Ephedrine Sulfate

Product NDC
0641-6236
11-digit product format
006416236
Labeler code
0641
Product ID
0641-6236_2d36e5ea-35a6-467b-860c-2b1b136bb0f8
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Ephedrine Sulfate
Dosage form
INJECTION
Route
INTRAVENOUS
Labeler
Hikma Pharmaceuticals USA Inc.
Application
ANDA217721
Marketing category
ANDA
Marketing start
2024-12-20
Substance
EPHEDRINE SULFATE
Active strength
5 mg/mL
Pharmacologic classes
Adrenergic alpha-Agonists [MoA], Adrenergic beta-Agonists [MoA], Increased Norepinephrine Activity [PE], Norepinephrine Releasing Agent [EPC], alpha-Adrenergic Agonist [EPC], beta-Adrenergic Agonist [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217721-001EPHEDRINE SULFATEEPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP32024-10-11

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217721-001AP3

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP32024-10-11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP32024-10-1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP32024-10-116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-10-11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-10-11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-10-1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-10-112680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP2024-10-11d8e5a09893c0…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217721-001EPHEDRINE SULFATE25MG/5ML (5MG/ML)SOLUTION / INTRAVENOUSAP32024-10-11a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A217721-001AP31011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217721-001AP3131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217721-001AP316a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217721-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217721-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217721-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217721-001AP12680178bc6a6…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217721-001AP1d8e5a09893c0…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217721-001AP31a50c72e98297…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217721-001CGT2025-06-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08A217721-001CGT2025-06-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217721-001CGT2025-06-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217721-001CGT2025-06-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217721-001CGT2025-06-1803ed91905a0d…

Additional Listing Data#

Finished product
Yes
Brand name base
Ephedrine Sulfate
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
EPHEDRINE SULFATE5 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
U6X61U5ZEGInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
2586841Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
24787cb1-23e8-4baa-9838-a31a466b8c79Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
d1bd959e-e326-44fb-b8ca-8c56a84a2a3dProduct name220251211
f1d178e1-1663-4c63-ae37-62a1b322fba4Product name220251106
f606d3ac-dd63-4b29-bea0-db23753b8ddcProduct name120220118
30254138-2d98-4aa2-8e07-ae82e8b0a389Product name320171103
fee762de-ffd9-404d-8bc6-8c0c208e758dProduct name120170426

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0641-6236-10Ephedrine Sulfate10 in 1 CARTONINJECTION104
0641-6236-10Ephedrine Sulfate5 mL in 1 SYRINGE, PLASTICINJECTION54

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0641-6236-10ML - Milliliter0641-6236d59d6c33-5453-4d3d-b787-f628a878861e12025-01-14

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0641-6236EPHEDRINE SULFATE INJECTION [HIKMA PHARMACEUTICALS USA INC.]4Current NDC, 2 package rows20241222_24787cb1-23e8-4baa-9838-a31a466b8c79.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Ephedrine SulfateEPHEDRINE SULFATEHikma Pharmaceuticals USA Inc.24787cb1-23e8-4baa-9838-a31a466b8c792024-12-21Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217721
application number: ANDA217721
ndc (product): 0641-6236

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
2586841ePHEDrine sulfate 25 MG in 5 ML Prefilled SyringePSN24787cb1-23e8-4baa-9838-a31a466b8c794
25868415 ML ephedrine sulfate 5 MG/ML Prefilled SyringeSCD24787cb1-23e8-4baa-9838-a31a466b8c794
2586841ephedrine sulfate 25 MG (equivalent to 19 MG ephedrine) per 5 ML Prefilled SyringeSY24787cb1-23e8-4baa-9838-a31a466b8c794

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
0641-6236-100064162361010 SYRINGE, PLASTIC in 1 CARTON (0641-6236-10) / 5 mL in 1 SYRINGE, PLASTIC2024-12-20NoNoCurrent