Overnight Cold and Flu

Product NDC: 0363-6980
11-digit product format: 003636980
Labeler code: 0363
Product ID: 0363-6980_446afe14-2e44-2cf8-e063-6394a90af70e
Type: HUMAN OTC DRUG
Nonproprietary name: Acetaminophen, Dextromethorphan HBr, Triprolidine HCl
Dosage form: SOLUTION
Route: ORAL
Labeler: WALGREENS CO
Application: M010
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2020-01-28
Substance: ACETAMINOPHEN; DEXTROMETHORPHAN HYDROBROMIDE; TRIPROLIDINE HYDROCHLORIDE
Active strength: 650; 20; 2.5 mg/20mL; mg/20mL; mg/20mL
Pharmacologic classes: Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Overnight Cold and Flu
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ACETAMINOPHEN	650 mg/20mL
DEXTROMETHORPHAN HYDROBROMIDE	20 mg/20mL
TRIPROLIDINE HYDROCHLORIDE	2.5 mg/20mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
362O9ITL9D	Internal UNII lookup
9D2RTI9KYH	Internal UNII lookup
YAN7R5L890	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2173667	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
807e8ace-2901-4c5f-96dc-04c755484b95	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
bf324df6-7127-7deb-def5-2681c136cd03	Product name	3	20250325
43a1ed49-eae2-4840-8075-cb4b33478540	Product name	1	20230425
ba088a92-ab5e-b2d4-e908-f5ea691b7587	Product name	7	20210201
c5cd4727-ac49-4409-82b1-5bd8006c3ec7	Product name	1	20171122
30c51294-7ae9-8007-7de6-58222684a0be	Product name	1	20140508
76633df9-0d59-4b88-03ed-21dee1b966f8	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
0363-6980-06	Overnight Cold and Flu	180 mL in 1 BOTTLE	SOLUTION	180		7

