Alka-Seltzer Heartburn ReliefChews

Product NDC: 0280-0221
Requested package NDC: 0280-0221-01
11-digit product format: 002800221
Labeler code: 0280
Product ID: 0280-0221_45265f2e-3069-19ad-e063-6294a90ad41f
Type: HUMAN OTC DRUG
Nonproprietary name: CALCIUM CARBONATE
Dosage form: TABLET, CHEWABLE
Route: ORAL
Labeler: Bayer HealthCare LLC.
Application: M001
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2014-03-15
Substance: CALCIUM CARBONATE
Active strength: 750 mg/1
Pharmacologic classes: Blood Coagulation Factor [EPC], Calcium [CS], Cations, Divalent [CS], Increased Coagulation Factor Activity [PE], Phosphate Binder [EPC], Phosphate Chelating Activity [MoA]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Alka-Seltzer Heartburn ReliefChews
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
CALCIUM CARBONATE	750 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
H0G9379FGK	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
308915	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
bdb43d3b-ddcd-4359-a174-a5556e7c5f57	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
bee4fa8d-8d82-423a-a0b5-40a89dd13a99	Product name	1	20250618
e0d2eb29-08bd-4bba-90d1-c91c68a38767	Product name	4	20250516
30b0ac6e-02aa-0e5c-0d8b-cffdf3a282b2	Product name	5	20250304
334fe8d2-68fb-4331-a576-420e302ec069	Product name	7	20240320
444b3e50-f226-46ef-bfca-2e7035d140cd	Product name	1	20190611
e92765c1-be81-432a-b909-1b10777ec378	Product name	1	20190208
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
d5e51f11-ad28-caa4-4b49-4143974782ad	Product name	1	20150831
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324
0441a8f5-3835-497c-aedd-bc78cba56b2a	Product name	1	20150317
87711080-88eb-65c5-b2dd-bf99e700a372	Product name	1	20140508
ec2149b3-5c6d-5344-f757-c86411073075	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0280-0221-01	Alka-Seltzer Heartburn ReliefChews	32 in 1 BOTTLE, PLASTIC	TABLET, CHEWABLE	32	9
0280-0221-02	Alka-Seltzer Heartburn ReliefChews	66 in 1 BOTTLE, PLASTIC	TABLET, CHEWABLE	66	9
0280-0221-03	Alka-Seltzer Heartburn ReliefChews	200 in 1 BOTTLE, PLASTIC	TABLET, CHEWABLE	200	9
0280-0221-08	Alka-Seltzer Heartburn ReliefChews	8 in 1 POUCH	TABLET, CHEWABLE	8	9
0280-0221-12	Alka-Seltzer Heartburn ReliefChews	120 in 1 BOTTLE, PLASTIC	TABLET, CHEWABLE	120	9
0280-0221-36	Alka-Seltzer Heartburn ReliefChews	36 in 1 BOTTLE, PLASTIC	TABLET, CHEWABLE	36	9
0280-0221-60	Alka-Seltzer Heartburn ReliefChews	60 in 1 BOTTLE, PLASTIC	TABLET, CHEWABLE	60	9
0280-0221-90	Alka-Seltzer Heartburn ReliefChews	90 in 1 BOTTLE, PLASTIC	TABLET, CHEWABLE	90	9

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0280-0221-36	EA - Each	0280-0221	4a6ba300-7bd1-4e84-b4df-00de7ead1ec3	1	2019-09-05
0280-0221-60	EA - Each	0280-0221	a8632e0a-8cae-486d-b2e7-8ef50d7f6101	1	2019-09-05

