memantine hydrochloride

Product NDC
0591-3900
11-digit product format
005913900
Labeler code
0591
Product ID
0591-3900_985e1190-b8a0-4775-9a20-ad1924b14fb2
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
memantine hydrochloride
Dosage form
KIT
Route
ORAL
Labeler
Actavis Pharma, Inc.
Application
NDA021487
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
2015-04-01
Marketing end
2028-08-31
NDC exclude flag
No
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021487-001NAMENDAMEMANTINE HYDROCHLORIDE5MGTABLET / ORALRLD2003-10-16
N021487-002NAMENDAMEMANTINE HYDROCHLORIDE10MGTABLET / ORALRLD2003-10-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N021487-001NAMENDA5MGTABLET / ORALRLD2003-10-16caaa826d4ba7…
2026-08-18 06:07:402026-07N021487-002NAMENDA10MGTABLET / ORALRLD2003-10-16caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-1631067a03dcf5…
2025-08-23 18:47 UTC2025-08N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-166a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-1603ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-1603ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-162680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-162680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-165bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-165bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16d06236e962d9…
2024-10-29 15:01 UTC2024-10N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-1679d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-1679d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-161e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-161e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-168072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-168072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-165c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-165c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-165d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-165d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-164b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-164b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-1674a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-1674a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021487-001NAMENDA5MGTABLET / ORALABRLD2003-10-16bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021487-002NAMENDA10MGTABLET / ORALABRLD, RS2003-10-16bb7c543d1eb4…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 80 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021487-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021487-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021487-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021487-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021487-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021487-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021487-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021487-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021487-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021487-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021487-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021487-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021487-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021487-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021487-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021487-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021487-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021487-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021487-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N021487-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021487-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021487-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021487-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021487-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021487-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021487-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021487-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021487-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021487-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021487-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021487-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021487-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021487-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021487-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021487-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021487-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021487-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021487-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021487-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12N021487-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
memantine hydrochloride

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
JY0WD0UA60Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 3 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
996561Internal RxNorm lookup
996571Internal RxNorm lookup
996572Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
72973b46-f307-4a9e-8fb1-ad2cbccfd736Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
94db636e-a074-45fd-8e8d-331920a99436Product name420250103
941773f8-a40e-0684-da08-ff9a143e6368Product name720231219
5b597f00-4538-4686-aa4e-3c60ed3788c8Product name220210511
1836e79a-a4d1-4087-2f2e-f878e8a1fef2Product name920151209

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0591-3900-87memantine hydrochloride1 in 1 BLISTER PACKKIT110
0591-3900-87memantine hydrochloride1 in 1 CARTONKIT110

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0591-3900-87EA - Each0591-3900c1294d08-4c32-4f08-9dc9-afba8d28592c12015-08-04

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
MEMANTINE HYDROCHLORIDEACTIVE INGREDIENTJY0WD0UA60MEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
memantineACTIVE MOIETYW8O17SJF3TMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
cellulose, microcrystallineINACTIVE INGREDIENTOP1R32D61UMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
citric acid monohydrateINACTIVE INGREDIENT2968PHW8QPMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
croscarmellose sodiumINACTIVE INGREDIENTM28OL1HH48MEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
FD&C blue No. 2INACTIVE INGREDIENTL06K8R7DQKMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
FD&C YELLOW NO. 6INACTIVE INGREDIENTH77VEI93A8MEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
ferrosoferric oxideINACTIVE INGREDIENTXM0M87F357MEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
glycerinINACTIVE INGREDIENTPDC6A3C0OXMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
hypromellosesINACTIVE INGREDIENT3NXW29V3WOMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
magnesium stearateINACTIVE INGREDIENT70097M6I30MEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
methylparabenINACTIVE INGREDIENTA2I8C7HI9TMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
polyethylene glycol 400INACTIVE INGREDIENTB697894SGQMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
propylene glycolINACTIVE INGREDIENT6DC9Q167V3MEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
propylparabenINACTIVE INGREDIENTZ8IX2SC1OHMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
silicon dioxideINACTIVE INGREDIENTETJ7Z6XBU4MEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
sodium citrateINACTIVE INGREDIENT1Q73Q2JULRMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
sorbitolINACTIVE INGREDIENT506T60A25RMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
talcINACTIVE INGREDIENT7SEV7J4R1UMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1
titanium dioxideINACTIVE INGREDIENT15FIX9V2JPMEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE SOLUTION MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0591-3900MEMANTINE HYDROCHLORIDE TABLET MEMANTINE HYDROCHLORIDE KIT [ACTAVIS PHARMA, INC.]10Current NDC, Legacy NDC, 2 package rows20240509_72973b46-f307-4a9e-8fb1-ad2cbccfd736.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
memantine hydrochlorideMEMANTINE HYDROCHLORIDECardinal Health 107, LLCe5754973-e73b-4a25-abb4-80f91880f0182026-06-05Warnings, Adverse reactionsExact identifier
application applno (NDA): 021487
application number: NDA021487
memantine hydrochlorideMEMANTINE HYDROCHLORIDEActavis Pharma, Inc.72973b46-f307-4a9e-8fb1-ad2cbccfd7362018-11-01Warnings, Adverse reactionsExact identifier
application applno (NDA): 021487
application number: NDA021487
ndc (product): 0591-3900
memantine hydrochlorideMEMANTINE HYDROCHLORIDEAphena Pharma Solutions - Tennessee, LLCc8f5c20b-4573-44c5-89fc-4da11b2e1fe12017-11-30Warnings, Adverse reactionsExact identifier
application applno (NDA): 021487
application number: NDA021487

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
996572{21 (memantine hydrochloride 10 MG Oral Tablet) / 28 (memantine hydrochloride 5 MG Oral Tablet) } PackGPCK72973b46-f307-4a9e-8fb1-ad2cbccfd73610
996561memantine HCl 10 MG Oral TabletPSN72973b46-f307-4a9e-8fb1-ad2cbccfd73610
996572memantine HCl 5 MG (28) / 10 MG (21) Tablet Titration PackPSN72973b46-f307-4a9e-8fb1-ad2cbccfd73610
996571memantine HCl 5 MG Oral TabletPSN72973b46-f307-4a9e-8fb1-ad2cbccfd73610
996561memantine hydrochloride 10 MG Oral TabletSCD72973b46-f307-4a9e-8fb1-ad2cbccfd73610
996571memantine hydrochloride 5 MG Oral TabletSCD72973b46-f307-4a9e-8fb1-ad2cbccfd73610
996572memantine HCl 5 MG (28) / 10 MG (21) Tablet Titration PackSY72973b46-f307-4a9e-8fb1-ad2cbccfd73610

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0591-3900-87005913900871 BLISTER PACK in 1 CARTON (0591-3900-87) / 1 KIT in 1 BLISTER PACK1 blister pack2015-04-012028-08-31NoNoCurrent