Overnight Cold and Flu

Product NDC: 0363-6980
11-digit product format: 003636980
Labeler code: 0363
Product ID: 0363-6980_446afe14-2e44-2cf8-e063-6394a90af70e
Type: HUMAN OTC DRUG
Nonproprietary name: Acetaminophen, Dextromethorphan HBr, Triprolidine HCl
Dosage form: SOLUTION
Route: ORAL
Labeler: WALGREENS CO
Application: M010
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2020-01-28
Substance: ACETAMINOPHEN; DEXTROMETHORPHAN HYDROBROMIDE; TRIPROLIDINE HYDROCHLORIDE
Active strength: 650; 20; 2.5 mg/20mL; mg/20mL; mg/20mL
Pharmacologic classes: Sigma-1 Agonist [EPC], Sigma-1 Receptor Agonists [MoA], Uncompetitive N-methyl-D-aspartate Receptor Antagonist [EPC], Uncompetitive NMDA Receptor Antagonists [MoA]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Overnight Cold and Flu
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
ACETAMINOPHEN	650 mg/20mL
DEXTROMETHORPHAN HYDROBROMIDE	20 mg/20mL
TRIPROLIDINE HYDROCHLORIDE	2.5 mg/20mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
362O9ITL9D	Internal UNII lookup
9D2RTI9KYH	Internal UNII lookup
YAN7R5L890	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
2173667	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
807e8ace-2901-4c5f-96dc-04c755484b95	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
bf324df6-7127-7deb-def5-2681c136cd03	Product name	3	20250325
43a1ed49-eae2-4840-8075-cb4b33478540	Product name	1	20230425
ba088a92-ab5e-b2d4-e908-f5ea691b7587	Product name	7	20210201
c5cd4727-ac49-4409-82b1-5bd8006c3ec7	Product name	1	20171122
30c51294-7ae9-8007-7de6-58222684a0be	Product name	1	20140508
76633df9-0d59-4b88-03ed-21dee1b966f8	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
0363-6980-06	Overnight Cold and Flu	180 mL in 1 BOTTLE	SOLUTION	180		7

