Entacapone

Product NDC
0781-5578
11-digit product format
007815578
Labeler code
0781
Product ID
0781-5578_a5584d62-a95a-4a17-8c37-0f0bc72b9bb5
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Entacapone
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Sandoz Inc
Application
NDA020796
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
2014-06-04
Substance
ENTACAPONE
Active strength
200 mg/1
Pharmacologic classes
Catechol O-Methyltransferase Inhibitors [MoA], Catechol-O-Methyltransferase Inhibitor [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020796-001COMTANENTACAPONE200MGTABLET / ORALABRLD, RS1999-10-19

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N020796-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-1931067a03dcf5…
2025-08-23 18:47 UTC2025-08N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-196a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-1903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-192680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-195bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-1979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-191e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-198072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-195c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-195d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-194b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-1974a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-1987673890dc5c…
2021-03-12 10:30 UTC2021-03N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-195aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-198869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-193f01610625f2…
2019-09-15 20:21 UTC2019-09N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19b00525d2431f…
2019-07-19 19:46 UTC2019-07N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-196a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-191c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-199b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-193f0d92c62455…
2023-05-13 08:27 UTC2023-05N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19053a50430f4f…
2023-01-26 05:58 UTC2023-01N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-193bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-193a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020796-001COMTAN200MGTABLET / ORALABRLD, RS1999-10-19e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N020796-001AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020796-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020796-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020796-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020796-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020796-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020796-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020796-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020796-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020796-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020796-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020796-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020796-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020796-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020796-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020796-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020796-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020796-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020796-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020796-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020796-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020796-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03N020796-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020796-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020796-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020796-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09N020796-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07N020796-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020796-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020796-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020796-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020796-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020796-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020796-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020796-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05N020796-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01N020796-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020796-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020796-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020796-001AB1e64feba35796…

Additional Listing Data#

Finished product
Yes
Brand name base
Entacapone
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ENTACAPONE200 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
4975G9NM6TInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
317094Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
ad4b6d79-efd3-4c43-b4dc-5afdacf939a4Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
5ce6fab2-d006-4589-8ba0-02cee499cc60Product name220260128
6a098371-84f5-7ced-0ac5-ed90d535b476Product name620220927
a62a50ac-1535-4461-9768-8ae703e2e9fbProduct name120210525
9514609b-a2a9-f8ec-6ba6-3f8e5ee89877Product name120140508
bc07ef78-e82d-0c19-31f4-31f263780582Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0781-5578-01Entacapone100 in 1 BOTTLETABLET, FILM COATED10014

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0781-5578-01EA - Each0781-55789e4f0b35-cb58-4adb-9536-01992fa1cc4812014-07-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ENTACAPONEACTIVE INGREDIENT4975G9NM6TENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
ENTACAPONEACTIVE MOIETY4975G9NM6TENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
CELLULOSE, MICROCRYSTALLINEINACTIVE INGREDIENTOP1R32D61UENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
CROSCARMELLOSE SODIUMINACTIVE INGREDIENTM28OL1HH48ENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
FERRIC OXIDE REDINACTIVE INGREDIENT1K09F3G675ENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
FERRIC OXIDE YELLOWINACTIVE INGREDIENTEX438O2MRTENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
GLYCERININACTIVE INGREDIENTPDC6A3C0OXENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
HYDROGENATED COTTONSEED OILINACTIVE INGREDIENTZ82Y2C65EAENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
HYPROMELLOSESINACTIVE INGREDIENT3NXW29V3WOENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
MAGNESIUM STEARATEINACTIVE INGREDIENT70097M6I30ENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
MANNITOLINACTIVE INGREDIENT3OWL53L36AENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
POLYSORBATE 80INACTIVE INGREDIENT6OZP39ZG8HENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
SUCROSEINACTIVE INGREDIENTC151H8M554ENTACAPONE TABLET, FILM COATED [SANDOZ INC]10
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPENTACAPONE TABLET, FILM COATED [SANDOZ INC]10

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0781-5578ENTACAPONE TABLET, FILM COATED [SANDOZ INC]14Current NDC, Legacy NDC, 1 package rows20241020_ad4b6d79-efd3-4c43-b4dc-5afdacf939a4.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EntacaponeENTACAPONESandoz Incad4b6d79-efd3-4c43-b4dc-5afdacf939a42023-11-30Warnings, Adverse reactionsExact identifier
application applno (NDA): 020796
application number: NDA020796
ndc (product): 0781-5578
EntacaponeENTACAPONEAphena Pharma Solutions - Tennessee, LLC32d30f97-ae0f-4d02-bdd7-75e0783d66bc2019-03-14Warnings, Adverse reactionsExact identifier
application applno (NDA): 020796
application number: NDA020796
EntacaponeENTACAPONESun Pharmaceutical Industries, Inc.205522fb-bb0e-414e-a413-a08bef7276532018-10-25Warnings, Adverse reactionsExact identifier
application applno (NDA): 020796
application number: NDA020796

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
317094entacapone 200 MG Oral TabletPSNad4b6d79-efd3-4c43-b4dc-5afdacf939a414
317094entacapone 200 MG Oral TabletSCDad4b6d79-efd3-4c43-b4dc-5afdacf939a414
317094entacapone 200 MG Oral TabletPSN32d30f97-ae0f-4d02-bdd7-75e0783d66bc1
317094entacapone 200 MG Oral TabletSCD32d30f97-ae0f-4d02-bdd7-75e0783d66bc1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
0781-5578-0100781557801100 TABLET, FILM COATED in 1 BOTTLE (0781-5578-01) 2014-06-040000-00-00NoNoCurrent