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
CALCIUM CARBONATE	ACTIVE INGREDIENT	H0G9379FGK	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
CALCIUM CATION	ACTIVE MOIETY	2M83C4R6ZB	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
.ALPHA.-TOCOPHEROL, DL-	INACTIVE INGREDIENT	7QWA1RIO01	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
ACACIA	INACTIVE INGREDIENT	5C5403N26O	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
ALUMINUM OXIDE	INACTIVE INGREDIENT	LMI26O6933	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
CARNAUBA WAX	INACTIVE INGREDIENT	R12CBM0EIZ	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
CITRIC ACID MONOHYDRATE	INACTIVE INGREDIENT	2968PHW8QP	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
CORN SYRUP	INACTIVE INGREDIENT	9G5L16BK6N	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
FD&C BLUE NO. 1	INACTIVE INGREDIENT	H3R47K3TBD	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
FD&C RED NO. 40	INACTIVE INGREDIENT	WZB9127XOA	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
FD&C YELLOW NO. 5	INACTIVE INGREDIENT	I753WB2F1M	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
FD&C YELLOW NO. 6	INACTIVE INGREDIENT	H77VEI93A8	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
HYDROGENATED COCONUT OIL	INACTIVE INGREDIENT	JY81OXM1OM	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
LECITHIN, SOYBEAN	INACTIVE INGREDIENT	1DI56QDM62	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
MEDIUM-CHAIN TRIGLYCERIDES	INACTIVE INGREDIENT	C9H2L21V7U	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
METHYLPARABEN	INACTIVE INGREDIENT	A2I8C7HI9T	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
PHOSPHORIC ACID	INACTIVE INGREDIENT	E4GA8884NN	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
PROPYLPARABEN	INACTIVE INGREDIENT	Z8IX2SC1OH	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SHELLAC	INACTIVE INGREDIENT	46N107B71O	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SODIUM BENZOATE	INACTIVE INGREDIENT	OJ245FE5EU	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SORBIC ACID	INACTIVE INGREDIENT	X045WJ989B	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SORBITOL	INACTIVE INGREDIENT	506T60A25R	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SUCROSE	INACTIVE INGREDIENT	C151H8M554	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
TITANIUM DIOXIDE	INACTIVE INGREDIENT	15FIX9V2JP	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
YELLOW WAX	INACTIVE INGREDIENT	2ZA36H0S2V	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0280-0221	ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE LLC.]	8	Current NDC, Legacy NDC, 8 package rows	20241208_bdb43d3b-ddcd-4359-a174-a5556e7c5f57.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 14 of 34 · 678 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Equate Ultra Stregth Antacid	CALCIUM CARBONATE	Wal-Mart Stores, Inc.	cdfe5c95-3f90-4620-a618-18bac0471c3e	2025-12-03	Warnings	Exact identifier application number: M001
Walgreens Fast Acting Heartburn Relief Extra Strength	ALUMINUM HYDROXIDE AND MAGNESIUM CARBONATE	WALGREEN CO.	6eae97f3-a174-4cbc-badc-777475d2f7af	2025-11-26	Warnings	Exact identifier application number: M001
Antacid Regular Strength	ANTACID	WALGREEN CO.	ce5eef7f-497d-4c88-be6a-17eeb6e07f5b	2025-11-25	Warnings	Exact identifier application number: M001
