Alka-Seltzer Heartburn ReliefChews Strawberry and Orange

Product NDC: 0280-0224
11-digit product format: 002800224
Labeler code: 0280
Product ID: 0280-0224_45265f01-4741-fd1f-e063-6294a90ad28f
Type: HUMAN OTC DRUG
Nonproprietary name: CALCIUM CARBONATE
Dosage form: TABLET, CHEWABLE
Route: ORAL
Labeler: Bayer HealthCare LLC.
Application: M001
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2014-03-15
Substance: CALCIUM CARBONATE
Active strength: 750 mg/1
Pharmacologic classes: Blood Coagulation Factor [EPC], Calcium [CS], Cations, Divalent [CS], Increased Coagulation Factor Activity [PE], Phosphate Binder [EPC], Phosphate Chelating Activity [MoA]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Alka-Seltzer Heartburn ReliefChews Strawberry and Orange
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
CALCIUM CARBONATE	750 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
H0G9379FGK	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
308915	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
8745ae49-e6d6-43d6-9530-bcdf0b6c90e5	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
bee4fa8d-8d82-423a-a0b5-40a89dd13a99	Product name	1	20250618
e0d2eb29-08bd-4bba-90d1-c91c68a38767	Product name	4	20250516
30b0ac6e-02aa-0e5c-0d8b-cffdf3a282b2	Product name	5	20250304
334fe8d2-68fb-4331-a576-420e302ec069	Product name	7	20240320
444b3e50-f226-46ef-bfca-2e7035d140cd	Product name	1	20190611
e92765c1-be81-432a-b909-1b10777ec378	Product name	1	20190208
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
d5e51f11-ad28-caa4-4b49-4143974782ad	Product name	1	20150831
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324
0441a8f5-3835-497c-aedd-bc78cba56b2a	Product name	1	20150317
87711080-88eb-65c5-b2dd-bf99e700a372	Product name	1	20140508
ec2149b3-5c6d-5344-f757-c86411073075	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
0280-0224-06	Alka-Seltzer Heartburn ReliefChews Strawberry and Orange	6 in 1 BLISTER PACK	TABLET, CHEWABLE	6		8
0280-0224-06	Alka-Seltzer Heartburn ReliefChews Strawberry and Orange	1 in 1 CARTON	TABLET, CHEWABLE	1		8

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0280-0224-06	EA - Each	0280-0224	98e7ccd4-d1f8-4cc5-b1d2-0cb5449813c9	1	2018-03-08

