Leuprolide Acetate

Product NDC
0781-4003
11-digit product format
007814003
Labeler code
0781
Product ID
0781-4003_e75789aa-7d4c-4107-b140-b24686874a36
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Leuprolide Acetate
Dosage form
KIT
Labeler
Sandoz Inc
Application
ANDA074728
Marketing category
ANDA
Marketing start
1998-08-04
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A074728-001LEUPROLIDE ACETATELEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-04

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A074728-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-04011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-0431067a03dcf5…
2025-08-23 18:47 UTC2025-08A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-046a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-04fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-04b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-0403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-042680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-045bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-04d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-04d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074728-001LEUPROLIDE ACETATE14MG/2.8ML (1MG/0.2ML)SOLUTION / SUBCUTANEOUSAPRS1998-08-0479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-041e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-048072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-045c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-045d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-044b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-0474a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-0487673890dc5c…
2021-03-12 10:30 UTC2021-03A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-045aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-048869cabd3fbd…
2020-11-12 02:37 UTC2020-11A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04c0c555d07b60…
2019-12-14 00:12 UTC2019-12A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-043f01610625f2…
2019-09-15 20:21 UTC2019-09A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04b00525d2431f…
2019-07-19 19:46 UTC2019-07A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-046a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-041c564ffb4f44…
2023-12-20 04:57 UTC2023-12A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-049b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-043f0d92c62455…
2023-05-13 08:27 UTC2023-05A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04053a50430f4f…
2023-01-26 05:58 UTC2023-01A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-043bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-043a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A074728-001LEUPROLIDE ACETATE1MG/0.2MLINJECTABLE / INJECTIONAPRS1998-08-04cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A074728-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A074728-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A074728-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A074728-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A074728-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A074728-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A074728-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A074728-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A074728-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A074728-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A074728-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A074728-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A074728-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A074728-001AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A074728-001AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A074728-001AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A074728-001AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A074728-001AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A074728-001AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A074728-001AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A074728-001AP187673890dc5c…
2021-03-12 10:30 UTC2021-03A074728-001AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A074728-001AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A074728-001AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A074728-001AP13f01610625f2…
2019-09-15 20:21 UTC2019-09A074728-001AP1b00525d2431f…
2019-07-19 19:46 UTC2019-07A074728-001AP1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A074728-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A074728-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A074728-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A074728-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A074728-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A074728-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A074728-001AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05A074728-001AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01A074728-001AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A074728-001AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A074728-001AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A074728-001AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A074728-001AP1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Leuprolide Acetate
Listing expiration
2027-12-31

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
545835Internal RxNorm lookup
797544Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8bd72c1e-2751-4498-a346-bc5e3acbba0bAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
9e666f57-491f-16e0-fc75-cc1c9f2fe06fProduct name420250515
43944b95-6cc2-4eca-846a-a5e0ed070616Product name120240501
f3ff4518-37fe-47a0-8a1e-6ce032a3efd5Product name120230829
2ed2d111-4d16-4e2a-9b09-7d196056f6c9Product name120211214
ce98e98f-fa6b-48a6-8ad2-9ef8e8098f26Product name120200925
48747306-602a-42cc-957b-5b0c69158eeeProduct name120180604
23ede539-308f-46e5-817b-41ef23af8d40Product name120150930
425e3610-bbe8-4d70-9c46-8cf09afc4e4dProduct name120150930
ae18ed71-8057-40ec-987f-83624e50b906Product name120150122
db5ebcdb-b6ae-21cd-4dc5-76cd84b5578bProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0781-3006-42Leuprolide Acetate2.8 mL in 1 VIAL, MULTI-DOSEINJECTION, SOLUTION2.8 mL1 mg in 0.2mL24
0781-3006-42Leuprolide Acetate1 in 1 CARTONINJECTION, SOLUTION1 mg in 0.2mL24
0781-4003-32Leuprolide Acetate1 in 1 CARTONKIT124

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0781-4003-32EA - Each0781-4003c4afdd50-d7b7-49ee-aa7e-22df90b628cb12013-02-13

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ISOPROPYL ALCOHOLACTIVE INGREDIENTND2M416302LEUPROLIDE ACETATE KIT [SANDOZ INC]13
LEUPROLIDE ACETATEACTIVE INGREDIENT37JNS02E7VLEUPROLIDE ACETATE KIT [SANDOZ INC]13
ISOPROPYL ALCOHOLACTIVE MOIETYND2M416302LEUPROLIDE ACETATE KIT [SANDOZ INC]13
LEUPROLIDEACTIVE MOIETYEFY6W0M8TGLEUPROLIDE ACETATE KIT [SANDOZ INC]13
ACETIC ACIDINACTIVE INGREDIENTQ40Q9N063PLEUPROLIDE ACETATE KIT [SANDOZ INC]13
BENZYL ALCOHOLINACTIVE INGREDIENTLKG8494WBHLEUPROLIDE ACETATE KIT [SANDOZ INC]13
SODIUM CHLORIDEINACTIVE INGREDIENT451W47IQ8XLEUPROLIDE ACETATE KIT [SANDOZ INC]13
SODIUM HYDROXIDEINACTIVE INGREDIENT55X04QC32ILEUPROLIDE ACETATE KIT [SANDOZ INC]13
WATERINACTIVE INGREDIENT059QF0KO0RLEUPROLIDE ACETATE KIT [SANDOZ INC]13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0781-4003LEUPROLIDE ACETATE KIT [SANDOZ INC]21Current NDC, Legacy NDC, 3 package rows20241204_8bd72c1e-2751-4498-a346-bc5e3acbba0b.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Leuprolide AcetateLEUPROLIDE ACETATESandoz Inc8bd72c1e-2751-4498-a346-bc5e3acbba0b2026-05-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 074728
application number: ANDA074728
ndc (product): 0781-4003

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
797544isopropyl alcohol 70 % Medicated PadPSN8bd72c1e-2751-4498-a346-bc5e3acbba0b24
545835leuprolide acetate 1 MG/0.2 ML (5 MG/ML) Injectable SolutionPSN8bd72c1e-2751-4498-a346-bc5e3acbba0b24
797544isopropyl alcohol 0.7 ML/ML Medicated PadSCD8bd72c1e-2751-4498-a346-bc5e3acbba0b24
545835leuprolide acetate 5 MG/ML Injectable SolutionSCD8bd72c1e-2751-4498-a346-bc5e3acbba0b24
797544isopropyl alcohol 70 % Medicated PadSY8bd72c1e-2751-4498-a346-bc5e3acbba0b24
797544isopropyl alcohol 70 % Topical ClothSY8bd72c1e-2751-4498-a346-bc5e3acbba0b24
797544isopropyl alcohol 70 % Topical SwabSY8bd72c1e-2751-4498-a346-bc5e3acbba0b24
545835leuprolide acetate 1 MG per 0.2 ML Injectable SolutionSY8bd72c1e-2751-4498-a346-bc5e3acbba0b24

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0781-3006-42007813006422.8 mL in 1 VIAL, MULTI-DOSE2.8 mlHistorical
0781-4003-32007814003321 KIT in 1 CARTON (0781-4003-32) * 1 VIAL, MULTI-DOSE in 1 CARTON (0781-3006-42) / 2.8 mL in 1 VIAL, MULTI-DOSE * 1 mL in 1 PACKET1 kit1998-08-040000-00-00NoNoCurrent