Hydromorphone Hydrochloride

Product NDC
0641-6151
11-digit product format
006416151
Labeler code
0641
Product ID
0641-6151_4c244852-0374-445f-8419-72e8ec359faa
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Hydromorphone Hydrochloride
Dosage form
INJECTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Labeler
Hikma Pharmaceuticals USA Inc.
Application
ANDA202159
Marketing category
ANDA
Marketing start
2018-07-01
Substance
HYDROMORPHONE HYDROCHLORIDE
Active strength
2 mg/mL
Pharmacologic classes
Full Opioid Agonists [MoA], Opioid Agonist [EPC]
DEA schedule
CII
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A202159-001HYDROMORPHONE HYDROCHLORIDEHYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A202159-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-275d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-274b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-2774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-2787673890dc5c…
2021-03-12 10:30 UTC2021-03A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-275aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-278869cabd3fbd…
2020-11-12 02:37 UTC2020-11A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27c0c555d07b60…
2019-12-14 00:12 UTC2019-12A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-273f01610625f2…
2019-09-15 20:21 UTC2019-09A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27b00525d2431f…
2019-07-19 19:46 UTC2019-07A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-276a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-271c564ffb4f44…
2023-12-20 04:57 UTC2023-12A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-279b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-273f0d92c62455…
2023-05-13 08:27 UTC2023-05A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27053a50430f4f…
2023-01-26 05:58 UTC2023-01A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-273bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-273a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A202159-001HYDROMORPHONE HYDROCHLORIDE2MG/MLINJECTABLE / INJECTIONAP2018-04-27cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A202159-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202159-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A202159-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202159-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202159-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202159-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202159-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202159-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202159-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202159-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202159-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202159-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202159-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202159-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202159-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202159-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202159-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202159-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202159-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202159-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202159-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A202159-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A202159-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A202159-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A202159-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A202159-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A202159-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A202159-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A202159-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A202159-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A202159-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A202159-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A202159-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A202159-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A202159-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A202159-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A202159-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A202159-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A202159-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A202159-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Hydromorphone Hydrochloride
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
HYDROMORPHONE HYDROCHLORIDE2 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
L960UP2KRWInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1724276Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
67e79859-4efc-4ea7-8211-cadf746bc864Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
c92985da-a658-b186-e763-2287eda87a86Product name320250221
96c475b3-58c7-b955-d715-0111804a3e50Product name520210512
1dd54659-b775-4fa8-a858-7f0e521fbadcProduct name420200925
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0641-6151-01Hydromorphone Hydrochloride1 mL in 1 VIAL, SINGLE-DOSEINJECTION18
0641-6151-25Hydromorphone Hydrochloride25 in 1 CARTONINJECTION258

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0641-6151-01ML - Milliliter0641-6151ba58df98-c828-4598-a032-628a6bbe30a512018-11-06
0641-6151-25ML - Milliliter0641-6151a9979b93-043b-4952-bb3b-e7b682b9308b12018-11-06

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0641-6151HYDROMORPHONE HYDROCHLORIDE INJECTION [HIKMA PHARMACEUTICALS USA INC.]8Current NDC, Legacy NDC, 2 package rows20240410_67e79859-4efc-4ea7-8211-cadf746bc864.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Hydromorphone HydrochlorideHYDROMORPHONE HYDROCHLORIDEHikma Pharmaceuticals USA Inc.67e79859-4efc-4ea7-8211-cadf746bc8642024-04-09Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202159
application number: ANDA202159
ndc (product): 0641-6151

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1724276HYDROmorphone HCl 2 MG in 1 ML InjectionPSN67e79859-4efc-4ea7-8211-cadf746bc8648
17242761 ML hydromorphone hydrochloride 2 MG/ML InjectionSCD67e79859-4efc-4ea7-8211-cadf746bc8648
1724276hydromorphone HCl 2 MG per 1 ML InjectionSY67e79859-4efc-4ea7-8211-cadf746bc8648

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0641-6151-01006416151011 mL in 1 VIAL, SINGLE-DOSE1 mlHistorical
0641-6151-250064161512525 VIAL, SINGLE-DOSE in 1 CARTON (0641-6151-25) / 1 mL in 1 VIAL, SINGLE-DOSE (0641-6151-01) 2018-07-010000-00-00NoNoCurrent