Morphine sulfate

Product NDC
0409-2022
11-digit product format
004092022
Labeler code
0409
Product ID
0409-2022_6f2d5741-5543-4bea-8d1d-7e4889b634a0
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Morphine Sulfate
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Hospira, Inc.
Application
NDA202515
Marketing category
NDA
Marketing start
2025-04-21
Substance
MORPHINE SULFATE
Active strength
50 mg/mL
Pharmacologic classes
Full Opioid Agonists [MoA], Opioid Agonist [EPC]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 20 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage0409-2022-012ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage0409-2022-01a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage0409-2022-01cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage0409-2022-01cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage0409-2022-01302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage0409-2022-01ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage0409-2022-010efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage0409-2022-01ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage0409-2022-01367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage0409-2022-01557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 6 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N202515-001MORPHINE SULFATEMORPHINE SULFATE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2011-11-14
N202515-002MORPHINE SULFATEMORPHINE SULFATE4MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14
N202515-003MORPHINE SULFATEMORPHINE SULFATE8MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14
N202515-004MORPHINE SULFATEMORPHINE SULFATE10MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14
N202515-005MORPHINE SULFATEMORPHINE SULFATE15MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2011-11-14
N202515-006MORPHINE SULFATEMORPHINE SULFATE50MG/MLINJECTABLE / INJECTIONRLD, RS2021-04-29

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
N202515-001AP
N202515-002AP
N202515-003AP
N202515-004AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 7 · 244 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N202515-001MORPHINE SULFATE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2011-11-14caaa826d4ba7…
2026-08-18 06:07:402026-07N202515-002MORPHINE SULFATE4MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14caaa826d4ba7…
2026-08-18 06:07:402026-07N202515-003MORPHINE SULFATE8MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14caaa826d4ba7…
2026-08-18 06:07:402026-07N202515-004MORPHINE SULFATE10MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14caaa826d4ba7…
2026-08-18 06:07:402026-07N202515-005MORPHINE SULFATE15MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2011-11-14caaa826d4ba7…
2026-08-18 06:07:402026-07N202515-006MORPHINE SULFATE50MG/MLINJECTABLE / INJECTIONRLD, RS2021-04-29caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N202515-001MORPHINE SULFATE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2011-11-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202515-002MORPHINE SULFATE4MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202515-003MORPHINE SULFATE8MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202515-004MORPHINE SULFATE10MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202515-005MORPHINE SULFATE15MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2011-11-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202515-006MORPHINE SULFATE50MG/MLINJECTABLE / INJECTIONRLD, RS2021-04-29011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-001MORPHINE SULFATE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2011-11-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-002MORPHINE SULFATE4MG/MLINJECTABLE / INJECTIONAPRLD2011-11-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-003MORPHINE SULFATE8MG/MLINJECTABLE / INJECTIONAPRLD2011-11-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-004MORPHINE SULFATE10MG/MLINJECTABLE / INJECTIONAPRLD2011-11-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-005MORPHINE SULFATE15MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2011-11-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-006MORPHINE SULFATE50MG/MLINJECTABLE / INJECTIONRLD, RS2021-04-2931067a03dcf5…
2025-08-23 18:47 UTC2025-08N202515-001MORPHINE SULFATE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2011-11-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202515-002MORPHINE SULFATE4MG/MLINJECTABLE / INJECTIONAPRLD2011-11-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202515-003MORPHINE SULFATE8MG/MLINJECTABLE / INJECTIONAPRLD2011-11-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202515-004MORPHINE SULFATE10MG/MLINJECTABLE / INJECTIONAPRLD2011-11-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202515-005MORPHINE SULFATE15MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2011-11-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202515-006MORPHINE SULFATE50MG/MLINJECTABLE / INJECTIONRLD, RS2021-04-296a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-001MORPHINE SULFATE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2011-11-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-002MORPHINE SULFATE4MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-003MORPHINE SULFATE8MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-004MORPHINE SULFATE10MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-005MORPHINE SULFATE15MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2011-11-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-006MORPHINE SULFATE50MG/MLINJECTABLE / INJECTIONRLD, RS2021-04-29fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-001MORPHINE SULFATE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2011-11-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-002MORPHINE SULFATE4MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-003MORPHINE SULFATE8MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-004MORPHINE SULFATE10MG/MLINJECTABLE / INJECTIONAPRLD2011-11-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-005MORPHINE SULFATE15MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2011-11-14b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-006MORPHINE SULFATE50MG/MLINJECTABLE / INJECTIONRLD, RS2021-04-29b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202515-001MORPHINE SULFATE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2011-11-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202515-002MORPHINE SULFATE4MG/MLINJECTABLE / INJECTIONAPRLD2011-11-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202515-003MORPHINE SULFATE8MG/MLINJECTABLE / INJECTIONAPRLD2011-11-1403ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202515-004MORPHINE SULFATE10MG/MLINJECTABLE / INJECTIONAPRLD2011-11-1403ed91905a0d…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 144 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N202515-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07N202515-002AP1caaa826d4ba7…
2026-08-18 06:07:402026-07N202515-003AP1caaa826d4ba7…
2026-08-18 06:07:402026-07N202515-004AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N202515-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202515-002AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202515-003AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N202515-004AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-002AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-003AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N202515-004AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N202515-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202515-002AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202515-003AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N202515-004AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-002AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-003AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N202515-004AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-002AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-003AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N202515-004AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202515-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202515-002AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202515-003AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N202515-004AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202515-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202515-002AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202515-003AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N202515-004AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202515-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202515-002AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202515-003AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N202515-004AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202515-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202515-002AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202515-003AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N202515-004AP1d8e5a09893c0…

