Cosyntropin

Product NDC
0781-3440
Requested package NDC
0781-3440-95
11-digit product format
007813440
Labeler code
0781
Product ID
0781-3440_7e07a53d-7214-4471-859f-059d66318106
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Cosyntropin
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Labeler
Sandoz Inc
Application
ANDA202147
Marketing category
ANDA
Marketing start
2012-06-29
Substance
COSYNTROPIN
Active strength
.25 mg/mL
Pharmacologic classes
Adrenocorticotropic Hormone [CS], Adrenocorticotropic Hormone [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A202147-001COSYNTROPINCOSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A202147-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-2931067a03dcf5…
2025-08-23 18:47 UTC2025-08A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-296a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-2903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-292680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-295bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-2979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-291e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-298072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-295c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-295d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-294b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-2974a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-2987673890dc5c…
2021-03-12 10:30 UTC2021-03A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-295aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-298869cabd3fbd…
2020-11-12 02:37 UTC2020-11A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29c0c555d07b60…
2019-12-14 00:12 UTC2019-12A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-293f01610625f2…
2019-09-15 20:21 UTC2019-09A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29b00525d2431f…
2019-07-19 19:46 UTC2019-07A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-296a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-291c564ffb4f44…
2023-12-20 04:57 UTC2023-12A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-299b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-293f0d92c62455…
2023-05-13 08:27 UTC2023-05A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29053a50430f4f…
2023-01-26 05:58 UTC2023-01A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-293bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-293a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A202147-001COSYNTROPIN0.25MG/VIALINJECTABLE / INJECTIONAP2012-06-29cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A202147-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A202147-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A202147-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A202147-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A202147-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A202147-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A202147-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A202147-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A202147-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A202147-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A202147-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A202147-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A202147-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A202147-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A202147-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A202147-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A202147-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A202147-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A202147-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A202147-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A202147-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A202147-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A202147-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A202147-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A202147-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A202147-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A202147-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A202147-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A202147-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A202147-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A202147-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A202147-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A202147-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A202147-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A202147-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A202147-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A202147-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A202147-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A202147-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A202147-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Cosyntropin
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
COSYNTROPIN.25 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
72YY86EA29Internal UNII lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1342169c-e214-4f22-8363-1fd45b85d1e8Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a62a50ac-1535-4461-9768-8ae703e2e9fbProduct name120210525
270ccf93-a074-eb32-7414-3afc7e6f80eaProduct name120140508
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508
bc07ef78-e82d-0c19-31f4-31f263780582Product name120140508
ef89d5cf-69c1-2a97-8bab-e66260f923c2Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0781-3440-71Cosyntropin1 mL in 1 VIALINJECTION, POWDER, LYOPHILIZED,16
0781-3440-95Cosyntropin10 in 1 CARTONINJECTION, POWDER, LYOPHILIZED,106

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0781-3440-71EA - Each0781-3440cae9d48d-f388-4f22-ab42-52849ed0ab0312013-05-02
0781-3440-95EA - Each0781-34401d5e734a-7aa8-4585-ab85-1b63b772420612013-07-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
COSYNTROPINACTIVE INGREDIENT72YY86EA29COSYNTROPIN INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [SANDOZ INC]1
COSYNTROPINACTIVE MOIETY72YY86EA29COSYNTROPIN INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [SANDOZ INC]1
MANNITOLINACTIVE INGREDIENT3OWL53L36ACOSYNTROPIN INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [SANDOZ INC]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0781-3440COSYNTROPIN INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [SANDOZ INC]5Current NDC, Legacy NDC, 2 package rows20240531_1342169c-e214-4f22-8363-1fd45b85d1e8.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
COSYNTROPINCOSYNTROPINHF Acquisition Co LLC, DBA HealthFirstc6cf2223-4a93-0b28-e053-2a95a90ade532024-02-22Adverse reactionsExact identifier
application applno (ANDA): 202147
application number: ANDA202147
CosyntropinCOSYNTROPINSandoz Inc1342169c-e214-4f22-8363-1fd45b85d1e82024-01-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 202147
application number: ANDA202147
ndc (package): 0781-3440-95
ndc (product): 0781-3440
ndc11 (package): 00781344095
CosyntropinCOSYNTROPINMedical Purchasing Solutions, LLC09441f78-7350-0cb3-e063-6394a90a46ab2023-11-03Adverse reactionsExact identifier
application applno (ANDA): 202147
application number: ANDA202147

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0781-3440-950078134409510 VIAL in 1 CARTON (0781-3440-95) / 1 mL in 1 VIAL (0781-3440-71) 10 vial2012-06-290000-00-00NoNoCurrent