Suprane

Product NDC: 0404-9961
11-digit product format: 004049961
Labeler code: 0404
Product ID: 0404-9961_59b77741-115b-42dc-85a2-35e8fd9e2ec2
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Desflurane
Dosage form: LIQUID
Route: RESPIRATORY (INHALATION)
Labeler: Henry Schein, Inc.
Application: NDA020118
Marketing category: NDA
Marketing start: 2022-01-12
Substance: DESFLURANE
Active strength: 240 mL/240mL
Pharmacologic classes: General Anesthesia [PE], General Anesthetic [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N020118-001	SUPRANE	DESFLURANE	100%	LIQUID / INHALATION		RLD, RS	1992-09-18

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-08-18 06:07:40	2026-07	N020118-001	SUPRANE	100%	LIQUID / INHALATION		RLD, RS	1992-09-18	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`e64feba35796…`

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N020118-001	AN	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020118-001	AN	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N020118-001	AN	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020118-001	AN	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020118-001	AN	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020118-001	AN	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020118-001	AN	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020118-001	AN	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020118-001	AN	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N020118-001	AN	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020118-001	AN	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020118-001	AN	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020118-001	AN	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N020118-001	AN	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N020118-001	AN	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N020118-001	AN	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N020118-001	AN	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N020118-001	AN	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N020118-001	AN	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N020118-001	AN	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N020118-001	AN	1	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N020118-001	AN	1	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N020118-001	AN	1	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N020118-001	AN	1	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N020118-001	AN	1	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N020118-001	AN	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N020118-001	AN	1	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N020118-001	AN	1	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N020118-001	AN	1	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N020118-001	AN	1	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N020118-001	AN	1	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N020118-001	AN	1	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N020118-001	AN	1	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N020118-001	AN	1	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N020118-001	AN	1	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N020118-001	AN	1	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N020118-001	AN	1	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N020118-001	AN	1	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N020118-001	AN	1	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N020118-001	AN	1	`cb3db0bc1861…`

Additional Listing Data#

Finished product: Yes
Brand name base: Suprane
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DESFLURANE	240 mL/240mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
CRS35BZ94Q	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
208919	Internal RxNorm lookup
562366	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
fe60a7eb-08e5-4869-98ba-7cc2b17e8491	Product name	1	20180529

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
0404-9961-25	Suprane	1 in 1 BAG	LIQUID	1		7
0404-9961-25	Suprane	240 mL in 1 BOTTLE	LIQUID	240		7

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0404-9961	SUPRANE (DESFLURANE) LIQUID [HENRY SCHEIN, INC.]	6	Current NDC, Legacy NDC, 2 package rows	20241220_a3e4c8e5-bff0-4a8f-8401-e9866c846ee2.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Suprane	DESFLURANE	Henry Schein, Inc.	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	2026-07-15	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020118 application number: NDA020118 ndc (product): 0404-9961
SUPRANE	DESFLURANE	Baxter Healthcare Corporation	7f977eb6-c7c4-4dc5-ab3b-07414dbe5da5	2025-10-14	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020118 application number: NDA020118
SUPRANE	DESFLURANE	Baxter Healthcare Corporation	3fe3d468-d283-4dd0-a1a7-29291a9b2d0b	2025-10-14	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020118 application number: NDA020118
Suprane	DESFLURANE	Baxter Healthcare Corporation	efbb228b-7b38-4176-8bae-826103178c35	2025-10-14	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020118 application number: NDA020118

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
CRS35BZ94Q	DESFLURANE	57041-67-5	DESFLURANE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
562366	desflurane 100 % Inhalation Solution	PSN	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	7
208919	Suprane 100 % Inhalation Solution	PSN	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	7
208919	desflurane 1000 MG/ML Inhalation Solution [Suprane]	SBD	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	7
562366	desflurane 1000 MG/ML Inhalation Solution	SCD	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	7
562366	desflurane 100 % Inhalation Solution	SY	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	7
562366	desflurane 99 % Inhalation Solution	SY	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	7
208919	Suprane 1 ML/ML Inhalation Solution	SY	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	7
208919	Suprane 100 % Inhalation Solution	SY	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	7

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
0404-9961-25	00404996125	1 BOTTLE in 1 BAG (0404-9961-25) / 240 mL in 1 BOTTLE	1 bottle	2022-01-12	0000-00-00	No	No	Current