Vitamin K1

Product NDC
0409-9158
Requested package NDC
0409-9158-01
11-digit product format
004099158
Labeler code
0409
Product ID
0409-9158_42b6397b-1ec3-4182-95cf-e2dfe5c19a28
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
PHYTONADIONE
Dosage form
INJECTION, EMULSION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Labeler
Hospira, Inc.
Application
ANDA087955
Marketing category
ANDA
Marketing start
2005-07-27
Substance
PHYTONADIONE
Active strength
10 mg/mL
Pharmacologic classes
Increased Prothrombin Activity [PE], Reversed Anticoagulation Activity [PE], Vitamin K [CS], Vitamin K [EPC], Warfarin Reversal Agent [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A087955-001VITAMIN K1PHYTONADIONE10MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A087955-001AB1

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRLD, RS1983-07-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRLD, RS1983-07-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRS1983-07-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRLD, RS1983-07-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRLD, RS1983-07-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRS1983-07-2587673890dc5c…
2021-03-12 10:30 UTC2021-03A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRS1983-07-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRS1983-07-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRS1983-07-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRS1983-07-253f01610625f2…
2019-09-15 20:21 UTC2019-09A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRS1983-07-25b00525d2431f…
2019-07-19 19:46 UTC2019-07A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONABRS1983-07-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-253f0d92c62455…
2023-05-13 08:27 UTC2023-05A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25053a50430f4f…
2023-01-26 05:58 UTC2023-01A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A087955-001VITAMIN K110MG/MLINJECTABLE / INJECTIONAB1RLD, RS1983-07-25cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A087955-001AB11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A087955-001AB1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A087955-001AB116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A087955-001AB11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A087955-001AB11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A087955-001AB1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A087955-001AB112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A087955-001AB115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A087955-001AB11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A087955-001AB11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A087955-001AB1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A087955-001AB11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A087955-001AB111e350fbaab3a…
2024-05-31 18:47 UTC2024-05A087955-001AB118072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A087955-001AB115c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A087955-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A087955-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A087955-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A087955-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A087955-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A087955-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A087955-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A087955-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A087955-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A087955-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A087955-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A087955-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A087955-001AB116a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A087955-001AB111c564ffb4f44…
2023-12-20 04:57 UTC2023-12A087955-001AB11ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A087955-001AB11a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A087955-001AB119b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A087955-001AB11a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A087955-001AB113f0d92c62455…
2023-05-13 08:27 UTC2023-05A087955-001AB11053a50430f4f…
2023-01-26 05:58 UTC2023-01A087955-001AB113bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A087955-001AB113a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A087955-001AB11f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A087955-001AB11e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A087955-001AB11cb3db0bc1861…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Vitamin K1PHYTONADIONEHospira, Inc.e8808230-2c44-44c6-8cab-8f29b6b340512026-05-25Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087955
application number: ANDA087955
ndc (package): 0409-9158-01
ndc (product): 0409-9158
ndc11 (package): 00409915801
VITAMIN K1 - PHYTONADIONEVITAMIN K1 - PHYTONADIONEHF Acquisition Co LLC, DBA HealthFirstc204c720-88d3-a6d6-e053-2a95a90a3de52024-01-30Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 087955
application number: ANDA087955

Additional Listing Data#

Finished product
Yes
Brand name base
Vitamin K1
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
PHYTONADIONE10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
A034SE7857Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
312424Internal RxNorm lookup
1670192Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
e8808230-2c44-44c6-8cab-8f29b6b34051Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
16a2c1cd-ae95-d910-f03d-7e06b11dd243Product name520260202
653485de-0601-41e4-82db-7a60bb223e27Product name120251024
23fb3cda-2b50-f3d3-ebde-f542350bd77bProduct name420240828
cb89b86a-369e-4204-8910-ae797c503af3Product name120230706
081b54f0-4545-48b6-b854-03e1401f09eaProduct name120230112
d4880ace-a516-8c47-8dfd-73a4ba5887d7Product name220180830
7cda52fc-125f-421c-8fea-bc1974370c49Product name220180703
aead65a2-216e-4ff8-a178-44aab77c24edProduct name120180531
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324
9869efd7-d6dd-0665-5b67-53adbe6ef15eProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0409-9158-01Vitamin K15 in 1 CONTAINERINJECTION, EMULSION522
0409-9158-11Vitamin K11 mL in 1 AMPULEINJECTION, EMULSION122
0409-9158-25Vitamin K15 in 1 CONTAINERINJECTION, EMULSION522
0409-9158-31Vitamin K11 mL in 1 AMPULEINJECTION, EMULSION122
0409-9158-50Vitamin K15 in 1 TRAYINJECTION, EMULSION522
0409-9158-55Vitamin K15 in 1 TRAYINJECTION, EMULSION522