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0363-6980	OVERNIGHT COLD AND FLU (ACETAMINOPHEN, DEXTROMETHORPHAN HBR, TRIPROLIDINE HCL) SOLUTION [WALGREENS CO]	6	Current NDC, Legacy NDC, 1 package rows	20241113_807e8ace-2901-4c5f-96dc-04c755484b95.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 8 of 12 · 236 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
dg health sleep aid	DIPHENHYDRAMINE HCL	Dolgencorp, LLC	4c266acb-49ae-4d04-8602-0df35b22874a	2025-07-10	Warnings	Exact identifier application number: M010
NIGHT TIME SLEEP-AID	DIPHENHYDRAMINE HCL	Advanced Rx LLC	07c69e63-deb1-4607-9f7f-1cf0cd05cc82	2025-07-02	Warnings	Exact identifier application number: M010
Rest Simply	DIPHENHYDRAMINE HYDROCHLORIDE	DISCOUNT DRUG MART	896ae7b8-cb8d-1aaa-e053-2a95a90a4e1a	2025-06-30	Warnings	Exact identifier application number: M010
Nighttime Sleep Aid	DIPHENHYDRAMINE HCL	TOP CARE (Topco Associates LLC)	027d7eff-6c83-40f1-9716-231637cdbeba	2025-06-12	Warnings	Exact identifier application number: M010
Nighttime Sleep Aid maximum strength	DIPHENHYDRAMINE HCL	Cardinal Health (Leader) 70000	546e4fda-6eb2-4358-840e-e2473bf7f352	2025-06-03	Warnings	Exact identifier application number: M010
Simply Sleep	DIPHENHYDRAMINE HYDROCHLORIDE	Kenvue Brands LLC	37c606b0-04d5-49f0-886a-3ee2c9b0e9cc	2025-06-02	Warnings	Exact identifier application number: M010
Sleep Aid Maximum Strength	DIPHENHYDRAMINE HCL	WinCo Foods, LLC	e9bc5a16-b1fc-4585-8f3b-30ccf4300492	2025-05-30	Warnings	Exact identifier application number: M010
Nighttime Sleep Aid	DIPHENHYDRAMINE HCL	Care One (Retail Business Services, LLC.)	51e633a8-5bfc-4ff9-816f-3bc22b8a5c4c	2025-05-23	Warnings	Exact identifier application number: M010
Nighttime Sleep Aid Maximum Strength	DIPHENHYDRAMINE HCL	Care One (Retail Business Services, LLC.)	536cd7d6-a470-4614-89c8-6c3ada582a90	2025-05-23	Warnings	Exact identifier application number: M010
Nighttime Sleep Aid	DIPHENHYDRAMINE HCL	Cardinal Health (Leader) 70000	133d6f38-9de7-4104-8175-3933b263afe0	2025-05-16	Warnings	Exact identifier application number: M010
Nighttime Sleep-aid	DIPHENHYDRAMINE HCL	NORTHEAST PHARMA	d2062094-d1b5-38ab-e053-2995a90a5670	2025-05-15	Warnings	Exact identifier application number: M010
Nighttime Sleep-aid	DIPHENHYDRAMINE HCL	Geri-Care Pharmaceutical Corp	0fce381f-28ef-4591-a569-c5d599a3b95f	2025-05-14	Warnings	Exact identifier application number: M010
Rest Simply	DIPHENHYDRAMINE HYDROCHLORIDE	Chain Drug Marketing Association	54bdb6bc-622c-412a-8365-a1b1c968e13e	2025-05-01	Warnings	Exact identifier application number: M010
Sleep Aid Nighttime	DIPHENHYDRAMINE HCL	United Natural Foods, Inc. dba UNFI	217a211e-b8bf-4119-a094-0e5e733d0b18	2025-04-21	Warnings	Exact identifier application number: M010
Sleep Aid	DIPHENHYDRAMINE HCL	QUALITY CHOICE (Chain Drug Marketing Association)	25f32a1c-0687-45e9-8142-96cf63599090	2025-04-03	Warnings	Exact identifier application number: M010
Sleep Aid	DIPHENHYDRAMINE HCL	FSA Store Inc. (Caring Mills)	9d32a3a1-9528-4de4-9fd1-1d01a1ad93e9	2025-03-28	Warnings	Exact identifier application number: M010
Nighttime Sleep Aid	DIPHENHYDRAMINE HCL	WR Group, Inc.	d28d0f6d-8029-4e31-b417-4f8f864d840e	2025-03-28	Warnings	Exact identifier application number: M010
Sleep Aid NightTime	DIPHENHYDRAMINE HCL	P & L Development, LLC	4144b1a6-aeae-4560-a997-b07206d80350	2025-03-24	Warnings	Exact identifier application number: M010
Sleep Aid	DIPHENHYDRAMINE HCL	Strategic Sourcing Services LLC	a512413c-639b-4846-b016-332a78b50ab7	2025-03-21	Warnings	Exact identifier application number: M010
Diphenhydramine HCl	DIPHENHYDRAMINE HCL	PD-Rx Pharmaceuticals, Inc.	1ee41c86-6767-43ca-a5bb-fc685fa662cd	2025-03-20	Warnings	Exact identifier application number: M010

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
362O9ITL9D	ACETAMINOPHEN	103-90-2	ACETAMINOPHEN
9D2RTI9KYH	DEXTROMETHORPHAN HYDROBROMIDE	6700-34-1	DEXTROMETHORPHAN HYDROBROMIDE
YAN7R5L890	TRIPROLIDINE HYDROCHLORIDE	6138-79-0	TRIPROLIDINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
2173667	acetaminophen 650 MG / dextromethorphan HBr 20 MG / triprolidine HCl 2.5 MG in 20 mL Oral Solution	PSN	807e8ace-2901-4c5f-96dc-04c755484b95	7
2173667	acetaminophen 32.5 MG/ML / dextromethorphan hydrobromide 1 MG/ML / triprolidine hydrochloride 0.125 MG/ML Oral Solution	SCD	807e8ace-2901-4c5f-96dc-04c755484b95	7
2173667	acetaminophen 650 MG / dextromethorphan hydrobromide 20 MG / triprolidine hydrochloride 2.5 MG per 20 mL Oral Solution	SY	807e8ace-2901-4c5f-96dc-04c755484b95	7
2173667	APAP 32.5 MG/ML / Dextromethorphan Hydrobromide 1 MG/ML / Triprolidine Hydrochloride 0.125 MG/ML Oral Solution	SY	807e8ace-2901-4c5f-96dc-04c755484b95	7

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0363-6980-06	00363698006	180 mL in 1 BOTTLE (0363-6980-06)	180 ml	2020-01-28	0000-00-00	No	No	Current