Mederma PM

Product NDC: 0259-2202
11-digit product format: 002592202
Labeler code: 0259
Product ID: 0259-2202_2988a54d-5ee7-47bd-a00a-6e43993c5894
Type: HUMAN OTC DRUG
Nonproprietary name: Dimethicone
Dosage form: CREAM
Route: TOPICAL
Labeler: Merz Pharmaceuticals, LLC
Application: part347
Marketing category: OTC MONOGRAPH FINAL
Marketing start: 2013-11-01
Marketing end: 2024-07-31
Substance: DIMETHICONE
Active strength: 20 mg/g
Pharmacologic classes: Skin Barrier Activity [PE]
NDC exclude flag: No
Listing certified through: 0000-00-00
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	0259-2202		D	Discontinued by firm	2026-08-11
excluded package	package	0259-2202	0259-2202-28	D	Discontinued by firm	2026-08-11
excluded package	package	0259-2202	0259-2202-48	D	Discontinued by firm	2026-08-11

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 34 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0259-2202-28	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0259-2202-48	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0259-2202-28	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0259-2202-48	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0259-2202-28	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0259-2202-48	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0259-2202-28	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0259-2202-48	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0259-2202-28	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0259-2202-48	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0259-2202-28	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0259-2202-48	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0259-2202-28	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0259-2202-48	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0259-2202-28	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0259-2202-48	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0259-2202-28	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0259-2202-48	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0259-2202-28	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0259-2202-48	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0259-2202-28	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0259-2202-48	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0259-2202-48	`557ba5c1ecfa…`	`9c80585c8c6e…`

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Related label table
NDC	Effective	Related label
0259-2202-28	2022-02-25	Mederma ® PM
0259-2202-48	2022-02-25	Mederma ® PM
0259-2202-28	2022-01-28	Mederma ® PM
0259-2202-48	2022-01-28	Mederma ® PM
0259-2202-28	2020-02-07	Mederma ® PM
0259-2202-48	2020-02-07	Mederma ® PM
0259-2202-28	2020-01-31	Mederma ® PM
0259-2202-48	2020-01-31	Mederma ® PM

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0259-2202-28	GM - Gram	0259-2202	637e1135-930e-4ac1-a350-4589f6c1ea95	1	2022-06-06
0259-2202-48	GM - Gram	0259-2202	71ebd141-d817-4da9-9b11-6fa225502da1	1	2022-06-06

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Dimethicone	ACTIVE INGREDIENT	92RU3N3Y1O	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Dimethicone	ACTIVE MOIETY	92RU3N3Y1O	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
.Alpha.-Tocopherol Acetate	INACTIVE INGREDIENT	9E8X80D2L0	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Alanine	INACTIVE INGREDIENT	OF5P57N2ZX	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Alcohol	INACTIVE INGREDIENT	3K9958V90M	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Alkyl (C12-15) Benzoate	INACTIVE INGREDIENT	A9EJ3J61HQ	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Aloe Vera Leaf	INACTIVE INGREDIENT	ZY81Z83H0X	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Arachidyl alcohol	INACTIVE INGREDIENT	1QR1QRA9BU	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Arachidyl glucoside	INACTIVE INGREDIENT	6JVW35JOOJ	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Arginine Hydrochloride	INACTIVE INGREDIENT	F7LTH1E20Y	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Aspartic Acid	INACTIVE INGREDIENT	30KYC7MIAI	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Bovine Type I Collagen	INACTIVE INGREDIENT	FHJ3ATL51C	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Cetearyl Glucoside	INACTIVE INGREDIENT	09FUA47KNA	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Cetostearyl Alcohol	INACTIVE INGREDIENT	2DMT128M1S	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Citric Acid Monohydrate	INACTIVE INGREDIENT	2968PHW8QP	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Cyclomethicone	INACTIVE INGREDIENT	NMQ347994Z	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Dextrose	INACTIVE INGREDIENT	IY9XDZ35W2	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Dicaprylyl Carbonate	INACTIVE INGREDIENT	609A3V1SUA	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Docosanol	INACTIVE INGREDIENT	9G1OE216XY	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Glutamic Acid	INACTIVE INGREDIENT	3KX376GY7L	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Glycerin	INACTIVE INGREDIENT	PDC6A3C0OX	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Glycine	INACTIVE INGREDIENT	TE7660XO1C	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Histidine Monohydrochloride	INACTIVE INGREDIENT	1D5Q932XM6	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Hydroxyethyl acrylate/Sodium acryloyldimethyl Taurate Copolymer (45000 MPA.S AT 1%)	INACTIVE INGREDIENT	86FQE96TZ4	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Hydroxyethyl Cellulose (2000 MPA.S AT 1%)	INACTIVE INGREDIENT	S38J6RZN16	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Isoleucine	INACTIVE INGREDIENT	04Y7590D77	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Isopropyl Alcohol	INACTIVE INGREDIENT	ND2M416302	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Leucine	INACTIVE INGREDIENT	GMW67QNF9C	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Lysine Hydrochloride	INACTIVE INGREDIENT	JNJ23Q2COM	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Mannitol	INACTIVE INGREDIENT	3OWL53L36A	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Onion	INACTIVE INGREDIENT	492225Q21H	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Panthenol	INACTIVE INGREDIENT	WV9CM0O67Z	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Pentylene Glycol	INACTIVE INGREDIENT	50C1307PZG	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Phenylalanine	INACTIVE INGREDIENT	47E5O17Y3R	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
POLYETHYLENE GLYCOL 400	INACTIVE INGREDIENT	B697894SGQ	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Potassium Sorbate	INACTIVE INGREDIENT	1VPU26JZZ4	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Prezatide Copper	INACTIVE INGREDIENT	6BJQ43T1I9	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Sodium Benzoate	INACTIVE INGREDIENT	OJ245FE5EU	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Sodium Hydroxide	INACTIVE INGREDIENT	55X04QC32I	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Sodium Lactate	INACTIVE INGREDIENT	TU7HW0W0QT	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Sorbitol	INACTIVE INGREDIENT	506T60A25R	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Soy Protein	INACTIVE INGREDIENT	R44IWB3RN5	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Tromethamine	INACTIVE INGREDIENT	023C2WHX2V	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Tyrosine	INACTIVE INGREDIENT	42HK56048U	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
Valine	INACTIVE INGREDIENT	HG18B9YRS7	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2
water	INACTIVE INGREDIENT	059QF0KO0R	MEDERMA PM (DIMETHICONE) CREAM [MERZ PHARMACEUTICALS, LLC]	2

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
92RU3N3Y1O	DIMETHICONE	9006-65-9	DIMETHICONE

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0259-2202-28	00259220228	1 TUBE in 1 BOX (0259-2202-28) > 28 g in 1 TUBE	1 tube	2013-11-01	2024-07-31	No	No	Current
0259-2202-48	00259220248	1 JAR in 1 BOX (0259-2202-48) > 48 g in 1 JAR	1 jar	2013-11-01	2023-04-30	No	No	Current