Digoxin

Product NDC
0781-3059
11-digit product format
007813059
Labeler code
0781
Product ID
0781-3059_62ffbb27-b026-4fb2-b2a1-5c170036b8cf
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Digoxin
Dosage form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS; PARENTERAL
Labeler
Sandoz Inc
Application
ANDA040481
Marketing category
ANDA
Marketing start
2003-08-21
Substance
DIGOXIN
Active strength
250 ug/mL
Pharmacologic classes
Cardiac Glycoside [EPC], Cardiac Glycosides [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A040481-001DIGOXINDIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A040481-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-2131067a03dcf5…
2025-08-23 18:47 UTC2025-08A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-216a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-2103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-212680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-215bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-2179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-211e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-218072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-215c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-215d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-214b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-2174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-2187673890dc5c…
2021-03-12 10:30 UTC2021-03A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-215aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-218869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-213f01610625f2…
2019-09-15 20:21 UTC2019-09A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21b00525d2431f…
2019-07-19 19:46 UTC2019-07A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-216a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-211c564ffb4f44…
2023-12-20 04:57 UTC2023-12A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-219b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-213f0d92c62455…
2023-05-13 08:27 UTC2023-05A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21053a50430f4f…
2023-01-26 05:58 UTC2023-01A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-213bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-213a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040481-001DIGOXIN0.25MG/MLINJECTABLE / INJECTIONAP2003-08-21e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A040481-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A040481-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A040481-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A040481-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A040481-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A040481-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A040481-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A040481-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A040481-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A040481-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A040481-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A040481-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A040481-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A040481-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A040481-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A040481-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A040481-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A040481-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A040481-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A040481-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A040481-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A040481-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A040481-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A040481-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A040481-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A040481-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A040481-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A040481-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A040481-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A040481-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A040481-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A040481-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A040481-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A040481-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A040481-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A040481-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A040481-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A040481-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A040481-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A040481-001AP1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
Digoxin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DIGOXIN250 ug/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
73K4184T59Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
104208Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
58f45aba-ff6f-43cc-bb88-be40a9f7bedaAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
e2db08c6-133f-4f4f-afb4-e90a2418d6f6Product name120230320
20d84de3-cb46-44c4-9211-63e833fa2688Product name220221214
4d74103a-bb9b-9034-fbc8-dac635e6e729Product name320221117
ce6d5c06-3ae0-18a6-d5b3-8cd3cc0f8906Product name720210625
f52be47f-7aa7-46c0-b1fa-50c18dd50206Product name120201029
11ed6f83-cdd2-4637-8379-b1a1d3ae3cdeProduct name120181101
86c45a79-b9f0-4476-a27c-6e10db098497Product name120180125
d5e51f11-ad28-caa4-4b49-4143974782adProduct name120150831
5c3aa978-6f46-c7ca-2a83-b57385976beeProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0781-3059-72Digoxin2 mL in 1 AMPULEINJECTION, SOLUTION228
0781-3059-95Digoxin10 in 1 CARTONINJECTION, SOLUTION1028

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0781-3059-72ML - Milliliter0781-3059cd3c38ad-f9b0-4abc-af83-1bbde869cb1e12015-04-03
0781-3059-95ML - Milliliter0781-3059fa7386a2-12d0-4b52-a1d2-97cbe88223c112012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
DIGOXINACTIVE INGREDIENT73K4184T59DIGOXIN INJECTION, SOLUTION [SANDOZ INC]16
DIGOXINACTIVE MOIETY73K4184T59DIGOXIN INJECTION, SOLUTION [SANDOZ INC]16
ALCOHOLINACTIVE INGREDIENT3K9958V90MDIGOXIN INJECTION, SOLUTION [SANDOZ INC]16
ANHYDROUS CITRIC ACIDINACTIVE INGREDIENTXF417D3PSLDIGOXIN INJECTION, SOLUTION [SANDOZ INC]16
PROPYLENE GLYCOLINACTIVE INGREDIENT6DC9Q167V3DIGOXIN INJECTION, SOLUTION [SANDOZ INC]16
SODIUM PHOSPHATE, DIBASICINACTIVE INGREDIENTGR686LBA74DIGOXIN INJECTION, SOLUTION [SANDOZ INC]16

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0781-3059DIGOXIN INJECTION, SOLUTION [SANDOZ INC]27Current NDC, Legacy NDC, 2 package rows20241020_58f45aba-ff6f-43cc-bb88-be40a9f7beda.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DigoxinDIGOXINSandoz Inc58f45aba-ff6f-43cc-bb88-be40a9f7beda2025-12-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040481
application number: ANDA040481
ndc (product): 0781-3059
DigoxinDIGOXINMedical Purchasing Solutions, LLC28f2c2cd-e58c-aea2-e063-6394a90a73e72024-12-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 040481
application number: ANDA040481

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
104208digoxin 500 MCG in 2 ML InjectionPSN58f45aba-ff6f-43cc-bb88-be40a9f7beda28
1042082 ML digoxin 0.25 MG/ML InjectionSCD58f45aba-ff6f-43cc-bb88-be40a9f7beda28
104208digoxin 500 MCG per 2 ML InjectionSY58f45aba-ff6f-43cc-bb88-be40a9f7beda28
104208digoxin 500 MCG in 2 ML InjectionPSN28f2c2cd-e58c-aea2-e063-6394a90a73e71
1042082 ML digoxin 0.25 MG/ML InjectionSCD28f2c2cd-e58c-aea2-e063-6394a90a73e71
104208digoxin 500 MCG per 2 ML InjectionSY28f2c2cd-e58c-aea2-e063-6394a90a73e71

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0781-3059-72007813059722 mL in 1 AMPULE2 mlHistorical
0781-3059-950078130599510 AMPULE in 1 CARTON (0781-3059-95) / 2 mL in 1 AMPULE (0781-3059-72) 10 ampule2003-08-210000-00-00NoNoCurrent