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0409-9158-01ML - Milliliter0409-91588fb330d1-d404-4a78-acfd-5df697a9e0ed12012-07-24
0409-9158-11ML - Milliliter0409-91580146bc02-99f6-4ebe-a841-7efdf09f67dd12021-02-05
0409-9158-25ML - Milliliter0409-91589d751c42-e63b-4531-8311-b1ca698b07c912014-06-03
0409-9158-31ML - Milliliter0409-91589210626c-ca6b-4eb6-8838-e7aaf567167a12019-08-06
0409-9158-50ML - Milliliter0409-9158d79e15d2-250f-4ed6-a41f-eaeb180b849312019-08-06
0409-9158-55ML - Milliliter0409-9158ecccb6dd-8e29-4af1-88ae-a857682144b112021-02-05

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0409-9158VITAMIN K1 (PHYTONADIONE) INJECTION, EMULSION [HOSPIRA, INC.]20Current NDC, Legacy NDC, 6 package rows20241207_e8808230-2c44-44c6-8cab-8f29b6b34051.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
312424phytonadione 1 MG in 0.5 ML InjectionPSNe8808230-2c44-44c6-8cab-8f29b6b3405122
1670192phytonadione 10 MG in 1 ML InjectionPSNe8808230-2c44-44c6-8cab-8f29b6b3405122
3124240.5 ML vitamin K1 2 MG/ML InjectionSCDe8808230-2c44-44c6-8cab-8f29b6b3405122
16701921 ML vitamin K1 10 MG/ML InjectionSCDe8808230-2c44-44c6-8cab-8f29b6b3405122
312424phytonadione 1 MG per 0.5 ML InjectionSYe8808230-2c44-44c6-8cab-8f29b6b3405122
1670192phytonadione 10 MG per 1 ML InjectionSYe8808230-2c44-44c6-8cab-8f29b6b3405122
1670192vitamin K 1 10 MG per 1 ML InjectionSYe8808230-2c44-44c6-8cab-8f29b6b3405122
1670192phytonadione 10 MG in 1 ML InjectionPSN4a203fc7-cd33-4e79-b835-d3b14d2a7f9d6
16701921 ML vitamin K1 10 MG/ML InjectionSCD4a203fc7-cd33-4e79-b835-d3b14d2a7f9d6
1670192phytonadione 10 MG per 1 ML InjectionSY4a203fc7-cd33-4e79-b835-d3b14d2a7f9d6
1670192vitamin K 1 10 MG per 1 ML InjectionSY4a203fc7-cd33-4e79-b835-d3b14d2a7f9d6
1670192phytonadione 10 MG in 1 ML InjectionPSNc204c720-88d3-a6d6-e053-2a95a90a3de53
16701921 ML vitamin K1 10 MG/ML InjectionSCDc204c720-88d3-a6d6-e053-2a95a90a3de53
1670192phytonadione 10 MG per 1 ML InjectionSYc204c720-88d3-a6d6-e053-2a95a90a3de53
1670192vitamin K 1 10 MG per 1 ML InjectionSYc204c720-88d3-a6d6-e053-2a95a90a3de53

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0409-9158-01004099158015 TRAY in 1 CONTAINER (0409-9158-01) / 5 AMPULE in 1 TRAY (0409-9158-50) / 1 mL in 1 AMPULE (0409-9158-31) 5 tray2005-07-270000-00-00NoNoCurrent