Home NDC 0280-0221 Alka-Seltzer Heartburn ReliefChews
Product NDC 0280-0221
11-digit product format 002800221
Labeler code 0280
Product ID 0280-0221_45265f2e-3069-19ad-e063-6294a90ad41f
Type HUMAN OTC DRUG
Nonproprietary name CALCIUM CARBONATE
Dosage form TABLET, CHEWABLE
Route ORAL
Labeler Bayer HealthCare LLC.
Application M001
Marketing category OTC MONOGRAPH DRUG
Marketing start 2014-03-15
Substance CALCIUM CARBONATE
Active strength 750 mg/1
Pharmacologic classes Blood Coagulation Factor [EPC], Calcium [CS], Cations, Divalent [CS], Increased Coagulation Factor Activity [PE], Phosphate Binder [EPC], Phosphate Chelating Activity [MoA]
NDC exclude flag No
Listing certified through 2026-12-31
Current FDA listing Yes Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Alka-Seltzer Heartburn ReliefChews
Listing expiration 2026-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength CALCIUM CARBONATE 750 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination H0G9379FGK Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 308915 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 0280-0221-01 Alka-Seltzer Heartburn ReliefChews 32 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 32 9 0280-0221-02 Alka-Seltzer Heartburn ReliefChews 66 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 66 9 0280-0221-03 Alka-Seltzer Heartburn ReliefChews 200 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 200 9 0280-0221-08 Alka-Seltzer Heartburn ReliefChews 8 in 1 POUCH TABLET, CHEWABLE 8 9 0280-0221-12 Alka-Seltzer Heartburn ReliefChews 120 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 120 9 0280-0221-36 Alka-Seltzer Heartburn ReliefChews 36 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 36 9 0280-0221-60 Alka-Seltzer Heartburn ReliefChews 60 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 60 9 0280-0221-90 Alka-Seltzer Heartburn ReliefChews 90 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 90 9
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded CALCIUM CARBONATE ACTIVE INGREDIENT H0G9379FGK ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 CALCIUM CATION ACTIVE MOIETY 2M83C4R6ZB ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 .ALPHA.-TOCOPHEROL, DL- INACTIVE INGREDIENT 7QWA1RIO01 ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 ACACIA INACTIVE INGREDIENT 5C5403N26O ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 ALUMINUM OXIDE INACTIVE INGREDIENT LMI26O6933 ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 CARNAUBA WAX INACTIVE INGREDIENT R12CBM0EIZ ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 CITRIC ACID MONOHYDRATE INACTIVE INGREDIENT 2968PHW8QP ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 CORN SYRUP INACTIVE INGREDIENT 9G5L16BK6N ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 FD&C BLUE NO. 1 INACTIVE INGREDIENT H3R47K3TBD ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 FD&C RED NO. 40 INACTIVE INGREDIENT WZB9127XOA ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 FD&C YELLOW NO. 5 INACTIVE INGREDIENT I753WB2F1M ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 FD&C YELLOW NO. 6 INACTIVE INGREDIENT H77VEI93A8 ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 HYDROGENATED COCONUT OIL INACTIVE INGREDIENT JY81OXM1OM ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 LECITHIN, SOYBEAN INACTIVE INGREDIENT 1DI56QDM62 ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 MEDIUM-CHAIN TRIGLYCERIDES INACTIVE INGREDIENT C9H2L21V7U ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 METHYLPARABEN INACTIVE INGREDIENT A2I8C7HI9T ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 PHOSPHORIC ACID INACTIVE INGREDIENT E4GA8884NN ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 PROPYLENE GLYCOL INACTIVE INGREDIENT 6DC9Q167V3 ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 PROPYLPARABEN INACTIVE INGREDIENT Z8IX2SC1OH ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SHELLAC INACTIVE INGREDIENT 46N107B71O ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SODIUM BENZOATE INACTIVE INGREDIENT OJ245FE5EU ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SORBIC ACID INACTIVE INGREDIENT X045WJ989B ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SORBITOL INACTIVE INGREDIENT 506T60A25R ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 STARCH, CORN INACTIVE INGREDIENT O8232NY3SJ ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SUCROSE INACTIVE INGREDIENT C151H8M554 ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 TITANIUM DIOXIDE INACTIVE INGREDIENT 15FIX9V2JP ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 WATER INACTIVE INGREDIENT 059QF0KO0R ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 YELLOW WAX INACTIVE INGREDIENT 2ZA36H0S2V ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 0280-0221 ALKA-SELTZER HEARTBURN RELIEFCHEWS (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE LLC.] 8 Current NDC, Legacy NDC, 8 package rows 20241208_bdb43d3b-ddcd-4359-a174-a5556e7c5f57.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 23 of 34 · 678 matching rows.
Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join Extra Strength Antacid CALCIUM CARBONATE Discount Drug Mart, Inc 2e0d5be6-d41b-cdf8-e063-6394a90a08b4 2025-02-27 Warnings Exact identifier application number: M001 Supreme Antacid Cherry CALCIUM CARBONATE, MAGNESIUM HYDROXIDE Discount Drug Mart, Inc 2e0a1913-c3d4-7c7d-e063-6294a90a4841 2025-02-26 Warnings Exact identifier application number: M001 Extra Strength sugar free Antacid CALCIUM CARBONATE Discount Drug Mart, Inc 2e09f87b-c771-59ae-e063-6294a90a0c39 2025-02-25 Warnings Exact identifier application number: M001 Ultra Strength Antacid Wintergreen Flavor CALCIUM CARBONATE Xiamen Kang Zhongyuan Biotechnology Co., Ltd. 409b5d06-3398-4414-8919-10b9064ba4ee 2025-02-25 Warnings Exact identifier application number: M001 Extra Strength Antacid Tropical Fruit CALCIUM CARBONATE Discount Drug Mart, Inc 2df92d5c-cd5a-060b-e063-6394a90aa51f 2025-02-25 Warnings Exact identifier application number: M001 Ultra Strength Antacid Assorted Fruit CALCIUM CARBONATE Discount Drug Mart, Inc 2e09cb3b-cf5d-15b1-e063-6394a90a5c6a 2025-02-25 Warnings Exact identifier application number: M001 Extra Strength Smooth Assorted Fruit Antacid CALCIUM CARBONATE Discount Drug Mart, Inc 2df86c35-1e9b-eb49-e063-6294a90aabb6 2025-02-20 Warnings Exact identifier application number: M001 Regular Strength Antacid Regular strength Antacid CALCIUM CARBONATE Discount Drug Mart, Inc 2dfa0de5-6e58-dc9d-e063-6294a90a53e0 2025-02-20 Warnings Exact identifier application number: M001 Childrens Tummy Relief CALCIUM CARBONATE Genexa Inc. f4d39d3e-82d0-2673-e053-2995a90a7d2a 2025-02-20 Warnings Exact identifier application number: M001 Extra Strength Smooth Peppermint Antacid CALCIUM CARBONATE Discount Drug Mart, Inc 2df8fe2b-cc9a-f026-e063-6394a90aa0ad 2025-02-20 Warnings Exact identifier application number: M001 Extra Strength Antacid CALCIUM CARBONATE Harris Teeter, LLC 2cb4ce4e-e18c-c96d-e063-6394a90a18ca 2025-02-20 Warnings Exact identifier application number: M001 Extra Strength Smooth Antacid CALCIUM CARBONATE Harris Teeter, LLC 2cb60b7e-711a-8052-e063-6394a90acf1d 2025-02-20 Warnings Exact identifier application number: M001 Extra Strength Antacid CALCIUM CARBONATE Discount Drug Mart, Inc 2df9e47a-8741-6958-e063-6394a90a6c60 2025-02-20 Warnings Exact identifier application number: M001 Regular Strength Antacid Peppermint CALCIUM CARBONATE Discount Drug Mart, Inc 2e09b8d1-25b4-0e57-e063-6394a90a31e2 2025-02-20 Warnings Exact identifier application number: M001 Tums Chewy Bites Orange and Cream ES CALCIUM CARBONATE Haleon US Holdings LLC 036ef1ed-32ef-46b8-8817-b3f63a014280 2025-02-14 Warnings Exact identifier application number: M001 Tums Naturals CALCIUM CARBONATE Haleon US Holdings LLC d8da54b8-6456-4e7d-acd2-a55e2249bd01 2025-02-13 Warnings Exact identifier application number: M001 Ultra Strength Antacid Assorted Fruit CALCIUM CARBONATE Harris Teeter, LLC 2cb4c58f-ee88-b60e-e063-6294a90a1e6c 2025-02-12 Warnings Exact identifier application number: M001 Maximum Strength Antacid Cherry ALUMINUM HYDROXIDE, MAGNESIUM HYDROXIDE, SIMETHICONE Harris Teeter, LLC 2c4fc835-a9ad-2666-e063-6394a90a20ac 2025-02-12 Warnings Exact identifier application number: M001 Maximum Strength Antacid ALUMINUM HYDROXIDE, MAGNESIUM HYDROXIDE, SIMETHICONE Harris Teeter, LLC 2c5081a6-367f-28bc-e063-6294a90a459e 2025-02-12 Warnings Exact identifier application number: M001 Regular Strength Antacid Peppermint CALCIUM CARBONATE Harris Teeter, LLC 2cb54a40-98ce-2660-e063-6294a90a3ed0 2025-02-11 Warnings Exact identifier application number: M001
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Marketing start Marketing end Sample Exclude flag Status 0280-0221-01 00280022101 32 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0221-01) 2020-03-01 0000-00-00 No No Current 0280-0221-02 00280022102 66 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0221-02) 2020-03-01 0000-00-00 No No Current 0280-0221-03 00280022103 200 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0221-03) 2023-08-15 No No Current 0280-0221-08 00280022108 8 TABLET, CHEWABLE in 1 POUCH (0280-0221-08) 2016-03-23 0000-00-00 No No Current 0280-0221-12 00280022112 120 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0221-12) 2014-03-15 0000-00-00 No No Current 0280-0221-36 00280022136 36 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0221-36) 2014-03-15 0000-00-00 No No Current 0280-0221-60 00280022160 60 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0221-60) 2014-03-15 0000-00-00 No No Current 0280-0221-90 00280022190 90 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0221-90) 2015-08-12 0000-00-00 No No Current