Antacid Extra Strength	ANTACID	WALGREEN CO.	2981c5f7-121a-4030-86b1-559061030e7a	2025-11-25	Warnings	Exact identifier application number: M001
Antacid Extra Strength	ANTACID CALCIUM CARBONATE	WALGREEN CO.	14baa410-6ce3-4ddb-aac7-e2172d1506c4	2025-11-25	Warnings	Exact identifier application number: M001
Antacid Extra Strength	ANTACID	WALGREEN CO.	aa797e94-6560-41c9-8c71-458a1086e841	2025-11-25	Warnings	Exact identifier application number: M001
Extra Strength Antacid	CALCIUM CARBONATE	WALGREEN COMPANY	d66ec376-9cac-4de5-aac8-7c6f9aa210ce	2025-11-25	Warnings	Exact identifier application number: M001
Antacid Extra Strength Wintergreen	ANTACID	WALGREEN CO.	ae2cd8fb-73e2-43f4-8aa9-f92b06e21a6d	2025-11-25	Warnings	Exact identifier application number: M001
Antacid Ultra Strength	ANTACID	WALGREEN CO.	09ef90c3-1fc3-48be-8071-2fa387a46175	2025-11-25	Warnings	Exact identifier application number: M001
Antacid Ultra Strength Assorted Fruits	ANTACID	WALGREEN CO.	6d6cecdc-646b-4c7b-b325-9423c29c57fc	2025-11-25	Warnings	Exact identifier application number: M001
Antacid Ultra Strength Assorted Fruits	ANTACID	WALGREEN CO.	e1b55f3a-c6d7-4374-acc7-134786a3765e	2025-11-25	Warnings	Exact identifier application number: M001
ULTRA STRENGTH Antacid	CALCIUM CARBONATE	WALGREEN CO	a4dcf7b9-d2c3-45d3-9410-fc4d55052a3c	2025-11-25	Warnings	Exact identifier application number: M001
FAST ACTING Heartburn Relief	ALUMINUM HYDROXIDE AND MAGNESIUM CARBONATE	WALGREEN CO.	48c14005-811a-4868-b33e-934845504856	2025-11-25	Warnings	Exact identifier application number: M001
Walgreens Childrens Saline Laxative	MAGNESIUM HYDROXIDE	WALGREEN CO.	3813ed22-cf68-4c16-9b61-c39828120079	2025-11-25	Warnings	Exact identifier application number: M001
Ultra Strength Assorted Berries	CALCIUM CARBONATE	SAM'S WEST INC	bc619258-7451-460c-9472-95678ea82d6e	2025-11-20	Warnings	Exact identifier application number: M001
Gelusil	ALUMINA, MAGNESIA, SIMETHICONE	WellSpring Pharmaceutical Corporation	92fbeec1-1562-40f3-9734-41f133d494f9	2025-11-20	Warnings	Exact identifier application number: M001
GERI-MOX ANTACID ANTIGAS	ALUMINUM HYDROXIDE, MAGNESIUM HYDROXIDE, DIMETHICONE	Geri-Care Pharmaceuticals, Corp	03358bc7-8819-4a05-bc13-27fbf486bd26	2025-11-20	Warnings	Exact identifier application number: M001
Melox	ALUMINUM HYDROXIDE, MAGNESIUM HYDROXIDE, SIMETHICONE	Belmora LLC	d41f0b26-5add-4045-9754-37d70d120d28	2025-11-20	Warnings	Exact identifier application number: M001
Tums Chewy Bites Vanilla and Mint	CALCIUM CARBONATE	Haleon US Holdings LLC	2b9dd909-c850-3c21-e063-6394a90a15a8	2025-11-19	Warnings	Exact identifier application number: M001
MAXIMUM STRENGTH ANTACID ANTIGAS	ALUMINUM HYDROXIDE, MAGNESIUM HYDROXIDE, SIMETHICONE	WALGREEN COMPANY	7cd8fdf4-f762-f936-e053-2a91aa0aa6ee	2025-11-19	Warnings	Exact identifier application number: M001

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
H0G9379FGK	CALCIUM CARBONATE	471-34-1	CALCIUM CARBONATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
308915	calcium carbonate 750 MG (Ca 300 MG) Chewable Tablet	PSN	bdb43d3b-ddcd-4359-a174-a5556e7c5f57	9
308915	calcium carbonate 750 MG Chewable Tablet	SCD	bdb43d3b-ddcd-4359-a174-a5556e7c5f57	9
308915	calcium carbonate 750 MG (calcium 300 MG) Chewable Tablet	SY	bdb43d3b-ddcd-4359-a174-a5556e7c5f57	9

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0280-0221-01	00280022101	32 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0221-01)	2020-03-01	0000-00-00	No	No	Current