Tiopronin

Product NDC
0480-7824
11-digit product format
004807824
Labeler code
0480
Product ID
0480-7824_53891a64-8014-4b0b-9f13-cfc3d90166b2
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Tiopronin
Dosage form
TABLET, DELAYED RELEASE
Route
ORAL
Labeler
Teva Pharmaceuticals, Inc.
Application
ANDA216456
Marketing category
ANDA
Marketing start
2024-10-08
Substance
TIOPRONIN
Active strength
300 mg/1
Pharmacologic classes
Cystine Disulfide Reduction [MoA], N-substituted Glycines [CS], Reducing and Complexing Thiol [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A216456-001TIOPRONINTIOPRONIN100MGTABLET, DELAYED RELEASE / ORALAB2024-07-22
A216456-002TIOPRONINTIOPRONIN300MGTABLET, DELAYED RELEASE / ORALAB2024-07-22

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A216456-001AB
A216456-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06A216456-001TIOPRONIN100MGTABLET, DELAYED RELEASE / ORALAB2024-07-22a50c72e98297…
2026-08-01 22:54:322026-06A216456-002TIOPRONIN300MGTABLET, DELAYED RELEASE / ORALAB2024-07-22a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-01 22:54:322026-06A216456-001AB1a50c72e98297…
2026-08-01 22:54:322026-06A216456-002AB1a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TioproninTIOPRONINTeva Pharmaceuticals, Inc.749257d9-a519-4b10-9058-7fe3f301cdd22024-06-28Warnings, Adverse reactionsExact identifier
application applno (ANDA): 216456
application number: ANDA216456
ndc (product): 0480-7824

Additional Listing Data#

Finished product
Yes
Brand name base
Tiopronin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TIOPRONIN300 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
C5W04GO61SInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2178075Internal RxNorm lookup
2178079Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
749257d9-a519-4b10-9058-7fe3f301cdd2Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
19fd197c-a0a2-47ec-a473-bf965abd1795Product name220250429
a6c2b4b8-5194-92f1-e438-706fc5c2e8b4Product name320230303

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0480-7824-98Tiopronin90 in 1 BOTTLETABLET, DELAYED RELEASE904

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0480-7824-98EA - Each0480-7824155463c6-c912-4605-969e-1106a4b739f412024-11-05

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0480-7824TIOPRONIN TABLET, DELAYED RELEASE [TEVA PHARMACEUTICALS, INC.]4Current NDC, 1 package rows20241011_749257d9-a519-4b10-9058-7fe3f301cdd2.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2178075tiopronin 100 MG Delayed Release Oral TabletPSN749257d9-a519-4b10-9058-7fe3f301cdd24
2178079tiopronin 300 MG Delayed Release Oral TabletPSN749257d9-a519-4b10-9058-7fe3f301cdd24
2178075tiopronin 100 MG Delayed Release Oral TabletSCD749257d9-a519-4b10-9058-7fe3f301cdd24
2178079tiopronin 300 MG Delayed Release Oral TabletSCD749257d9-a519-4b10-9058-7fe3f301cdd24

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
0480-7824-980048078249890 TABLET, DELAYED RELEASE in 1 BOTTLE (0480-7824-98) 2024-10-08NoNoCurrent