Vitamin K1

Product NDC
0409-9157
11-digit product format
004099157
Labeler code
0409
Product ID
0409-9157_42b6397b-1ec3-4182-95cf-e2dfe5c19a28
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
PHYTONADIONE
Dosage form
INJECTION, EMULSION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Labeler
Hospira, Inc.
Application
ANDA087954
Marketing category
ANDA
Marketing start
2005-06-22
Substance
PHYTONADIONE
Active strength
2 mg/mL
Pharmacologic classes
Increased Prothrombin Activity [PE], Reversed Anticoagulation Activity [PE], Vitamin K [CS], Vitamin K [EPC], Warfarin Reversal Agent [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A087954-001VITAMIN K1PHYTONADIONE1MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A087954-001BP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRS1983-07-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRS1983-07-2587673890dc5c…
2021-03-12 10:30 UTC2021-03A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRS1983-07-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRS1983-07-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRS1983-07-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRS1983-07-253f01610625f2…
2019-09-15 20:21 UTC2019-09A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRS1983-07-25b00525d2431f…
2019-07-19 19:46 UTC2019-07A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRS1983-07-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-253f0d92c62455…
2023-05-13 08:27 UTC2023-05A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25053a50430f4f…
2023-01-26 05:58 UTC2023-01A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087954-001VITAMIN K11MG/0.5MLINJECTABLE / INJECTIONBPRLD, RS1983-07-25e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A087954-001BP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A087954-001BP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087954-001BP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A087954-001BP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087954-001BP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087954-001BP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087954-001BP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087954-001BP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087954-001BP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087954-001BP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087954-001BP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087954-001BP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087954-001BP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087954-001BP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087954-001BP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087954-001BP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087954-001BP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087954-001BP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087954-001BP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087954-001BP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087954-001BP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087954-001BP187673890dc5c…
2021-03-12 10:30 UTC2021-03A087954-001BP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087954-001BP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087954-001BP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087954-001BP13f01610625f2…
2019-09-15 20:21 UTC2019-09A087954-001BP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A087954-001BP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087954-001BP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087954-001BP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087954-001BP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087954-001BP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087954-001BP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087954-001BP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087954-001BP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A087954-001BP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A087954-001BP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087954-001BP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087954-001BP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087954-001BP1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
Vitamin K1
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PHYTONADIONE2 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
A034SE7857Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
312424Internal RxNorm lookup
1670192Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e8808230-2c44-44c6-8cab-8f29b6b34051Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
16a2c1cd-ae95-d910-f03d-7e06b11dd243Product name520260202
653485de-0601-41e4-82db-7a60bb223e27Product name120251024
23fb3cda-2b50-f3d3-ebde-f542350bd77bProduct name420240828
cb89b86a-369e-4204-8910-ae797c503af3Product name120230706
081b54f0-4545-48b6-b854-03e1401f09eaProduct name120230112
d4880ace-a516-8c47-8dfd-73a4ba5887d7Product name220180830
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
aead65a2-216e-4ff8-a178-44aab77c24edProduct name120180531
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0409-9157-01Vitamin K15 in 1 CONTAINERINJECTION, EMULSION522
0409-9157-31Vitamin K10.5 mL in 1 AMPULEINJECTION, EMULSION0.522
0409-9157-50Vitamin K15 in 1 TRAYINJECTION, EMULSION522

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0409-9157-01ML - Milliliter0409-91574b6a3151-7faf-490f-a44d-2eb7b33591eb12012-07-24
0409-9157-25ML - Milliliter0409-9157d2e6c6cd-2a7f-47d3-b960-213e37d820a312014-11-05
0409-9157-31ML - Milliliter0409-915715ddf269-d1db-4562-9bf0-8a13044f9b8412019-08-06
0409-9157-50ML - Milliliter0409-9157780cd970-f468-4055-ab57-403f9bc5258812019-08-06

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0409-9157VITAMIN K1 (PHYTONADIONE) INJECTION, EMULSION [HOSPIRA, INC.]20Current NDC, Legacy NDC, 3 package rows20241207_e8808230-2c44-44c6-8cab-8f29b6b34051.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Vitamin K1PHYTONADIONEHospira, Inc.e8808230-2c44-44c6-8cab-8f29b6b340512026-08-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087954
application number: ANDA087954
ndc (product): 0409-9157
VITAMIN K1 PHYTONADIONEVITAMIN K1, PHYTONADIONEHF Acquisition Co LLC, DBA HealthFirstcfc0df9f-ee59-9e30-e053-2995a90ad4492026-06-11Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087954
application number: ANDA087954

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
312424phytonadione 1 MG in 0.5 ML InjectionPSNe8808230-2c44-44c6-8cab-8f29b6b3405122
1670192phytonadione 10 MG in 1 ML InjectionPSNe8808230-2c44-44c6-8cab-8f29b6b3405122
3124240.5 ML vitamin K1 2 MG/ML InjectionSCDe8808230-2c44-44c6-8cab-8f29b6b3405122
16701921 ML vitamin K1 10 MG/ML InjectionSCDe8808230-2c44-44c6-8cab-8f29b6b3405122
312424phytonadione 1 MG per 0.5 ML InjectionSYe8808230-2c44-44c6-8cab-8f29b6b3405122
1670192phytonadione 10 MG per 1 ML InjectionSYe8808230-2c44-44c6-8cab-8f29b6b3405122
1670192vitamin K 1 10 MG per 1 ML InjectionSYe8808230-2c44-44c6-8cab-8f29b6b3405122
312424phytonadione 1 MG in 0.5 ML InjectionPSNf922f301-f5ab-4db8-b6a6-364f95fff09c8
3124240.5 ML vitamin K1 2 MG/ML InjectionSCDf922f301-f5ab-4db8-b6a6-364f95fff09c8
312424phytonadione 1 MG per 0.5 ML InjectionSYf922f301-f5ab-4db8-b6a6-364f95fff09c8
312424phytonadione 1 MG in 0.5 ML InjectionPSNcfc0df9f-ee59-9e30-e053-2995a90ad4493
3124240.5 ML vitamin K1 2 MG/ML InjectionSCDcfc0df9f-ee59-9e30-e053-2995a90ad4493
312424phytonadione 1 MG per 0.5 ML InjectionSYcfc0df9f-ee59-9e30-e053-2995a90ad4493

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0409-9157-01004099157015 TRAY in 1 CONTAINER (0409-9157-01) / 5 AMPULE in 1 TRAY (0409-9157-50) / .5 mL in 1 AMPULE (0409-9157-31) 5 tray2005-06-220000-00-00NoNoCurrent
0409-9157-31004099157310.5 mL in 1 AMPULE0.5 mlHistorical
0409-9157-50004099157505 in 1 TRAYHistorical