Suprane

Product NDC: 10019-644
11-digit product format: 100190644
Labeler code: 10019
Product ID: 10019-644_ec545337-e75b-46c5-981a-f49cea274749
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: DESFLURANE
Dosage form: LIQUID
Route: RESPIRATORY (INHALATION)
Labeler: Baxter Healthcare Corporation
Application: NDA020118
Marketing category: NDA
Marketing start: 1992-09-18
Substance: DESFLURANE
Active strength: 240 mL/240mL
Pharmacologic classes: General Anesthesia [PE], General Anesthetic [EPC]
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	10019-644	10019-644-24	D	Discontinued by firm		2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 1 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Archive	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	10019-644	10019-644-24	D	Discontinued by firm		excluded / ndc_excluded.zip	`d630ba8d3edf…`	`732f749b63fb…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N020118-001	SUPRANE	DESFLURANE	100%	LIQUID / INHALATION		RLD, RS	1992-09-18

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-08-18 06:07:40	2026-07	N020118-001	SUPRANE	100%	LIQUID / INHALATION		RLD, RS	1992-09-18	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N020118-001	SUPRANE	100%	LIQUID / INHALATION	AN	RLD, RS	1992-09-18	`e64feba35796…`

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N020118-001	AN	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N020118-001	AN	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N020118-001	AN	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N020118-001	AN	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N020118-001	AN	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N020118-001	AN	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N020118-001	AN	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N020118-001	AN	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N020118-001	AN	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N020118-001	AN	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N020118-001	AN	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N020118-001	AN	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N020118-001	AN	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N020118-001	AN	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N020118-001	AN	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N020118-001	AN	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N020118-001	AN	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N020118-001	AN	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N020118-001	AN	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N020118-001	AN	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N020118-001	AN	1	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N020118-001	AN	1	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N020118-001	AN	1	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N020118-001	AN	1	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N020118-001	AN	1	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N020118-001	AN	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N020118-001	AN	1	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N020118-001	AN	1	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N020118-001	AN	1	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N020118-001	AN	1	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N020118-001	AN	1	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N020118-001	AN	1	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N020118-001	AN	1	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N020118-001	AN	1	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N020118-001	AN	1	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N020118-001	AN	1	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N020118-001	AN	1	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N020118-001	AN	1	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N020118-001	AN	1	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N020118-001	AN	1	`cb3db0bc1861…`

Additional Listing Data#

Finished product: Yes
Brand name base: Suprane
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DESFLURANE	240 mL/240mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
CRS35BZ94Q	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
208919	Internal RxNorm lookup
562366	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
efbb228b-7b38-4176-8bae-826103178c35	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
fe60a7eb-08e5-4869-98ba-7cc2b17e8491	Product name	1	20180529

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
10019-644-24	Suprane	6 in 1 CARTON	LIQUID	6	17
10019-644-34	Suprane	6 in 1 CARTON	LIQUID	6	17
10019-644-60	Suprane	240 mL in 1 BOTTLE, GLASS	LIQUID	240	17
10019-644-64	Suprane	240 mL in 1 BOTTLE	LIQUID	240	17

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
10019-644-24	ML - Milliliter	10019-644	1dec2694-dc8c-4df0-a2ab-76c071744843	1	2012-07-24
10019-644-34	ML - Milliliter	10019-644	bb74514b-0e3e-4763-81f9-5c6e68b0e8b9	1	2013-08-02
10019-644-60	ML - Milliliter	10019-644	e11ae227-5c11-47fe-8e49-83e960cd2d2d	1	2012-07-24
10019-644-64	ML - Milliliter	10019-644	f891c0ce-27fd-4378-8307-bfacdca5c8b2	1	2015-10-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version	Uploaded
DESFLURANE	ACTIVE INGREDIENT	CRS35BZ94Q	SUPRANE (DESFLURANE) LIQUID [BAXTER HEALTHCARE CORPORATION]	5
DESFLURANE	ACTIVE MOIETY	CRS35BZ94Q	SUPRANE (DESFLURANE) LIQUID [BAXTER HEALTHCARE CORPORATION]	5

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
10019-644	SUPRANE (DESFLURANE) LIQUID [BAXTER HEALTHCARE CORPORATION]	14	Current NDC, Legacy NDC, 4 package rows	20240517_efbb228b-7b38-4176-8bae-826103178c35.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 4 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Suprane	DESFLURANE	Henry Schein, Inc.	a3e4c8e5-bff0-4a8f-8401-e9866c846ee2	2026-07-15	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020118 application number: NDA020118
SUPRANE	DESFLURANE	Baxter Healthcare Corporation	7f977eb6-c7c4-4dc5-ab3b-07414dbe5da5	2025-10-14	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020118 application number: NDA020118
SUPRANE	DESFLURANE	Baxter Healthcare Corporation	3fe3d468-d283-4dd0-a1a7-29291a9b2d0b	2025-10-14	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020118 application number: NDA020118
Suprane	DESFLURANE	Baxter Healthcare Corporation	efbb228b-7b38-4176-8bae-826103178c35	2025-10-14	Warnings, Adverse reactions	Exact identifier application applno (NDA): 020118 application number: NDA020118 ndc (product): 10019-644

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
CRS35BZ94Q	DESFLURANE	57041-67-5	DESFLURANE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
562366	desflurane 100 % Inhalation Solution	PSN	efbb228b-7b38-4176-8bae-826103178c35	17
208919	Suprane 100 % Inhalation Solution	PSN	efbb228b-7b38-4176-8bae-826103178c35	17
208919	desflurane 1000 MG/ML Inhalation Solution [Suprane]	SBD	efbb228b-7b38-4176-8bae-826103178c35	17
562366	desflurane 1000 MG/ML Inhalation Solution	SCD	efbb228b-7b38-4176-8bae-826103178c35	17
562366	desflurane 100 % Inhalation Solution	SY	efbb228b-7b38-4176-8bae-826103178c35	17
562366	desflurane 99 % Inhalation Solution	SY	efbb228b-7b38-4176-8bae-826103178c35	17
208919	Suprane 1 ML/ML Inhalation Solution	SY	efbb228b-7b38-4176-8bae-826103178c35	17
208919	Suprane 100 % Inhalation Solution	SY	efbb228b-7b38-4176-8bae-826103178c35	17

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
10019-644-24	10019064424	6 BOTTLE, GLASS in 1 CARTON (10019-644-24) > 240 mL in 1 BOTTLE, GLASS (10019-644-60)		1992-09-18	0000-00-00	No	No	Current
10019-644-34	10019064434	6 BOTTLE in 1 CARTON (10019-644-34) / 240 mL in 1 BOTTLE (10019-644-64)	6 bottle	1992-09-18	0000-00-00	No	No	Current
10019-644-60	10019064460	240 mL in 1 BOTTLE, GLASS	240 ml					Historical
10019-644-64	10019064464	240 mL in 1 BOTTLE	240 ml					Historical

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Suprane - Baxter Healthcare Corporation	Baxter Healthcare Corporation	2025-10-14	HUMAN PRESCRIPTION DRUG LABEL	17