Alka-Seltzer Plus Cold Medicine Sparkling Original

Product NDC: 0280-1400
11-digit product format: 002801400
Labeler code: 0280
Product ID: 0280-1400_4526711d-1058-262c-e063-6294a90aef61
Type: HUMAN OTC DRUG
Nonproprietary name: ASPIRIN, CHLORPHENIRAMINE MALEATE, and PHENYLEPHRINE BITARTRATE
Dosage form: TABLET, EFFERVESCENT
Route: ORAL
Labeler: Bayer HealthCare LLC.
Application: M013
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2008-04-10
Substance: ASPIRIN; CHLORPHENIRAMINE MALEATE; PHENYLEPHRINE BITARTRATE
Active strength: 325; 2; 7.8 mg/1; mg/1; mg/1
Pharmacologic classes: Adrenergic alpha1-Agonists [MoA], Anti-Inflammatory Agents, Non-Steroidal [CS], Cyclooxygenase Inhibitors [MoA], Decreased Platelet Aggregation [PE], Decreased Prostaglandin Production [PE], Histamine H1 Receptor Antagonists [MoA], Histamine-1 Receptor Antagonist [EPC], Nonsteroidal Anti-inflammatory Drug [EPC], Platelet Aggregation Inhibitor [EPC], alpha-1 Adrenergic Agonist [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 5 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded package	package	0280-1400	0280-1400-12	D	Discontinued by firm	2026-10-15
excluded package	package	0280-1400	0280-1400-20	D	Discontinued by firm	2026-10-15
excluded package	package	0280-1400	0280-1400-36	D	Discontinued by firm	2026-10-15
excluded package	package	0280-1400	0280-1400-48	D	Discontinued by firm	2026-10-15
excluded package	package	0280-1400	0280-1400-72	D	Discontinued by firm	2026-10-15

