Aleve liquid gels

Product NDC
0280-0105
11-digit product format
002800105
Labeler code
0280
Product ID
0280-0105_2766b060-5c1b-41fb-b8ca-cfb1a021b64e
Type
HUMAN OTC DRUG
Nonproprietary name
Naproxen Sodium
Dosage form
CAPSULE, LIQUID FILLED
Route
ORAL
Labeler
Bayer Healthcare LLC
Application
ANDA214463
Marketing category
ANDA
Marketing start
2023-12-01
Substance
NAPROXEN SODIUM
Active strength
220 mg/1
Pharmacologic classes
Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Nonsteroidal Anti-inflammatory Drug [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A214463-001NAPROXEN SODIUMNAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-1031067a03dcf5…
2025-08-23 18:47 UTC2025-08A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-106a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-1003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-102680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-105bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-1079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-101e350fbaab3a…
2024-05-31 18:47 UTC2024-05A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-108072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-106a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-101c564ffb4f44…
2023-12-20 04:57 UTC2023-12A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-109b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-103f0d92c62455…
2023-05-13 08:27 UTC2023-05A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10053a50430f4f…
2023-01-26 05:58 UTC2023-01A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-103bdfa0b2c4d7…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A214463-001NAPROXEN SODIUMEQ 200MG BASECAPSULE / ORAL2023-01-10a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Aleve liquid gels
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
NAPROXEN SODIUM220 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
9TN87S3A3CInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1112231Internal RxNorm lookup
1112233Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
a0587c73-d297-462d-a0ef-750cb324486eAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
fef6ad89-235f-4274-ba49-a8e53642473eProduct name220250225
87fed3e6-8fba-48ef-96b0-3a7fb54b96ffProduct name320230306
b5fdaaec-7251-4da6-9cb2-4e9e76939ec8Product name120200623
e76dbbc1-775d-722c-08ff-ed45e8a80defProduct name320181002
6f4f4521-fd56-1ae6-888b-3b021bd75c7cProduct name120140508
ce67e27d-1d21-5465-4409-b0662dd99d4dProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0280-0105-01Aleve liquid gels120 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED1202
0280-0105-02Aleve liquid gels160 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED1602
0280-0105-03Aleve liquid gels20 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED202
0280-0105-04Aleve liquid gels50 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED502
0280-0105-05Aleve liquid gels80 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED802
0280-0105-06Aleve liquid gels80 in 1 BOTTLE, PLASTICCAPSULE, LIQUID FILLED802

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0280-0105ALEVE LIQUID GELS (NAPROXEN SODIUM) CAPSULE, LIQUID FILLED [BAYER HEALTHCARE LLC]2Current NDC, 6 package rows20240510_a0587c73-d297-462d-a0ef-750cb324486e.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Aleve liquid gelsNAPROXEN SODIUMBayer Healthcare LLCa0587c73-d297-462d-a0ef-750cb324486e2024-05-06WarningsExact identifier
application applno (ANDA): 214463
application number: ANDA214463
ndc (product): 0280-0105

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1112233Aleve 220 MG Oral CapsulePSNa0587c73-d297-462d-a0ef-750cb324486e2
1112231naproxen sodium 220 MG Oral CapsulePSNa0587c73-d297-462d-a0ef-750cb324486e2
1112233naproxen sodium 220 MG Oral Capsule [Aleve]SBDa0587c73-d297-462d-a0ef-750cb324486e2
1112231naproxen sodium 220 MG Oral CapsuleSCDa0587c73-d297-462d-a0ef-750cb324486e2
1112233Aleve 220 MG (naproxen 200 MG) Oral CapsuleSYa0587c73-d297-462d-a0ef-750cb324486e2
1112233Aleve 220 MG Oral CapsuleSYa0587c73-d297-462d-a0ef-750cb324486e2
1112231naproxen sodium 220 MG (as naproxen 200 MG) Oral CapsuleSYa0587c73-d297-462d-a0ef-750cb324486e2

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
0280-0105-0100280010501120 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-01) 2024-06-28NoNoCurrent
0280-0105-0200280010502160 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-02) 2023-12-01NoNoCurrent
0280-0105-030028001050320 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-03) 2024-05-07NoNoCurrent
0280-0105-040028001050450 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-04) 2024-05-14NoNoCurrent
0280-0105-050028001050580 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-05) 2024-05-21NoNoCurrent
0280-0105-060028001050680 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0280-0105-06) 2024-06-17NoNoCurrent