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
CALCIUM CARBONATE	ACTIVE INGREDIENT	H0G9379FGK	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
CALCIUM CATION	ACTIVE MOIETY	2M83C4R6ZB	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
ACACIA	INACTIVE INGREDIENT	5C5403N26O	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
ALUMINUM OXIDE	INACTIVE INGREDIENT	LMI26O6933	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
CARNAUBA WAX	INACTIVE INGREDIENT	R12CBM0EIZ	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
CITRIC ACID MONOHYDRATE	INACTIVE INGREDIENT	2968PHW8QP	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
CORN SYRUP	INACTIVE INGREDIENT	9G5L16BK6N	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
FD&C BLUE NO. 1	INACTIVE INGREDIENT	H3R47K3TBD	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
FD&C RED NO. 40	INACTIVE INGREDIENT	WZB9127XOA	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
FD&C YELLOW NO. 6	INACTIVE INGREDIENT	H77VEI93A8	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
HYDROGENATED COCONUT OIL	INACTIVE INGREDIENT	JY81OXM1OM	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
MEDIUM-CHAIN TRIGLYCERIDES	INACTIVE INGREDIENT	C9H2L21V7U	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
METHYLPARABEN	INACTIVE INGREDIENT	A2I8C7HI9T	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
PHOSPHORIC ACID	INACTIVE INGREDIENT	E4GA8884NN	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SHELLAC	INACTIVE INGREDIENT	46N107B71O	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SODIUM BENZOATE	INACTIVE INGREDIENT	OJ245FE5EU	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SORBIC ACID	INACTIVE INGREDIENT	X045WJ989B	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SORBITOL	INACTIVE INGREDIENT	506T60A25R	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
SUCROSE	INACTIVE INGREDIENT	C151H8M554	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
TITANIUM DIOXIDE	INACTIVE INGREDIENT	15FIX9V2JP	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1
WHITE WAX	INACTIVE INGREDIENT	7G1J5DA97F	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0280-0224	ALKA-SELTZER HEARTBURN RELIEFCHEWS STRAWBERRY AND ORANGE (CALCIUM CARBONATE) TABLET, CHEWABLE [BAYER HEALTHCARE LLC.]	7	Current NDC, Legacy NDC, 2 package rows	20241208_8745ae49-e6d6-43d6-9530-bcdf0b6c90e5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 28 of 34 · 678 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
TopCare Extra Strength Antacid Extra Strength Antacid Assorted Berry	CALCIUM CARBONATE	Topco Associates, LLC	0aefbd70-4103-410c-83b2-f7baa0b80ddd	2024-12-09	Warnings	Exact identifier application number: M001
Topcare Extra Strength Antacid Assorted Fruit Extra Strength Antacid Assorted Fruit	CALCIUM CARBONATE	Topco Associates, LLC	563a9951-0d40-448b-bf0d-8f6d905087d0	2024-12-09	Warnings	Exact identifier application number: M001
REGULAR STRENGTH ANTACID MINT	ALUMINUM HYDROXIDE, MAGNESIUM HYDROXIDE, DIMETHICONE	CVS	3cdfa932-6a20-2a82-e054-00144ff88e88	2024-12-05	Warnings	Exact identifier application number: M001
TUMS EX	CALCIUM CARBONATE	Haleon US Holdings LLC	593a0494-d669-4bcf-8412-b92645b2d76c	2024-12-05	Warnings	Exact identifier application number: M001
First Aid Only Antacid	CALCIUM CARBONATE	Acme United Corporation	68902dda-a13c-ff2e-e053-2991aa0a06b1	2024-11-26	Warnings	Exact identifier application number: M001
Antacid Peppermint Flavour Regular Strength	CALCIUM CARBONATE	American Health Packaging	782398a8-a3d9-4766-a7e1-ceb6d65152b2	2024-11-21	Warnings	Exact identifier application number: M001
Tums Antacid Chewy Bites	CALCIUM CARBONATE 750 MG	Lil' Drug Store products, Inc.	0803ad9c-1da8-a556-e063-6294a90add7f	2024-11-20	Warnings	Exact identifier application number: M001
CHOOZ	CALCIUM CARBONATE	Leosons Overseas Corp.	9faf82d9-ed83-4007-b580-117d7e7fefc7	2024-11-18	Warnings	Exact identifier application number: M001
Sal de Uvas Picot	CITRIC ACID MONOHYDRATE AND SODIUM BICARBONATE	RB Health Mexico, S.A. de C.V.	151b9bc9-1a6e-4401-ae58-4b4210ab4505	2024-11-15	Warnings	Exact identifier application number: M001
Calcium Carbonate	CALCIUM CARBONATE	PAI Holdings, LLC dba PAI Pharma	d89f3184-7081-4e16-a504-9214283891f6	2024-11-12	Warnings	Exact identifier application number: M001
Rite Aid Extra Strength	ALUMINUM HYDROXIDE AND MAGNESIUM CARBONATE	RITE AID CORPORATION	d2f8dcc2-8833-4426-9c12-1a6087145122	2024-10-30	Warnings	Exact identifier application number: M001
RITE AID Pharmacy Ultra Strength Assorted Fruits	CALCIUM CARBONATE	RITE AID CORPORATION	2989649c-e5ab-4118-a4d4-0f22a7f9f0a0	2024-10-30	Warnings	Exact identifier application number: M001
Kids Antacid	CALCIUM CARBONATE	RITE AID CORPORATION	9255322d-dd0d-4429-b1ca-805c7348c38d	2024-10-30	Warnings	Exact identifier application number: M001
Extra Strength Smooth Antacid	CALCIUM CARBONATE	RITE AID CORPORATION	23fa3378-d9f9-4671-ba1c-9c9611b1fbef	2024-10-30	Warnings	Exact identifier application number: M001
Rite Aid Extra Strength Assorted Fruit	CALCIUM CARBONATE	RITE AID CORPORATION	d405655a-260d-4a26-bf6f-053c6a6c87af	2024-10-30	Warnings	Exact identifier application number: M001
Extra Strength Antacid	CALCIUM CARBONATE	RITE AID CORPORATION	c6bbffbc-2d00-4a5c-80aa-5e59204cca9f	2024-10-30	Warnings	Exact identifier application number: M001
Rite Aid Extra Strength Assorted Fruits	CALCIUM CARBONATE	RITE AID CORPORATION	60d5fa96-528e-486c-ada2-cdfef090b61a	2024-10-30	Warnings	Exact identifier application number: M001
Rite Aid Ultra Strength Peppermint Flavor	CALCIUM CARBONATE	RITE AID CORPORATION	4e963099-fd7f-4862-9f9c-9f1fb963779e	2024-10-30	Warnings	Exact identifier application number: M001
Rite Aid Ultra Strength Assorted Berries	CALCIUM CARBONATE	RITE AID CORPORATION	ea918cb1-af3e-4a02-bd34-db4ad1b0e6bd	2024-10-30	Warnings	Exact identifier application number: M001
Rite Aid Extra Strength Tropical Fruit	CALCIUM CARBONATE	Rite Aid Corporation	ffb9d2bf-0818-4109-a6f9-2f0ac74b872c	2024-10-30	Warnings	Exact identifier application number: M001

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
H0G9379FGK	CALCIUM CARBONATE	471-34-1	CALCIUM CARBONATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
308915	calcium carbonate 750 MG (Ca 300 MG) Chewable Tablet	PSN	8745ae49-e6d6-43d6-9530-bcdf0b6c90e5	8
308915	calcium carbonate 750 MG Chewable Tablet	SCD	8745ae49-e6d6-43d6-9530-bcdf0b6c90e5	8
308915	calcium carbonate 750 MG (calcium 300 MG) Chewable Tablet	SY	8745ae49-e6d6-43d6-9530-bcdf0b6c90e5	8

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0280-0224-06	00280022406	1 BLISTER PACK in 1 CARTON (0280-0224-06) / 6 TABLET, CHEWABLE in 1 BLISTER PACK	1 blister pack	2014-03-15	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Alka-Seltzer ® Heartburn ReliefChews™ Strawberry & Orange	Bayer HealthCare LLC.	2025-12-04	HUMAN OTC DRUG LABEL	8