Doxepin Hydrochloride

Product NDC
0378-8117
Requested package NDC
0378-8117-45
11-digit product format
003788117
Labeler code
0378
Product ID
0378-8117_b4771ea7-c19b-4182-bb23-c1473ab583fa
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Doxepin Hydrochloride
Dosage form
CREAM
Route
TOPICAL
Labeler
Mylan Pharmaceuticals Inc.
Application
NDA020126
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
2019-01-04
Substance
DOXEPIN HYDROCHLORIDE
Active strength
50 mg/g
Pharmacologic classes
Tricyclic Antidepressant [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020126-001ZONALONDOXEPIN HYDROCHLORIDE5%CREAM / TOPICALABRLD, RS1994-04-01

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N020126-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-016a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-0103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-012680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-015bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-0179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-011e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-018072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-015c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-015d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-014b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-0174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-01bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-01782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-0187673890dc5c…
2021-03-12 10:30 UTC2021-03N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-015aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-018869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-01c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-013f01610625f2…
2019-09-15 20:21 UTC2019-09N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-01b00525d2431f…
2019-07-19 19:46 UTC2019-07N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-01ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-016a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-011c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-019b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-013f0d92c62455…
2023-05-13 08:27 UTC2023-05N020126-001ZONALON5%CREAM / TOPICALABRLD, RS1994-04-01053a50430f4f…
2023-01-26 05:58 UTC2023-01N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-013bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-013a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-01f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-01e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N020126-001ZONALON5%CREAM / TOPICALRLD, RS1994-04-01cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N020126-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020126-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020126-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020126-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020126-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020126-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020126-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020126-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020126-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020126-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020126-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020126-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020126-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020126-001AB18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020126-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020126-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020126-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020126-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020126-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020126-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020126-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N020126-001AB1053a50430f4f…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N020126-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Doxepin Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DOXEPIN HYDROCHLORIDE50 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
3U9A0FE9N5Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1000091Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
b4771ea7-c19b-4182-bb23-c1473ab583faAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
f6fcd62d-384f-5faa-05d7-c5d5903c6c43Product name420250515
3d5463a5-d368-9c2b-b40c-0f2b688e406eProduct name920240805
750bc85a-c69c-4145-a865-3f1124677d16Product name320240321
eda77195-5c17-5c7f-a6a7-8c80d2f8ae5fProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0378-8117-45Doxepin Hydrochloride1 in 1 CARTONCREAM11
0378-8117-45Doxepin Hydrochloride45 g in 1 TUBECREAM451

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0378-8117-45GM - Gram0378-811731d0561d-8dea-4d12-9784-49e8bd2f20f012019-02-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0378-8117DOXEPIN HYDROCHLORIDE CREAM [MYLAN PHARMACEUTICALS INC.]1Current NDC, Legacy NDC, 2 package rows20190109_b4771ea7-c19b-4182-bb23-c1473ab583fa.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
PRUDOXINDOXEPIN HYDROCHLORIDEMylan Pharmaceuticals Inc.ca53346b-8ab3-4722-98f6-cf272706d3fa2017-06-29Warnings, Adverse reactionsExact identifier
application applno (NDA): 020126
application number: NDA020126
ZonalonDOXEPIN HYDROCHLORIDEMylan Pharmaceuticals Inc.5f302247-525e-4acc-852b-00eb1d79af4b2017-06-14Warnings, Adverse reactionsExact identifier
application applno (NDA): 020126
application number: NDA020126
Doxepin HydrochlorideDOXEPIN HYDROCHLORIDEMylan Pharmaceuticals Inc.b4771ea7-c19b-4182-bb23-c1473ab583fa2017-05-24Warnings, Adverse reactionsExact identifier
application applno (NDA): 020126
application number: NDA020126
ndc (package): 0378-8117-45
ndc (product): 0378-8117
ndc11 (package): 00378811745

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1000091doxepin HCl 5 % Topical CreamPSNb4771ea7-c19b-4182-bb23-c1473ab583fa1
1000091doxepin hydrochloride 50 MG/ML Topical CreamSCDb4771ea7-c19b-4182-bb23-c1473ab583fa1
1000091doxepin hydrochloride 5 % Topical CreamSYb4771ea7-c19b-4182-bb23-c1473ab583fa1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0378-8117-45003788117451 TUBE in 1 CARTON (0378-8117-45) / 45 g in 1 TUBE1 tube2019-01-040000-00-00NoNoCurrent