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 60 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	0280-1400-48	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	0280-1400-20	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	0280-1400-36	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	0280-1400-12	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	0280-1400-72	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	0280-1400-72	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	0280-1400-48	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	0280-1400-12	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	0280-1400-20	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	0280-1400-36	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	0280-1400-72	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	0280-1400-48	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	0280-1400-12	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	0280-1400-20	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	0280-1400-36	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	0280-1400-72	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	0280-1400-48	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	0280-1400-12	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	0280-1400-20	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	0280-1400-36	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	0280-1400-72	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	0280-1400-48	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	0280-1400-12	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	0280-1400-20	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	0280-1400-36	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	0280-1400-72	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	0280-1400-48	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	0280-1400-12	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	0280-1400-20	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	0280-1400-36	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	0280-1400-72	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	0280-1400-48	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	0280-1400-12	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	0280-1400-20	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	0280-1400-36	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	0280-1400-72	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	0280-1400-48	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	0280-1400-12	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	0280-1400-20	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	0280-1400-36	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	0280-1400-72	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	0280-1400-48	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	0280-1400-12	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	0280-1400-20	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	0280-1400-36	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	0280-1400-72	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	0280-1400-48	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	0280-1400-12	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	0280-1400-20	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	0280-1400-36	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	0280-1400-72	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	0280-1400-48	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	0280-1400-12	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	0280-1400-20	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	0280-1400-36	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	0280-1400-72	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	0280-1400-48	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	0280-1400-12	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	0280-1400-20	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	0280-1400-36	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Alka-Seltzer Plus Cold Medicine Sparkling Original
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ASPIRIN	325 mg/1
CHLORPHENIRAMINE MALEATE	2 mg/1
PHENYLEPHRINE BITARTRATE	7.8 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
R16CO5Y76E	Internal UNII lookup
V1Q0O9OJ9Z	Internal UNII lookup
27O3Q5ML57	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1536840	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
78537dcf-b157-4b67-a8b2-5cb144815166	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
e4e263da-1c53-440f-bb80-b7a575843b5a	Product name	1	20260313
d2168cac-a261-415a-9c78-3522859fa720	Product name	3	20251124
05a8cdd1-eeb8-409e-b938-0778225eca7d	Product name	4	20250221
e5b5c132-b15d-435b-9faa-2f74e5cadcf9	Product name	8	20250220
fb7ab793-2c12-4079-b100-a64f73bef25a	Product name	4	20240712
f489e8f3-5c9e-4818-b539-a73587edcfc7	Product name	2	20240229
0f7ae452-206d-4fc4-868d-56fc47074084	Product name	1	20231011
b0cbf770-6cc3-4aa4-9158-755110c2b9f7	Product name	2	20230717
dc7c5daa-021f-40dd-b00d-63982cb2067a	Product name	1	20230426
d7724692-1155-4cc8-a415-22f5fc4aec35	Product name	6	20220216
bde672ba-4805-28d0-1986-73543d41b412	Product name	2	20210201
08ffbcbf-26df-b99c-1dab-64fc4cfae89f	Product name	5	20200925
b5abe2e3-39a1-43eb-9bff-f3c1653fe3df	Product name	2	20190930
816b97af-edc5-4060-aff1-b814bdbcad50	Product name	1	20190415
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
d17a97fa-387f-690e-d2be-0083ab044a03	Product name	3	20170725
0fdb98e2-b951-a1ce-5715-2b187ba500ef	Product name	4	20170718
419aab54-5d5a-4146-9453-026d4a9991be	Product name	2	20170525
f212291f-05fe-9603-fc7e-bd73e38ce1e6	Product name	2	20161129
ade821ba-260a-47e2-bd89-743e27ac9906	Product name	1	20161121
08ffbcbf-26df-b99c-1dab-64fc4cfae89f	Product name	2	20160823
182f9ab4-4ab5-c449-200f-87ce2ce8e550	Product name	2	20151105
9425d234-4ae1-4b53-adc6-8cc7af6dd657	Product name	1	20150929
e0b6c8be-f2bd-9f86-a9fc-3ed56ffaa814	Product name	3	20150910
c6fba691-a132-4ede-95c6-f8c6bd696636	Product name	1	20150902
c0200ab5-4954-454e-9676-30b741b245bd	Product name	1	20150730
89dac932-b90a-4410-9ab1-84c53e57de25	Product name	1	20150316
2a21311a-89e2-0e83-2ebd-117f9798b2b2	Product name	1	20140508
42f3c020-f1b3-89bc-7bdc-e1f10e680485	Product name	1	20140508
9007e8a7-ff50-f9b9-7945-f2a1deadd94e	Product name	1	20140508
96c2be53-8e44-452d-56a2-d255b2f1af2d	Product name	1	20140508
bf8bd5f7-495f-4022-2780-7ded7ea7ea44	Product name	1	20140508
e949165d-714d-e548-2b76-0cb5def16f30	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0280-1400-12	Alka-Seltzer Plus Cold Medicine Sparkling Original	2 in 1 POUCH	TABLET, EFFERVESCENT	2	9
0280-1400-12	Alka-Seltzer Plus Cold Medicine Sparkling Original	6 in 1 CARTON	TABLET, EFFERVESCENT	6	9
0280-1400-20	Alka-Seltzer Plus Cold Medicine Sparkling Original	10 in 1 CARTON	TABLET, EFFERVESCENT	10	9
0280-1400-20	Alka-Seltzer Plus Cold Medicine Sparkling Original	2 in 1 POUCH	TABLET, EFFERVESCENT	2	9
0280-1400-32	Alka-Seltzer Plus Cold Medicine Sparkling Original	2 in 1 POUCH	TABLET, EFFERVESCENT	2	9
0280-1400-32	Alka-Seltzer Plus Cold Medicine Sparkling Original	16 in 1 CARTON	TABLET, EFFERVESCENT	16	9
0280-1400-36	Alka-Seltzer Plus Cold Medicine Sparkling Original	18 in 1 CARTON	TABLET, EFFERVESCENT	18	9
0280-1400-36	Alka-Seltzer Plus Cold Medicine Sparkling Original	2 in 1 POUCH	TABLET, EFFERVESCENT	2	9
0280-1400-48	Alka-Seltzer Plus Cold Medicine Sparkling Original	24 in 1 CARTON	TABLET, EFFERVESCENT	24	9
0280-1400-48	Alka-Seltzer Plus Cold Medicine Sparkling Original	2 in 1 POUCH	TABLET, EFFERVESCENT	2	9
0280-1400-72	Alka-Seltzer Plus Cold Medicine Sparkling Original	2 in 1 POUCH	TABLET, EFFERVESCENT	2	9
0280-1400-72	Alka-Seltzer Plus Cold Medicine Sparkling Original	36 in 1 CARTON	TABLET, EFFERVESCENT	36	9

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0280-1400-36	EA - Each	0280-1400	d9ce5ae8-6625-47f9-ad92-12f7edef8e05	1	2018-12-13