Additional Listing Data#

Finished product
Yes
Brand name base
Morphine sulfate
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
MORPHINE SULFATE50 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
X3P646A2J0Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1731537Internal RxNorm lookup
1731545Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ee8057d1-ed12-4e18-9efa-d83504abf612Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
89941d4c-522d-cee0-b273-43cfa7ef6d35Product name420250516
f15f9e76-db42-8a50-218a-5ef5affa58daProduct name420240216
944b0689-73f4-6a2f-c654-1180896353c0Product name420220210
67e166c6-23d4-4709-b77d-5ca6182dcae0Product name120180830
c573a64c-fe17-2eac-fbcb-788868b4ff6bProduct name920180619
7c1819cf-69a0-41dc-aeaa-a820729bc959Product name120170406
7a68fc31-10e5-df04-67e0-3a613a2d4d2eProduct name520161114
175682a8-c657-45a2-9dfb-c565306b03c8Product name120160112
b73dadd0-1b4a-4f88-956f-a2be216c8fadProduct name120151123
4c272b1c-87fc-ebc0-994d-ac28b1e0416eProduct name120140508
7a537f54-d322-5e54-a3a2-035d3e21c3c6Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0409-2022-01Morphine sulfate1 in 1 CARTONINJECTION, SOLUTION17
0409-2022-01Morphine sulfate50 mL in 1 VIAL, SINGLE-DOSEINJECTION, SOLUTION507

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0409-2022-01ML - Milliliter0409-2022919085b5-42e5-48d1-851c-3d5b81c802c112025-05-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0409-2022MORPHINE SULFATE INJECTION, SOLUTION MORPHINE SULFATE INJECTION, SOLUTION [HOSPIRA, INC.]5Current NDC, 2 package rows20250425_ee8057d1-ed12-4e18-9efa-d83504abf612.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Morphine SulfateMORPHINE SULFATEHospira, Inc.be420e8b-bcb0-49b5-bb4d-1df8b99598092025-12-31Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 202515
application number: NDA202515
Morphine SulfateMORPHINE SULFATEHospira, Inc.ee8057d1-ed12-4e18-9efa-d83504abf6122025-12-31Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 202515
application number: NDA202515
ndc (product): 0409-2022

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1731537morphine sulfate 1 GM in 20 ML InjectionPSNee8057d1-ed12-4e18-9efa-d83504abf6127
1731545morphine sulfate 2.5 GM in 50 ML InjectionPSNee8057d1-ed12-4e18-9efa-d83504abf6127
173153720 ML morphine sulfate 50 MG/ML InjectionSCDee8057d1-ed12-4e18-9efa-d83504abf6127
173154550 ML morphine sulfate 50 MG/ML InjectionSCDee8057d1-ed12-4e18-9efa-d83504abf6127
173153720 ML MS 50 MG/ML InjectionSYee8057d1-ed12-4e18-9efa-d83504abf6127
173154550 ML MS 50 MG/ML InjectionSYee8057d1-ed12-4e18-9efa-d83504abf6127
1731537morphine sulfate 1 GM per 20 ML InjectionSYee8057d1-ed12-4e18-9efa-d83504abf6127
1731545morphine sulfate 2.5 GM per 50 ML InjectionSYee8057d1-ed12-4e18-9efa-d83504abf6127

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
0409-2022-01004092022011 VIAL, SINGLE-DOSE in 1 CARTON (0409-2022-01) / 50 mL in 1 VIAL, SINGLE-DOSE2025-04-21NoNoCurrent