Acyclovir

Product NDC
0378-8700
11-digit product format
003788700
Labeler code
0378
Product ID
0378-8700_30e195ea-26e4-4747-9e7e-b85e0f6f68d8
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
acyclovir
Dosage form
OINTMENT
Route
TOPICAL
Labeler
Mylan Pharmaceuticals Inc.
Application
ANDA202459
Marketing category
ANDA
Marketing start
2013-04-03
Marketing end
0000-00-00
Substance
ACYCLOVIR
Active strength
50 mg/g
Pharmacologic classes
DNA Polymerase Inhibitors [MoA],Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC],Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor [EPC],Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor [EPC],Nucleoside Analog [EXT]
NDC exclude flag
No
Listing certified through
2022-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct0378-8700DDiscontinued by firm2026-08-10
excluded packagepackage0378-87000378-8700-06DDiscontinued by firm2026-08-10
excluded packagepackage0378-87000378-8700-49DDiscontinued by firm2026-08-10

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 4 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage0378-8700-06d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage0378-8700-49d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage0378-8700-06f5e01cc5f278…a2eaf40c39c3…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A202459-001ACYCLOVIRACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A202459-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-0331067a03dcf5…
2025-08-23 18:47 UTC2025-08A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-036a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-0303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-032680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-035bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-0379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-031e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-038072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-035c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-035d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-034b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-0374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-0387673890dc5c…
2021-03-12 10:30 UTC2021-03A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-035aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-038869cabd3fbd…
2020-11-12 02:37 UTC2020-11A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03c0c555d07b60…
2019-12-14 00:12 UTC2019-12A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-033f01610625f2…
2019-09-15 20:21 UTC2019-09A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03b00525d2431f…
2019-07-19 19:46 UTC2019-07A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-036a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-031c564ffb4f44…
2023-12-20 04:57 UTC2023-12A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-039b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-033f0d92c62455…
2023-05-13 08:27 UTC2023-05A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03053a50430f4f…
2023-01-26 05:58 UTC2023-01A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-033bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-033a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A202459-001ACYCLOVIR5%OINTMENT / TOPICALAB2013-04-03cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A202459-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202459-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A202459-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202459-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202459-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202459-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202459-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202459-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202459-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202459-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202459-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202459-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202459-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202459-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202459-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202459-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202459-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202459-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202459-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202459-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202459-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A202459-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A202459-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A202459-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A202459-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A202459-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A202459-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A202459-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A202459-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A202459-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A202459-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A202459-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A202459-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A202459-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A202459-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A202459-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A202459-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A202459-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A202459-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A202459-001AB1cb3db0bc1861…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0378-8700-06GM - Gram0378-87004c8fa599-2851-483a-960a-0d27ef49b4af12013-05-02
0378-8700-49GM - Gram0378-8700537cbb9f-9ad5-4bc0-896e-77c56e6ab2ec12013-06-04

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ACYCLOVIRACTIVE INGREDIENTX4HES1O11FACYCLOVIR OINTMENT [MYLAN PHARMACEUTICALS INC.]5
ACYCLOVIRACTIVE MOIETYX4HES1O11FACYCLOVIR OINTMENT [MYLAN PHARMACEUTICALS INC.]5
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1AACYCLOVIR OINTMENT [MYLAN PHARMACEUTICALS INC.]5
ACYCLOVIRACTIVE INGREDIENTX4HES1O11FACYCLOVIR OINTMENT [MYLAN INSTITUTIONAL INC.]2
ACYCLOVIRACTIVE MOIETYX4HES1O11FACYCLOVIR OINTMENT [MYLAN INSTITUTIONAL INC.]2
POLYETHYLENE GLYCOLSINACTIVE INGREDIENT3WJQ0SDW1AACYCLOVIR OINTMENT [MYLAN INSTITUTIONAL INC.]2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0378-8700ACYCLOVIR OINTMENT [MYLAN PHARMACEUTICALS INC.]12Legacy NDC20250101_ce3d5e8b-9401-40be-8ce7-4ea42113f4ab.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AcyclovirACYCLOVIRAryeh Pharma Corpf60cc0c2-e0fe-406a-b5c0-90bc4b566bb32026-05-01Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202459
application number: ANDA202459

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0378-8700-06003788700061 TUBE in 1 CARTON (0378-8700-06) > 15 g in 1 TUBE1 tube2013-04-030000-00-00NoNoCurrent
0378-8700-49003788700491 TUBE in 1 CARTON (0378-8700-49) > 30 g in 1 TUBE1 tube2013-04-030000-00-00NoNoCurrent