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
ASPIRIN	ACTIVE INGREDIENT	R16CO5Y76E	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
CHLORPHENIRAMINE MALEATE	ACTIVE INGREDIENT	V1Q0O9OJ9Z	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
PHENYLEPHRINE BITARTRATE	ACTIVE INGREDIENT	27O3Q5ML57	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
ASPIRIN	ACTIVE MOIETY	R16CO5Y76E	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
CHLORPHENIRAMINE	ACTIVE MOIETY	3U6IO1965U	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
PHENYLEPHRINE	ACTIVE MOIETY	1WS297W6MV	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
ACESULFAME POTASSIUM	INACTIVE INGREDIENT	23OV73Q5G9	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
ANHYDROUS CITRIC ACID	INACTIVE INGREDIENT	XF417D3PSL	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
ASPARTAME	INACTIVE INGREDIENT	Z0H242BBR1	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
CALCIUM SILICATE	INACTIVE INGREDIENT	S4255P4G5M	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
DIMETHICONE	INACTIVE INGREDIENT	92RU3N3Y1O	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
DOCUSATE SODIUM	INACTIVE INGREDIENT	F05Q2T2JA0	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
MANNITOL	INACTIVE INGREDIENT	3OWL53L36A	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
POVIDONES	INACTIVE INGREDIENT	FZ989GH94E	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
SODIUM BENZOATE	INACTIVE INGREDIENT	OJ245FE5EU	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1
SODIUM BICARBONATE	INACTIVE INGREDIENT	8MDF5V39QO	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE CONSUMER CARE]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0280-1400	ALKA-SELTZER PLUS COLD MEDICINE SPARKLING ORIGINAL (ASPIRIN, CHLORPHENIRAMINE MALEATE, AND PHENYLEPHRINE BITARTRATE) TABLET, EFFERVESCENT [BAYER HEALTHCARE LLC.]	8	Current NDC, Legacy NDC, 12 package rows	20231205_78537dcf-b157-4b67-a8b2-5cb144815166.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 36 of 79 · 1,579 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
TEXACLEAR PAIN RELIEVER	CAFFEINE, CHOLINE SALICYLATE	GM Pharmaceuticals, INC	065bd10c-3bcf-486f-a49c-40544127007f	2025-10-15	Warnings	Exact identifier application number: M013
ACETAMINOPHEN 500 MG	ACETAMINOPHEN	ASCLEMED USA INC.	db8e6702-88ac-4db2-9dd8-7d0ed997c2b5	2025-10-14	Warnings	Exact identifier application number: M013
Pain Reliever Extra Strength	ACETAMINOPHEN	Walgreen Company	fa33f6ef-522b-4630-9716-92371d9cd24a	2025-10-14	Warnings	Exact identifier application number: M013
acetaminophen	ACETAMINOPHEN	Rite Aid Corporation	a8bb4f45-7a1a-4bf7-92ca-3afd508032f3	2025-10-09	Warnings	Exact identifier application number: M013
Pain Reliever	ACETAMINOPHEN	Health Pharma USA LLC	b15a7dcb-f143-4aea-8850-d0aacbf709b6	2025-10-09	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	PD-Rx Pharmaceuticals, Inc.	3f96aeb1-a533-4d36-9a1f-62fc094b6754	2025-10-08	Warnings	Exact identifier application number: M013
Headache Relief Extra Strength	ACETAMINOPHEN, ASPIRIN, CAFFEINE	Walgreens	f2eb9575-d527-44c7-aa5e-efabfd9a0278	2025-10-07	Warnings	Exact identifier application number: M013
Acetaminophen PM Extra Strength	ACETAMINOPHEN, DIPHENHYDRAMINE HCL	CHAIN DRUG MARKETING ASSOCIATION INC	bbc704e5-79f6-4c72-846b-cc30c5c43cb4	2025-10-07	Warnings	Exact identifier application number: M013
Aspirin Enteric Coated	ASPIRIN	CHAIN DRUG MARKETING ASSOCIATION INC	f1ce15a3-9824-4eb5-910a-39078165f385	2025-10-07	Warnings	Exact identifier application number: M013
BupropiDex	DEXTROMETHORPHAN HYDROBROMIDE	DXM Pharmacuetical, Inc.	90cc9bcd-7891-4324-a1f4-f6df7a0457e0	2025-10-06	Warnings	Exact identifier application number: M013
Dextabs	DEXTROMETHORPHAN HYDROBROMIDE	DXM Pharmacuetical, Inc.	71b567df-844a-4563-b85a-f4592233f37d	2025-10-06	Warnings	Exact identifier application number: M013
Acetaminophen, Aspirin and Caffeine	ACETAMINOPHEN, ASPIRIN AND CAFFEINE	Rising Pharma Holdings, Inc.	50f72713-50f5-4bab-9e96-b9fa73c9df1f	2025-10-06	Warnings	Exact identifier application number: M013
OneSsip Acetaminophen Oral Suspension Bubble Gum 5 mL	ACETAMINOPHEN 160 MG / 5 ML	MEDWISE LIFESCIENCES INC.	40507559-aee4-a603-e063-6394a90afc4f	2025-10-04	Warnings	Exact identifier application number: M013
Acetaminophen	ACETAMINOPHEN	NuCare Pharmaceuticals,Inc.	004c39cd-b4f4-1cae-e063-6394a90a0697	2025-10-03	Warnings	Exact identifier application number: M013
Pain Reliever	ACETAMINOPHEN	Family Dollar (FAMILY WELLNESS)	43573e35-6776-446e-aa28-75c8edc5b98d	2025-10-03	Warnings	Exact identifier application number: M013
Pain Reliever	ACETAMINOPHEN	Family Dollar (FAMILY WELLNESS)	f8e5fab4-1212-4c60-a160-9b782f76a198	2025-10-03	Warnings	Exact identifier application number: M013
CVS Acetaminophen	ACETAMINOPHEN	CVS Pharmacy	3d71a0aa-5e03-0bdc-e063-6294a90a6634	2025-10-02	Warnings	Exact identifier application number: M013
Chewable Aspirin	ASPIRIN	Chain Drug Marketing Association, Inc.	cc865351-34e8-4e8e-b8bf-23336c45bc61	2025-10-02	Warnings	Exact identifier application number: M013
ACETAMINOPHEN	ACETAMINOPHEN	Bryant Ranch Prepack	8e40f8f1-03c5-444b-8b5e-4532c3146e47	2025-10-02	Warnings	Exact identifier application number: M013
ASPIRIN 325 MG EC	ASPIRIN	Proficient Rx LP	9f9355f7-024a-4adc-bb4c-2d9c0dd0cb77	2025-10-01	Warnings	Exact identifier application number: M013

