Spironolactone

Product NDC: 0228-2672
11-digit product format: 002282672
Labeler code: 0228
Product ID: 0228-2672_c2c9d105-84e7-4a04-807f-d236959c0742
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Spironolactone
Dosage form: TABLET, FILM COATED
Route: ORAL
Labeler: Actavis Pharma, Inc.
Application: ANDA040353
Marketing category: ANDA
Marketing start: 2007-01-03
Marketing end: 2020-09-30
Substance: SPIRONOLACTONE
Active strength: 50 mg/1
Pharmacologic classes: Aldosterone Antagonist [EPC],Aldosterone Antagonists [MoA]
NDC exclude flag: No
Listing certified through: 0000-00-00
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	0228-2672		D	Discontinued by firm	2026-08-11
excluded package	package	0228-2672	0228-2672-11	D	Discontinued by firm	2026-08-11
excluded package	package	0228-2672	0228-2672-50	D	Discontinued by firm	2026-08-11

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 36 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0228-2672-11	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0228-2672-50	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0228-2672-11	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0228-2672-50	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0228-2672-11	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0228-2672-50	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0228-2672-11	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0228-2672-50	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0228-2672-11	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0228-2672-50	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0228-2672-11	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0228-2672-50	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0228-2672-11	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0228-2672-50	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0228-2672-11	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0228-2672-50	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0228-2672-11	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0228-2672-50	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0228-2672-11	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0228-2672-50	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0228-2672-11	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0228-2672-50	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0228-2672-11	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0228-2672-50	`557ba5c1ecfa…`	`9c80585c8c6e…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	Approval date
A040353-001	SPIRONOLACTONE	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29
A040353-002	SPIRONOLACTONE	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29
A040353-003	SPIRONOLACTONE	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`301d65b070ca…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A040353-002	SPIRONOLACTONE	100MG	TABLET / ORAL	1999-07-29	`1e350fbaab3a…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A040353-003	SPIRONOLACTONE	25MG	TABLET / ORAL	2006-03-15	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A040353-001	SPIRONOLACTONE	50MG	TABLET / ORAL	1999-07-29	`8072bd15b7f6…`

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
d335cba1-5b36-51c8-120a-594ec9d05330	Product name	5	20251114
25f5e2cf-3572-477b-994c-aa692751e5a8	Product name	2	20250616
ed912195-5da0-0f2f-6f4b-3ef17710cbe3	Product name	1	20140508
f151007d-265d-9fbe-857d-1d44f1cb76ba	Product name	1	20140508

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0228-2672-11	EA - Each	0228-2672	d985b389-f4ec-4b5f-83c6-dbdb4addb785	1	2012-07-24
0228-2672-50	EA - Each	0228-2672	3cf7ce43-8ae9-4a0e-baf3-6beb36654321	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
SPIRONOLACTONE	ACTIVE INGREDIENT	27O7W4T232	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
SPIRONOLACTONE	ACTIVE MOIETY	27O7W4T232	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
CALCIUM SULFATE	INACTIVE INGREDIENT	WAT0DDB505	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
CROSPOVIDONE	INACTIVE INGREDIENT	68401960MK	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
DEXTROSE	INACTIVE INGREDIENT	IY9XDZ35W2	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
HYPROMELLOSES	INACTIVE INGREDIENT	3NXW29V3WO	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
MAGNESIUM STEARATE	INACTIVE INGREDIENT	70097M6I30	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
MALTODEXTRIN	INACTIVE INGREDIENT	7CVR7L4A2D	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
PEPPERMINT	INACTIVE INGREDIENT	V95R5KMY2B	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
POLYDEXTROSE	INACTIVE INGREDIENT	VH2XOU12IE	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
POLYETHYLENE GLYCOLS	INACTIVE INGREDIENT	3WJQ0SDW1A	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
POVIDONE K29/32	INACTIVE INGREDIENT	390RMW2PEQ	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
TITANIUM DIOXIDE	INACTIVE INGREDIENT	15FIX9V2JP	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
TRIACETIN	INACTIVE INGREDIENT	XHX3C3X673	SPIRONOLACTONE TABLET, FILM COATED [ACTAVIS PHARMA, INC.]	8
SPIRONOLACTONE	ACTIVE INGREDIENT	27O7W4T232	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
SPIRONOLACTONE	ACTIVE MOIETY	27O7W4T232	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
CALCIUM SULFATE	INACTIVE INGREDIENT	WAT0DDB505	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
CROSPOVIDONE	INACTIVE INGREDIENT	68401960MK	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
DEXTROSE	INACTIVE INGREDIENT	IY9XDZ35W2	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
HYPROMELLOSES	INACTIVE INGREDIENT	3NXW29V3WO	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
MAGNESIUM STEARATE	INACTIVE INGREDIENT	70097M6I30	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
MALTODEXTRIN	INACTIVE INGREDIENT	7CVR7L4A2D	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
PEPPERMINT	INACTIVE INGREDIENT	V95R5KMY2B	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
POLYDEXTROSE	INACTIVE INGREDIENT	VH2XOU12IE	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
POLYETHYLENE GLYCOL	INACTIVE INGREDIENT	3WJQ0SDW1A	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
POVIDONE	INACTIVE INGREDIENT	FZ989GH94E	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
TITANIUM DIOXIDE	INACTIVE INGREDIENT	15FIX9V2JP	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3
TRIACETIN	INACTIVE INGREDIENT	XHX3C3X673	SPIRONOLACTONE TABLET, FILM COATED [PHYSICIANS TOTAL CARE, INC.]	3

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
27O7W4T232	SPIRONOLACTONE	52-01-7	SPIRONOLACTONE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
198222	spironolactone 100 MG Oral Tablet	PSN	617aef1f-3f2c-4d33-8baf-40995b8f6a24	3
313096	spironolactone 25 MG Oral Tablet	PSN	617aef1f-3f2c-4d33-8baf-40995b8f6a24	3
198223	spironolactone 50 MG Oral Tablet	PSN	617aef1f-3f2c-4d33-8baf-40995b8f6a24	3
198222	spironolactone 100 MG Oral Tablet	SCD	617aef1f-3f2c-4d33-8baf-40995b8f6a24	3
313096	spironolactone 25 MG Oral Tablet	SCD	617aef1f-3f2c-4d33-8baf-40995b8f6a24	3
198223	spironolactone 50 MG Oral Tablet	SCD	617aef1f-3f2c-4d33-8baf-40995b8f6a24	3

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
SPIRONOLACTONE TABLETS, USP	Actavis Pharma, Inc.	2015-03-31	HUMAN PRESCRIPTION DRUG LABEL	13
SPIRONOLACTONE TABLETS, USP	Physicians Total Care, Inc.	2011-12-29	HUMAN PRESCRIPTION DRUG LABEL	3