408-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A076408-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A076408-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A076408-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A076408-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A076408-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A076408-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
Metronidazole
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
METRONIDAZOLE7.5 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
140QMO216EInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
311678Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
43ed872b-63ac-4a22-9c9e-cc0e05bcc41eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
8ffb9b1d-3ed7-ba2e-677e-47d4d134fd55Product name520251024
7f6d14e0-4366-41bc-a4a9-b74c79a20e17Product name120250623
e6d321b0-0e5e-7da6-f043-92b6a91f00a1Product name520250515
e1aac33b-94ae-4ee9-905b-299f7263853bProduct name320250124
16642716-d28a-4f90-8dcb-3921cd8c8109Product name420240516
0be8e4ae-4d57-49f3-b3a9-e4728b4e8d15Product name120240313
f52be47f-7aa7-46c0-b1fa-50c18dd50206Product name120201029
444b3e50-f226-46ef-bfca-2e7035d140cdProduct name120190611
dea2eded-d1e7-46bb-9a3d-f8dc20de6277Product name120190408
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
a5070875-62bb-61e1-fd46-8f7054197a40Product name820180215
0add4de9-d152-3375-3390-1123dddc5e3dProduct name120140508
33ca0fcc-1011-92dc-50a9-a383683eed1eProduct name120140508
53f39d9f-cd3f-04e1-c668-d4580719d57dProduct name120140508
597b1cfd-7b31-5048-62be-ca5cd740da2fProduct name120140508
9869efd7-d6dd-0665-5b67-53adbe6ef15eProduct name120140508
a804000f-b74f-0b5d-d17b-aa767c286ddbProduct name120140508
a91ea265-6e02-c08f-93c8-686d54180529Product name120140508
ec2149b3-5c6d-5344-f757-c86411073075Product name120140508

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDCEffectiveActionDocumentIndexing SPLRelated label
0168-0323-462022-06-29C16284748780-1c7ccaba7-2a48-fd44-e053-dadaa90aa01bMETRONIDAZOLE TOPICAL CREAM 0.75%
0168-0323-462021-07-23C16284748780-1c7ccaba7-2a48-fd44-e053-dadaa90aa01bMETRONIDAZOLE TOPICAL CREAM 0.75%

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0168-0323-46Metronidazole45 g in 1 TUBECREAM4510

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0168-0323-46GM - Gram0168-03239e6face9-a69b-4e9c-b499-a9cc4cb04ec912012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
metronidazoleACTIVE INGREDIENT140QMO216EMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
metronidazoleACTIVE MOIETY140QMO216EMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
benzyl alcoholINACTIVE INGREDIENTLKG8494WBHMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
glycerinINACTIVE INGREDIENTPDC6A3C0OXMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
isopropyl palmitateINACTIVE INGREDIENT8CRQ2TH63MMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
lactic acidINACTIVE INGREDIENT33X04XA5ATMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
sodium hydroxideINACTIVE INGREDIENT55X04QC32IMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
sorbitolINACTIVE INGREDIENT506T60A25RMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
waterINACTIVE INGREDIENT059QF0KO0RMETRONIDAZOLE CREAM [E.FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]4
METRONIDAZOLEACTIVE INGREDIENT140QMO216EMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2
METRONIDAZOLEACTIVE MOIETY140QMO216EMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2
BENZYL ALCOHOLINACTIVE INGREDIENTLKG8494WBHMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2
GLYCERININACTIVE INGREDIENTPDC6A3C0OXMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2
ISOPROPYL PALMITATEINACTIVE INGREDIENT8CRQ2TH63MMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2
LACTIC ACIDINACTIVE INGREDIENT33X04XA5ATMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2
SODIUM HYDROXIDEINACTIVE INGREDIENT55X04QC32IMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2
SORBITOLINACTIVE INGREDIENT506T60A25RMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2
WATERINACTIVE INGREDIENT059QF0KO0RMETRONIDAZOLE CREAM [PHYSICIANS TOTAL CARE, INC.]2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0168-0323METRONIDAZOLE CREAM [FOUGERA PHARMACEUTICALS INC.]9Current NDC, Legacy NDC, 1 package rows20220701_43ed872b-63ac-4a22-9c9e-cc0e05bcc41e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MetronidazoleMETRONIDAZOLEFougera Pharmaceuticals, LLC43ed872b-63ac-4a22-9c9e-cc0e05bcc41e2026-01-28Adverse reactionsExact identifier
application applno (ANDA): 076408
application number: ANDA076408
ndc (product): 0168-0323
MetronidazoleMETRONIDAZOLEBryant Ranch Prepack38376be4-4bb3-4647-aedf-bb7bfef053e52024-02-29Adverse reactionsExact identifier
application applno (ANDA): 076408
application number: ANDA076408

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
311678metroNIDAZOLE 0.75 % Topical CreamPSN38376be4-4bb3-4647-aedf-bb7bfef053e5101
311678metronidazole 7.5 MG/ML Topical CreamSCD38376be4-4bb3-4647-aedf-bb7bfef053e5101
311678metronidazole 0.75 % Topical CreamSY38376be4-4bb3-4647-aedf-bb7bfef053e5101
311678metroNIDAZOLE 0.75 % Topical CreamPSN43ed872b-63ac-4a22-9c9e-cc0e05bcc41e10
311678metronidazole 7.5 MG/ML Topical CreamSCD43ed872b-63ac-4a22-9c9e-cc0e05bcc41e10
311678metronidazole 0.75 % Topical CreamSY43ed872b-63ac-4a22-9c9e-cc0e05bcc41e10
311678metroNIDAZOLE 0.75 % Topical CreamPSN33a06972-62b7-4131-81da-77ae692b48692
311678metronidazole 7.5 MG/ML Topical CreamSCD33a06972-62b7-4131-81da-77ae692b48692
311678metronidazole 0.75 % Topical CreamSY33a06972-62b7-4131-81da-77ae692b48692

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0168-0323-460016803234645 g in 1 TUBE (0168-0323-46) 45 g2004-05-280000-00-00NoNoCurrent