Labetalol Hydrochloride

Product NDC
0409-0125
11-digit product format
004090125
Labeler code
0409
Product ID
0409-0125_c1772ea4-65eb-4f27-8e33-3de06278acfe
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Labetalol Hydrochloride
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Hospira, Inc.
Application
ANDA075240
Marketing category
ANDA
Marketing start
2023-08-07
Substance
LABETALOL HYDROCHLORIDE
Active strength
5 mg/mL
Pharmacologic classes
Adrenergic beta-Antagonists [MoA], beta-Adrenergic Blocker [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A075240-001LABETALOL HYDROCHLORIDELABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A075240-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-2931067a03dcf5…
2025-08-23 18:47 UTC2025-08A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-296a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-2903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-292680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-295bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-2979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-291e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-298072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-295c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-295d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-294b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-2974a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-2987673890dc5c…
2021-03-12 10:30 UTC2021-03A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-295aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-298869cabd3fbd…
2020-11-12 02:37 UTC2020-11A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29c0c555d07b60…
2019-12-14 00:12 UTC2019-12A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-293f01610625f2…
2019-09-15 20:21 UTC2019-09A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29b00525d2431f…
2019-07-19 19:46 UTC2019-07A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-296a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-291c564ffb4f44…
2023-12-20 04:57 UTC2023-12A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-299b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-293f0d92c62455…
2023-05-13 08:27 UTC2023-05A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29053a50430f4f…
2023-01-26 05:58 UTC2023-01A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-293bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-293a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A075240-001LABETALOL HYDROCHLORIDE5MG/MLINJECTABLE / INJECTIONAPRS1999-11-29cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A075240-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A075240-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A075240-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A075240-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A075240-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A075240-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A075240-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A075240-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A075240-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A075240-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A075240-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A075240-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A075240-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A075240-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A075240-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A075240-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A075240-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A075240-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A075240-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A075240-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A075240-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A075240-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A075240-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A075240-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A075240-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A075240-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A075240-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A075240-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A075240-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A075240-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A075240-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A075240-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A075240-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A075240-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A075240-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A075240-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A075240-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A075240-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A075240-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A075240-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Labetalol Hydrochloride
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LABETALOL HYDROCHLORIDE5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1GEV3BAW9JInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
896771Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
abfc6b75-1ed5-41f1-0484-4597488237bcAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
cb89b86a-369e-4204-8910-ae797c503af3Product name120230706
baf61d8c-dcd3-e95d-db84-9bb0d0a2b77fProduct name220220311
759f1c41-9262-4238-8cee-33988631aaf4Product name520220217
3b2edbb4-6acf-4674-b1d9-22addd3dad21Product name120210527
d4880ace-a516-8c47-8dfd-73a4ba5887d7Product name220180830
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0409-0125-01Labetalol Hydrochloride20 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION2028
0409-0125-25Labetalol Hydrochloride25 in 1 TRAYINJECTION, SOLUTION2528

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0409-0125-01ML - Milliliter0409-01253c39fa22-c2da-4058-8d0f-dd0f853a5da412023-09-05
0409-0125-25ML - Milliliter0409-012598c0b555-eb7f-448e-ba91-1fae008bdadd12023-09-05

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
LABETALOL HYDROCHLORIDEACTIVE INGREDIENT1GEV3BAW9JLABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]13
LABETALOLACTIVE MOIETYR5H8897N95LABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]13
ANHYDROUS DEXTROSEINACTIVE INGREDIENT5SL0G7R0OKLABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]13
CITRIC ACID MONOHYDRATEINACTIVE INGREDIENT2968PHW8QPLABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]13
EDETATE DISODIUMINACTIVE INGREDIENT7FLD91C86KLABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]13
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TLABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]13
PROPYLPARABENINACTIVE INGREDIENTZ8IX2SC1OHLABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]13
SODIUM HYDROXIDEINACTIVE INGREDIENT55X04QC32ILABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0409-0125LABETALOL HYDROCHLORIDE INJECTION, SOLUTION [HOSPIRA, INC.]25Current NDC, 2 package rows20241210_abfc6b75-1ed5-41f1-0484-4597488237bc.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Labetalol HydrochlorideLABETALOL HYDROCHLORIDEHospira, Inc.abfc6b75-1ed5-41f1-0484-4597488237bc2026-07-13Warnings, Adverse reactionsExact identifier
application applno (ANDA): 075240
application number: ANDA075240
ndc (product): 0409-0125

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
896771labetalol HCl 5 MG/ML Injectable SolutionPSNabfc6b75-1ed5-41f1-0484-4597488237bc28
896771labetalol hydrochloride 5 MG/ML Injectable SolutionSCDabfc6b75-1ed5-41f1-0484-4597488237bc28

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
0409-0125-010040901250120 mL in 1 VIAL, MULTI-DOSE20 mlHistorical
0409-0125-250040901252525 VIAL, MULTI-DOSE in 1 TRAY (0409-0125-25) / 20 mL in 1 VIAL, MULTI-DOSE (0409-0125-01) 2023-08-07NoNoCurrent