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0363-6980	OVERNIGHT COLD AND FLU (ACETAMINOPHEN, DEXTROMETHORPHAN HBR, TRIPROLIDINE HCL) SOLUTION [WALGREENS CO]	6	Current NDC, Legacy NDC, 1 package rows	20241113_807e8ace-2901-4c5f-96dc-04c755484b95.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 9 of 12 · 236 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
RIGHT REMEDIES Maximum Strength Nighttime Sleep-Aid Softgel	DIPHENHYDRAMINE HYDROCHLORIDE	Strive Pharmaceuticals Inc.	2d64f5c2-dfa9-e5f5-e063-6294a90a0711	2025-03-19	Warnings	Exact identifier application number: M010
Sleep Aid Maximum Strength	DIPHENHYDRAMINE HCL	Harris Teeter, LLC	322a71bb-fc68-4a03-8a24-20cbdbe6d91b	2025-03-13	Warnings	Exact identifier application number: M010
REVASOL SLEEP AID	DIPHENHYDRAMINE HCL	Rnv LLC	30131010-be70-c940-e063-6394a90a190a	2025-03-11	Warnings	Exact identifier application number: M010
Nighttime Sleep Aid	DIPHENHYDRAMINE HCL	L.N.K. International, Inc.	1a7189ba-2d52-44fc-83a4-b9f6156c62ff	2025-03-07	Warnings	Exact identifier application number: M010
meijer NIGHTTIME Sleep Aid SOFTGEL	DIPHENHYDRAMINE HYDROCHLORIDE	Meijer, Inc.	1bede4cd-bf55-8b84-e063-6394a90aa5c9	2025-02-19	Warnings	Exact identifier application number: M010
PHARBEDRYL	DIPHENHYDRAMINE HCL 50MG	Ulai Health LLC	135293fb-5674-4638-be55-b968cf51257e	2025-01-20	Warnings	Exact identifier application number: M010
Allergy Relief 25 mg	DIPHENHYDRAMINE HCL 25MG	Ulai Health LLC	751f13d4-c4d6-47a5-b40d-1563de08c048	2025-01-12	Warnings	Exact identifier application number: M010
RoboCough	DEXTROMETHORPHAN HBR	DXM Pharmacuetical, Inc.	32fa7a09-8624-44c1-b9e4-8a8f0594292b	2025-01-10	Warnings	Exact identifier application number: M010
SleepAid (Diphenhydramine HCL)	DIPHENHYDRAMINE HCL	APNAR PHARMA LP	faaf5d51-d81d-3acc-e053-6294a90ae08f	2025-01-09	Warnings	Exact identifier application number: M010
Diphenhydramine Hydrochloride	DIPHENHYDRAMINE HYDROCHLORIDE	Strive Pharmaceuticals Inc.	971515fa-b4d2-1197-e053-2995a90a838d	2025-01-03	Warnings	Exact identifier application number: M010
Nighttime Sleep-Aid Softgel	DIPHENHYDRAMINE HYDROCHLORIDE	CVS PHARMACY, INC	8b0fa259-6702-4667-bac6-f7d0b0839ae0	2025-01-01	Warnings	Exact identifier application number: M010
Sleep Aid Nighttime	DIPHENHYDRAMINE HYDROCHLORIDE	TOPCO ASSOCIATES LLC	9f1c078d-e537-4ec0-8ae9-54c98282be29	2024-12-31	Warnings	Exact identifier application number: M010
Discount Drugmart Nighttime Sleep-Aid	DIPHENHYDRAMINE HCL	Discount Drug Mart, Inc	d6d77c2e-42b3-48f0-a662-3872155ef34d	2024-12-18	Warnings	Exact identifier application number: M010
Kroger Nighttime Sleep-Aid	DIPHENHYDRAMINE HCL	THE KROGER CO	98437a72-1b98-4301-b92f-0c17b305cf59	2024-12-18	Warnings	Exact identifier application number: M010
equate nighttime sleep aid	DIPHENHYDRAMINE HYDROCHLORIDE	WALMART INC.	6e162152-b414-470c-b146-649d99870577	2024-12-17	Warnings	Exact identifier application number: M010
Quality Choice Nighttime Sleep-Aid	DIPHENHYDRAMINE HYDROCHLORIDE	Chain Drug Marketing Association, Inc.	e8b2858b-a737-c500-e053-2995a90adba6	2024-12-16	Warnings	Exact identifier application number: M010
Nighttime Sleep Aid	DIPHENHYDRAMINE HYDROCHLORIDE	Strive Pharmaceuticals Inc.	f99cc210-b946-42a2-9164-8aa5308c5418	2024-12-11	Warnings	Exact identifier application number: M010
CalmCo Sleep Aid Gummy Bite	DIPHENHYDRAMINE HCL	CalmCo LLC	0c534cbd-40e6-8af0-e063-6394a90a5605	2024-12-07	Warnings	Exact identifier application number: M010
Somnapure Clinical Strength	DIPHENHYDRAMINE HYDROCHLORIDE	Force Factor Brands LLC	063517c0-bcb1-46dd-85f1-bbb2f24274ef	2024-12-06	Warnings	Exact identifier application number: M010
Diphenhydramine Hydrochloride	DIPHENHYDRAMINE HYDROCHLORIDE	AAA Pharmaceutical, Inc.	c280cf02-ebb2-4847-a66d-d02aff3ea0c9	2024-12-02	Warnings	Exact identifier application number: M010

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
362O9ITL9D	ACETAMINOPHEN	103-90-2	ACETAMINOPHEN
9D2RTI9KYH	DEXTROMETHORPHAN HYDROBROMIDE	6700-34-1	DEXTROMETHORPHAN HYDROBROMIDE
YAN7R5L890	TRIPROLIDINE HYDROCHLORIDE	6138-79-0	TRIPROLIDINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2173667	acetaminophen 650 MG / dextromethorphan HBr 20 MG / triprolidine HCl 2.5 MG in 20 mL Oral Solution	PSN	807e8ace-2901-4c5f-96dc-04c755484b95	7
2173667	acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution	SCD	807e8ace-2901-4c5f-96dc-04c755484b95	7
2173667	acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / triprolidine hydrochloride 2.5 MG per 20 mL Oral Solution	SY	807e8ace-2901-4c5f-96dc-04c755484b95	7
2173667	APAP 32.5 MG/ML / Dextromethorphan Hydrobromide 1 MG/ML / Triprolidine Hydrochloride 0.125 MG/ML Oral Solution	SY	807e8ace-2901-4c5f-96dc-04c755484b95	7

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0363-6980-06	00363698006	180 mL in 1 BOTTLE (0363-6980-06)	180 ml	2020-01-28	0000-00-00	No	No	Current