Sevoflurane

Product NDC
0781-6160
Requested package NDC
0781-6160-86
11-digit product format
007816160
Labeler code
0781
Product ID
0781-6160_ecf89ead-16b2-91cf-e053-2995a90adc93
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Sevoflurane
Dosage form
LIQUID
Route
RESPIRATORY (INHALATION)
Labeler
Sandoz Inc.
Application
ANDA203793
Marketing category
ANDA
Marketing start
2017-01-25
Substance
SEVOFLURANE
Active strength
250 mL/250mL
Pharmacologic classes
General Anesthesia [PE], General Anesthetic [EPC]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A203793-001SEVOFLURANESEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A203793-001AN

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-0331067a03dcf5…
2025-08-23 18:47 UTC2025-08A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-036a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-0303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-032680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-035bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-0379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-031e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-038072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-035c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-035d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-034b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-0374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-0387673890dc5c…
2021-03-12 10:30 UTC2021-03A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-035aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-038869cabd3fbd…
2020-11-12 02:37 UTC2020-11A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03c0c555d07b60…
2019-12-14 00:12 UTC2019-12A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-033f01610625f2…
2019-09-15 20:21 UTC2019-09A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03b00525d2431f…
2019-07-19 19:46 UTC2019-07A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-036a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-031c564ffb4f44…
2023-12-20 04:57 UTC2023-12A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-039b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-033f0d92c62455…
2023-05-13 08:27 UTC2023-05A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03053a50430f4f…
2023-01-26 05:58 UTC2023-01A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-033bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-033a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A203793-001SEVOFLURANE100%LIQUID / INHALATIONAN2015-11-03cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A203793-001AN1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A203793-001AN131067a03dcf5…
2025-08-23 18:47 UTC2025-08A203793-001AN16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A203793-001AN1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A203793-001AN1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A203793-001AN103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A203793-001AN12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A203793-001AN15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A203793-001AN1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A203793-001AN1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A203793-001AN179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A203793-001AN1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A203793-001AN11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A203793-001AN18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A203793-001AN15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A203793-001AN15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A203793-001AN14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A203793-001AN174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A203793-001AN1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A203793-001AN1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A203793-001AN187673890dc5c…
2021-03-12 10:30 UTC2021-03A203793-001AN15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A203793-001AN18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A203793-001AN1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A203793-001AN13f01610625f2…
2019-09-15 20:21 UTC2019-09A203793-001AN1b00525d2431f…
2019-07-19 19:46 UTC2019-07A203793-001AN1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A203793-001AN16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A203793-001AN11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A203793-001AN1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A203793-001AN1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A203793-001AN19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A203793-001AN1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A203793-001AN13f0d92c62455…
2023-05-13 08:27 UTC2023-05A203793-001AN1053a50430f4f…
2023-01-26 05:58 UTC2023-01A203793-001AN13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A203793-001AN13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A203793-001AN1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A203793-001AN1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A203793-001AN1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Sevoflurane
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
SEVOFLURANE250 mL/250mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
38LVP0K73AInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
200243Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
8604f245-fa99-4092-9042-058aa42e0b74Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
cf7269a1-35c0-eaae-99e6-6fe74a4680f4Product name320250516

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDCEffectiveActionDocumentIndexing SPLRelated label
0781-6160-862021-08-03C16284748780-1c7ccaba7-247e-fd44-e053-dadaa90aa01bSevoflurane USP volatile liquid for inhalation
0781-6160-862021-07-23C16284748780-1c7ccaba7-247e-fd44-e053-dadaa90aa01bSevoflurane USP volatile liquid for inhalation

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0781-6160-43Sevoflurane250 mL in 1 BOTTLE, GLASSLIQUID25015
0781-6160-86Sevoflurane6 in 1 CARTONLIQUID615

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0781-6160-43ML - Milliliter0781-6160628c3280-c778-4eef-9529-eabb6481f0d912017-03-06
0781-6160-86ML - Milliliter0781-6160ef095f7f-fe67-46a0-97df-459da6c558a312017-03-06

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
SEVOFLURANEACTIVE INGREDIENT38LVP0K73ASEVOFLURANE LIQUID [SANDOZ INC.]1
SEVOFLURANEACTIVE MOIETY38LVP0K73ASEVOFLURANE LIQUID [SANDOZ INC.]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0781-6160SEVOFLURANE LIQUID [SANDOZ INC.]15Current NDC, Legacy NDC, 2 package rows20221202_8604f245-fa99-4092-9042-058aa42e0b74.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
SevofluraneSEVOFLURANESandoz Inc.8604f245-fa99-4092-9042-058aa42e0b742022-11-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 203793
application number: ANDA203793
ndc (package): 0781-6160-86
ndc (product): 0781-6160
ndc11 (package): 00781616086

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
200243sevoflurane 100 % Inhalation SolutionPSN8604f245-fa99-4092-9042-058aa42e0b7415
200243sevoflurane 1000 MG/ML Inhalation SolutionSCD8604f245-fa99-4092-9042-058aa42e0b7415
200243sevoflurane 100 % Inhalation SolutionSY8604f245-fa99-4092-9042-058aa42e0b7415

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
0781-6160-86007816160866 BOTTLE, GLASS in 1 CARTON (0781-6160-86) / 250 mL in 1 BOTTLE, GLASS (0781-6160-43) 2017-01-250000-00-00NoNoCurrent