Ketamine Hydrochloride

Product NDC
0409-2053
11-digit product format
004092053
Labeler code
0409
Product ID
0409-2053_37921fa5-8ef5-4af7-bf99-3a9ab24fa752
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Ketamine Hydrochloride
Dosage form
INJECTION, SOLUTION, CONCENTRATE
Route
INTRAMUSCULAR; INTRAVENOUS
Labeler
Hospira, Inc.
Application
ANDA074549
Marketing category
ANDA
Marketing start
2004-11-30
Substance
KETAMINE HYDROCHLORIDE
Active strength
50 mg/mL
Pharmacologic classes
General Anesthesia [PE], General Anesthetic [EPC]
DEA schedule
CIII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A074549-001KETAMINE HYDROCHLORIDEKETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27
A074549-002KETAMINE HYDROCHLORIDEKETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A074549-001AP
A074549-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27caaa826d4ba7…
2026-08-18 06:07:402026-07A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27d06236e962d9…
2024-10-29 15:01 UTC2024-10A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-278072bd15b7f6…
2024-05-31 18:47 UTC2024-05A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-275c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-275d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-275d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-274b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-274b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-2774a2ff9319b5…
2019-12-13 00:20 UTC2019-12A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-2774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074549-001KETAMINE HYDROCHLORIDEEQ 50MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A074549-002KETAMINE HYDROCHLORIDEEQ 100MG BASE/MLINJECTABLE / INJECTIONAP1996-06-27bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A074549-001AP1caaa826d4ba7…
2026-08-18 06:07:402026-07A074549-002AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A074549-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A074549-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074549-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074549-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A074549-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A074549-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074549-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074549-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074549-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074549-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074549-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074549-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074549-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074549-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074549-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074549-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074549-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074549-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074549-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A074549-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074549-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074549-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074549-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074549-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074549-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074549-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074549-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A074549-002AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074549-001AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074549-002AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074549-001AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A074549-002AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074549-001AP14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A074549-002AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074549-001AP174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A074549-002AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074549-001AP1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A074549-002AP1bb7c543d1eb4…

Additional Listing Data#

Finished product
Yes
Brand name base
Ketamine Hydrochloride
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
KETAMINE HYDROCHLORIDE50 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
O18YUO0I83Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
238083Internal RxNorm lookup
238084Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
bb912318-2e22-4469-b0a2-774803ee1bb8Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
bb4bf50b-0475-bcb2-86ff-7b0cc2cc55bcProduct name220240223

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0409-2053-10Ketamine Hydrochloride10 in 1 BOXINJECTION, SOLUTION, CONCENTRATE1019
0409-2053-20Ketamine Hydrochloride10 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION, CONCENTRATE1019

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0409-2053-10ML - Milliliter0409-20531704d192-0e1d-433a-ab86-3a2342f5561612012-07-24
0409-2053-20ML - Milliliter0409-205348167349-a07a-4e38-81ad-dd4314c43e5112020-01-03

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0409-2053KETAMINE HYDROCHLORIDE INJECTION, SOLUTION, CONCENTRATE [HOSPIRA, INC.]19Current NDC, Legacy NDC, 2 package rows20240717_bb912318-2e22-4469-b0a2-774803ee1bb8.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
KETAMINE HYDROCHLORIDEKETAMINE HYDROCHLORIDEHenry Schein, Inc.dd8eff00-b92e-4f48-8b57-0464484d6ddf2026-07-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074549
application number: ANDA074549
Ketamine HydrochlorideKETAMINE HYDROCHLORIDEHospira, Inc.bb912318-2e22-4469-b0a2-774803ee1bb82026-05-12Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074549
application number: ANDA074549
ndc (product): 0409-2053
Ketamine HydrochlorideKETAMINE HYDROCHLORIDEMedical Purchasing Solutions, LLCea600f8a-857f-4e0e-e053-2995a90a017d2023-04-24Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074549
application number: ANDA074549

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
238084ketamine 50 MG/ML Injectable SolutionPSNdd8eff00-b92e-4f48-8b57-0464484d6ddf5
238084ketamine 50 MG/ML Injectable SolutionSCDdd8eff00-b92e-4f48-8b57-0464484d6ddf5
238084ketamine (as ketamine hydrochloride) 50 MG/ML Injectable SolutionSYdd8eff00-b92e-4f48-8b57-0464484d6ddf5
238084ketamine 50 MG/ML Injectable SolutionPSN94e75168-b271-4f7e-96d5-716eb9c32dfa1
238084ketamine 50 MG/ML Injectable SolutionSCD94e75168-b271-4f7e-96d5-716eb9c32dfa1
238084ketamine (as ketamine hydrochloride) 50 MG/ML Injectable SolutionSY94e75168-b271-4f7e-96d5-716eb9c32dfa1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0409-2053-100040920531010 VIAL, MULTI-DOSE in 1 BOX (0409-2053-10) / 10 mL in 1 VIAL, MULTI-DOSE (0409-2053-20) 2004-11-300000-00-00NoNoCurrent
0409-2053-200040920532010 mL in 1 VIAL, MULTI-DOSE10 mlHistorical