Daptomycin

Product NDC
0409-0120
11-digit product format
004090120
Labeler code
0409
Product ID
0409-0120_70737bda-cf0c-42f1-89bc-d47e321d2218
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
DAPTOMYCIN
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Labeler
Hospira, Inc.
Application
NDA210282
Marketing category
NDA
Marketing start
2021-08-02
Substance
DAPTOMYCIN
Active strength
350 mg/7mL
Pharmacologic classes
Lipopeptide Antibacterial [EPC], Lipopeptides [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N210282-001DAPTOMYCINDAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21
N210282-002DAPTOMYCINDAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21

Orange Book patents#

Current patent rows page 1 of 1 · 4 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N210282-001103575352033-09-11U-3176Drug product2021-07-20
N210282-00196559462033-09-11U-3175Drug product2021-07-20
N210282-002103575352033-09-11U-3176Drug product2021-07-20
N210282-00296559462033-09-11U-3175Drug product2021-07-20

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 66 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-216a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-2103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-212680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-215bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21d06236e962d9…
2024-10-29 15:01 UTC2024-10N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-2179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-211e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-211e350fbaab3a…
2024-05-31 18:47 UTC2024-05N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-218072bd15b7f6…
2024-05-31 18:47 UTC2024-05N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-215c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-215c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-215d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-215d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-214b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-214b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21782e0a99824c…
2021-12-28 21:50 UTC2021-12N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-21782e0a99824c…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N210282-001DAPTOMYCIN350MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-216a51e52b5d6a…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N210282-002DAPTOMYCIN500MG/VIALPOWDER / INTRAVENOUSRLD, RS2021-06-216a51e52b5d6a…

Observed Orange Book patent history#

Patent history page 1 of 4 · 132 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N210282-001103575352033-09-11U-3176Drug product2021-07-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210282-00196559462033-09-11U-3175Drug product2021-07-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210282-002103575352033-09-11U-3176Drug product2021-07-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02N210282-00296559462033-09-11U-3175Drug product2021-07-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210282-001103575352033-09-11U-3176Drug product2021-07-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210282-00196559462033-09-11U-3175Drug product2021-07-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210282-002103575352033-09-11U-3176Drug product2021-07-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N210282-00296559462033-09-11U-3175Drug product2021-07-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08N210282-001103575352033-09-11U-3176Drug product2021-07-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210282-00196559462033-09-11U-3175Drug product2021-07-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210282-002103575352033-09-11U-3176Drug product2021-07-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08N210282-00296559462033-09-11U-3175Drug product2021-07-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210282-001103575352033-09-11U-3176Drug product2021-07-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210282-00196559462033-09-11U-3175Drug product2021-07-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210282-002103575352033-09-11U-3176Drug product2021-07-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N210282-00296559462033-09-11U-3175Drug product2021-07-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210282-001103575352033-09-11U-3176Drug product2021-07-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210282-00196559462033-09-11U-3175Drug product2021-07-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210282-002103575352033-09-11U-3176Drug product2021-07-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N210282-00296559462033-09-11U-3175Drug product2021-07-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210282-001103575352033-09-11U-3176Drug product2021-07-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210282-00196559462033-09-11U-3175Drug product2021-07-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210282-002103575352033-09-11U-3176Drug product2021-07-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N210282-00296559462033-09-11U-3175Drug product2021-07-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210282-001103575352033-09-11U-3176Drug product2021-07-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210282-00196559462033-09-11U-3175Drug product2021-07-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210282-002103575352033-09-11U-3176Drug product2021-07-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N210282-00296559462033-09-11U-3175Drug product2021-07-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210282-001103575352033-09-11U-3176Drug product2021-07-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210282-00196559462033-09-11U-3175Drug product2021-07-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210282-002103575352033-09-11U-3176Drug product2021-07-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N210282-00296559462033-09-11U-3175Drug product2021-07-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210282-001103575352033-09-11U-3176Drug product2021-07-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210282-00196559462033-09-11U-3175Drug product2021-07-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210282-002103575352033-09-11U-3176Drug product2021-07-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N210282-00296559462033-09-11U-3175Drug product2021-07-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N210282-001103575352033-09-11U-3176Drug product2021-07-20d06236e962d9…
2024-10-29 15:01 UTC2024-10N210282-00196559462033-09-11U-3175Drug product2021-07-20d06236e962d9…
2024-10-29 15:01 UTC2024-10N210282-002103575352033-09-11U-3176Drug product2021-07-20d06236e962d9…
2024-10-29 15:01 UTC2024-10N210282-00296559462033-09-11U-3175Drug product2021-07-20d06236e962d9…

Additional Listing Data#

Finished product
Yes
Brand name base
Daptomycin
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DAPTOMYCIN350 mg/7mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
NWQ5N31VKKInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
403920Internal RxNorm lookup
1996246Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1957b6ce-7382-4a7b-bf02-3595948d09c6Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
45ca3ac7-6ee8-4e99-92a6-dc0b401e151aProduct name120250724
223d8260-7a4e-4ebd-9635-845422d6a8adProduct name920240909
ca803a62-3799-476f-bbc6-024f77cb0320Product name420240207
cad85d83-8fb9-49f8-a5a6-a399af412964Product name120230922
8e59a5ed-f224-4156-b534-1ae4d0b6dfd7Product name120230721
e2db08c6-133f-4f4f-afb4-e90a2418d6f6Product name120230320
ea2c89ab-e8f8-425f-9693-c923fa1e1703Product name120220929
ce6d5c06-3ae0-18a6-d5b3-8cd3cc0f8906Product name720210625
f52be47f-7aa7-46c0-b1fa-50c18dd50206Product name120201029
11ed6f83-cdd2-4637-8379-b1a1d3ae3cdeProduct name120181101
86c45a79-b9f0-4476-a27c-6e10db098497Product name120180125
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0409-0120-01Daptomycin7 mL in 1 VIAL, SINGLE-DOSEINJECTION, POWDER, LYOPHILIZED,76
0409-0120-01Daptomycin1 in 1 CARTONINJECTION, POWDER, LYOPHILIZED,16

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0409-0120-01EA - Each0409-012042e38a1a-2297-4c57-8488-57f71f08712212021-09-07

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0409-0120DAPTOMYCIN INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [HOSPIRA, INC.]5Current NDC, Legacy NDC, 2 package rows20250417_1957b6ce-7382-4a7b-bf02-3595948d09c6.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DaptomycinDAPTOMYCINHospira, Inc.1957b6ce-7382-4a7b-bf02-3595948d09c62026-05-08Warnings, Adverse reactionsExact identifier
application applno (NDA): 210282
application number: NDA210282
ndc (product): 0409-0120

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1996246DAPTOmycin 350 MG InjectionPSN1957b6ce-7382-4a7b-bf02-3595948d09c66
403920DAPTOmycin 500 MG InjectionPSN1957b6ce-7382-4a7b-bf02-3595948d09c66
1996246daptomycin 350 MG InjectionSCD1957b6ce-7382-4a7b-bf02-3595948d09c66
403920daptomycin 500 MG InjectionSCD1957b6ce-7382-4a7b-bf02-3595948d09c66

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
0409-0120-01004090120011 VIAL, SINGLE-DOSE in 1 CARTON (0409-0120-01) / 7 mL in 1 VIAL, SINGLE-DOSE2021-08-020000-00-00NoNoCurrent