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
R16CO5Y76E	ASPIRIN	50-78-2	ASPIRIN
V1Q0O9OJ9Z	CHLORPHENIRAMINE MALEATE	113-92-8	CHLORPHENIRAMINE MALEATE
27O3Q5ML57	PHENYLEPHRINE BITARTRATE	17162-39-9	PHENYLEPHRINE BITARTRATE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1536840	aspirin 325 MG / chlorpheniramine maleate 2 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet	PSN	78537dcf-b157-4b67-a8b2-5cb144815166	9
1536840	aspirin 325 MG / chlorpheniramine maleate 2 MG / phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet	SCD	78537dcf-b157-4b67-a8b2-5cb144815166	9
1536840	ASA 325 MG / Chlorpheniramine Maleate 2 MG / Phenylephrine bitartrate 7.8 MG Effervescent Oral Tablet	SY	78537dcf-b157-4b67-a8b2-5cb144815166	9

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0280-1400-12	00280140012	2 in 1 POUCH						Historical
0280-1400-20	00280140020	10 in 1 CARTON						Historical
0280-1400-32	00280140032	16 POUCH in 1 CARTON (0280-1400-32) / 2 TABLET, EFFERVESCENT in 1 POUCH	16 pouch	2008-04-10	0000-00-00	No	No	Current
0280-1400-36	00280140036	18 in 1 CARTON						Historical
0280-1400-48	00280140048	24 in 1 CARTON						Historical
0280-1400-72	00280140072	2 in 1 POUCH						Historical

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Alka-Seltzer Plus ® Cold Medicine Sparkling Original	Bayer HealthCare LLC.	2025-12-04	HUMAN OTC DRUG LABEL	9
ALKA SELTZER PLUS 2'S BLISTER PACK	JC World Bell Wholesale Co., Inc.	2023-10-27	HUMAN OTC DRUG LABEL	4
Alka Seltzer Plus Cold	Navajo Manufacturing Company Inc.	2022-07-28	HUMAN OTC DRUG LABEL	3
ALKA SELTZER PLUS 1'S BLISTER PACK	JC World Bell Wholesale Co., Inc.	2022-04-11	HUMAN OTC DRUG LABEL	3
Alka-Seltzer Plus ® Cold Medicine Sparkling Original	R J General Corporation	2018-08-06	HUMAN OTC DRUG LABEL	2