Desflurane

Product NDC: 0781-6172
Requested package NDC: 0781-6172-86
11-digit product format: 007816172
Labeler code: 0781
Product ID: 0781-6172_ecf9968e-58b0-4792-e053-2995a90aef25
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: desflurane
Dosage form: LIQUID
Route: RESPIRATORY (INHALATION)
Labeler: Sandoz Inc.
Application: ANDA208234
Marketing category: ANDA
Marketing start: 2018-02-26
Substance: DESFLURANE
Active strength: 240 mL/240mL
Pharmacologic classes: General Anesthesia [PE], General Anesthetic [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A208234-001	DESFLURANE	DESFLURANE	100%	LIQUID / INHALATION			2018-02-26

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	A208234-001	DESFLURANE	100%	LIQUID / INHALATION	AN	2018-02-26	`cb3db0bc1861…`

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-02-19 14:30 UTC	2026-02	A208234-001	AN	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A208234-001	AN	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A208234-001	AN	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A208234-001	AN	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A208234-001	AN	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A208234-001	AN	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A208234-001	AN	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A208234-001	AN	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A208234-001	AN	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A208234-001	AN	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A208234-001	AN	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A208234-001	AN	1	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A208234-001	AN	1	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A208234-001	AN	1	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A208234-001	AN	1	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A208234-001	AN	1	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A208234-001	AN	1	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A208234-001	AN	1	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A208234-001	AN	1	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	A208234-001	AN	1	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	A208234-001	AN	1	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	A208234-001	AN	1	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	A208234-001	AN	1	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	A208234-001	AN	1	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	A208234-001	AN	1	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	A208234-001	AN	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	A208234-001	AN	1	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	A208234-001	AN	1	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	A208234-001	AN	1	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	A208234-001	AN	1	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	A208234-001	AN	1	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	A208234-001	AN	1	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	A208234-001	AN	1	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	A208234-001	AN	1	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	A208234-001	AN	1	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	A208234-001	AN	1	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	A208234-001	AN	1	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	A208234-001	AN	1	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	A208234-001	AN	1	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	A208234-001	AN	1	`cb3db0bc1861…`

Additional Listing Data#

Finished product: Yes
Brand name base: Desflurane
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
DESFLURANE	240 mL/240mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
CRS35BZ94Q	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
562366	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
21ba0e18-3dbc-4feb-a3a4-f6470c00910a	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
fe60a7eb-08e5-4869-98ba-7cc2b17e8491	Product name	1	20180529

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDC	Effective	Action	Document	Indexing SPL	Related label
0781-6172-86	2021-08-03	C162847	48780-1	c7ccaba7-161d-fd44-e053-dadaa90aa01b	These highlights do not include all the information needed to use DESFLURANE, LIQUID FOR INHALATION safely and effectively. See full prescribing information for DESFLURANE, LIQUID FOR INHALATION. DESFLURANE, liquid for inhalation use Initial U.S. Approval: 1992
0781-6172-86	2021-07-23	C162847	48780-1	c7ccaba7-161d-fd44-e053-dadaa90aa01b	These highlights do not include all the information needed to use DESFLURANE, LIQUID FOR INHALATION safely and effectively. See full prescribing information for DESFLURANE, LIQUID FOR INHALATION. DESFLURANE, liquid for inhalation use Initial U.S. Approval: 1992

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
0781-6172-22	Desflurane	240 mL in 1 BOTTLE, GLASS	LIQUID	240		10
0781-6172-86	Desflurane	6 in 1 CARTON	LIQUID	6		10

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0781-6172-22	ML - Milliliter	0781-6172	f88d9cf6-81f9-43bc-a5d5-a66db31b00f3	1	2019-02-13
0781-6172-86	ML - Milliliter	0781-6172	322366eb-f3aa-4435-b721-c436eea00b69	1	2019-02-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0781-6172	DESFLURANE LIQUID [SANDOZ INC.]	10	Current NDC, Legacy NDC, 2 package rows	20221202_21ba0e18-3dbc-4feb-a3a4-f6470c00910a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Desflurane	DESFLURANE	Sandoz Inc.	21ba0e18-3dbc-4feb-a3a4-f6470c00910a	2022-11-08	Warnings, Adverse reactions	Exact identifier application applno (ANDA): 208234 application number: ANDA208234 ndc (package): 0781-6172-86 ndc (product): 0781-6172 ndc11 (package): 00781617286

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
CRS35BZ94Q	DESFLURANE	57041-67-5	DESFLURANE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
562366	desflurane 100 % Inhalation Solution	PSN	21ba0e18-3dbc-4feb-a3a4-f6470c00910a	10
562366	desflurane 1000 MG/ML Inhalation Solution	SCD	21ba0e18-3dbc-4feb-a3a4-f6470c00910a	10
562366	desflurane 100 % Inhalation Solution	SY	21ba0e18-3dbc-4feb-a3a4-f6470c00910a	10
562366	desflurane 99 % Inhalation Solution	SY	21ba0e18-3dbc-4feb-a3a4-f6470c00910a	10

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0781-6172-86	00781617286	6 BOTTLE, GLASS in 1 CARTON (0781-6172-86) / 240 mL in 1 BOTTLE, GLASS (0781-6172-22)	2018-02-26	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Desflurane - Sandoz Inc. \| Shanghai Hengrui Pharmaceutical Co., Ltd.	Sandoz Inc. \| Shanghai Hengrui Pharmaceutical Co., Ltd.	2022-11-08	HUMAN PRESCRIPTION DRUG LABEL	10