ANAFRANIL

Product NDC
0406-9907
11-digit product format
004069907
Labeler code
0406
Product ID
0406-9907_07af3867-7f3e-4e1c-8100-ad276cb6185f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
clomipramine hydrochloride
Dosage form
CAPSULE
Route
ORAL
Labeler
SpecGx LLC
Application
NDA019906
Marketing category
NDA
Marketing start
1989-12-29
Substance
CLOMIPRAMINE HYDROCHLORIDE
Active strength
50 mg/1
Pharmacologic classes
Tricyclic Antidepressant [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N019906-001ANAFRANILCLOMIPRAMINE HYDROCHLORIDE25MGCAPSULE / ORALABRLD, RS1989-12-29
N019906-002ANAFRANILCLOMIPRAMINE HYDROCHLORIDE50MGCAPSULE / ORALABRLD1989-12-29
N019906-003ANAFRANILCLOMIPRAMINE HYDROCHLORIDE75MGCAPSULE / ORALABRLD1989-12-29

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
N019906-001AB
N019906-002AB
N019906-003AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-29caaa826d4ba7…
2026-08-18 06:07:402026-07N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-29caaa826d4ba7…
2026-08-18 06:07:402026-07N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-29caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-29011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-29011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-2931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-2931067a03dcf5…
2025-08-23 18:47 UTC2025-08N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-296a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-296a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-29fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-29fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-29b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-29b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-2903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-2903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-2903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-292680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-292680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-292680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-295bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-295bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-295bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-29d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-29d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-29d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-29d06236e962d9…
2024-10-29 15:01 UTC2024-10N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-29d06236e962d9…
2024-10-29 15:01 UTC2024-10N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-29d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-2979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-2979d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-2979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-29301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019906-002ANAFRANIL50MGCAPSULE / ORALABRLD1989-12-29301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019906-003ANAFRANIL75MGCAPSULE / ORALABRLD1989-12-29301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019906-001ANAFRANIL25MGCAPSULE / ORALABRLD, RS1989-12-291e350fbaab3a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N019906-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N019906-002AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N019906-003AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N019906-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019906-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N019906-003AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019906-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019906-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N019906-003AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N019906-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019906-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N019906-003AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019906-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019906-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N019906-003AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019906-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019906-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N019906-003AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019906-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019906-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N019906-003AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019906-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019906-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N019906-003AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019906-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019906-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N019906-003AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019906-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019906-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N019906-003AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N019906-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019906-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N019906-003AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019906-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019906-002AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N019906-003AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019906-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019906-002AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N019906-003AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N019906-001AB11e350fbaab3a…

Additional Listing Data#

Finished product
Yes
Brand name base
ANAFRANIL
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CLOMIPRAMINE HYDROCHLORIDE50 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2LXW0L6GWJInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 6 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
857297Internal RxNorm lookup
857299Internal RxNorm lookup
857301Internal RxNorm lookup
857303Internal RxNorm lookup
857305Internal RxNorm lookup
857307Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4074b555-7635-41a9-809d-fae3b3610059Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
06ad84c7-ef7f-2b11-27cb-22ae93f433b6Product name920240422

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0406-9907-03ANAFRANIL30 in 1 BOTTLECAPSULE3022

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0406-9907-03EA - Each0406-99076b5b21b8-263f-44f7-abff-4a4117374a1f12012-07-24

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0406-9907ANAFRANIL (CLOMIPRAMINE HYDROCHLORIDE) CAPSULE [SPECGX LLC]22Current NDC, Legacy NDC, 1 package rows20241204_4074b555-7635-41a9-809d-fae3b3610059.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ANAFRANILCLOMIPRAMINE HYDROCHLORIDESpecGx LLC4074b555-7635-41a9-809d-fae3b36100592024-11-26Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019906
application number: NDA019906
ndc (product): 0406-9907
CLOMIPRAMINE HYDROCHLORIDECLOMIPRAMINE HYDROCHLORIDESpecGx LLCd7cee3fa-d05c-4702-8f75-f446627bdb492024-11-26Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 019906
application number: NDA019906

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
857299Anafranil 25 MG Oral CapsulePSN4074b555-7635-41a9-809d-fae3b361005922
857303Anafranil 50 MG Oral CapsulePSN4074b555-7635-41a9-809d-fae3b361005922
857307Anafranil 75 MG Oral CapsulePSN4074b555-7635-41a9-809d-fae3b361005922
857297clomiPRAMINE HCl 25 MG Oral CapsulePSN4074b555-7635-41a9-809d-fae3b361005922
857301clomiPRAMINE HCl 50 MG Oral CapsulePSN4074b555-7635-41a9-809d-fae3b361005922
857305clomiPRAMINE HCl 75 MG Oral CapsulePSN4074b555-7635-41a9-809d-fae3b361005922
857299clomipramine hydrochloride 25 MG Oral Capsule [Anafranil]SBD4074b555-7635-41a9-809d-fae3b361005922
857303clomipramine hydrochloride 50 MG Oral Capsule [Anafranil]SBD4074b555-7635-41a9-809d-fae3b361005922
857307clomipramine hydrochloride 75 MG Oral Capsule [Anafranil]SBD4074b555-7635-41a9-809d-fae3b361005922
857297clomipramine hydrochloride 25 MG Oral CapsuleSCD4074b555-7635-41a9-809d-fae3b361005922
857301clomipramine hydrochloride 50 MG Oral CapsuleSCD4074b555-7635-41a9-809d-fae3b361005922
857305clomipramine hydrochloride 75 MG Oral CapsuleSCD4074b555-7635-41a9-809d-fae3b361005922
857299Anafranil 25 MG Oral CapsuleSY4074b555-7635-41a9-809d-fae3b361005922
857303Anafranil 50 MG Oral CapsuleSY4074b555-7635-41a9-809d-fae3b361005922
857307Anafranil 75 MG Oral CapsuleSY4074b555-7635-41a9-809d-fae3b361005922

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0406-9907-030040699070330 CAPSULE in 1 BOTTLE (0406-9907-03) 30 capsule1989-12-290000-00-00NoNoCurrent