Amantadine Hydrochloride

Product NDC
0832-1015
Requested package NDC
0832-1015-00
11-digit product format
008321015
Labeler code
0832
Product ID
0832-1015_398493aa-8a67-10e2-e063-6394a90aef8d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
amantadine hydrochloride
Dosage form
CAPSULE, GELATIN COATED
Route
ORAL
Labeler
Upsher-Smith Laboratories, LLC
Application
ANDA070589
Marketing category
ANDA
Marketing start
2011-09-15
Marketing end
2026-12-31
Substance
AMANTADINE HYDROCHLORIDE
Active strength
100 mg/1
Pharmacologic classes
Influenza A M2 Protein Inhibitor [EPC], M2 Protein Inhibitors [MoA]
NDC exclude flag
No
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A070589-001AMANTADINE HYDROCHLORIDEAMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A070589-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0587673890dc5c…
2021-03-12 10:30 UTC2021-03A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-055aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-058869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-053f01610625f2…
2019-09-15 20:21 UTC2019-09A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05b00525d2431f…
2019-07-19 19:46 UTC2019-07A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-053f0d92c62455…
2023-05-13 08:27 UTC2023-05A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05053a50430f4f…
2023-01-26 05:58 UTC2023-01A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A070589-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070589-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A070589-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070589-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070589-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070589-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070589-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070589-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070589-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070589-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070589-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070589-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070589-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070589-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070589-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070589-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070589-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070589-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070589-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070589-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070589-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A070589-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070589-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070589-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070589-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A070589-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A070589-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070589-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070589-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070589-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070589-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070589-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070589-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070589-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A070589-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A070589-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070589-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070589-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A070589-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A070589-001AB1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
Amantadine Hydrochloride

Active Ingredients#

Ingredient, Strength table
IngredientStrength
AMANTADINE HYDROCHLORIDE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
M6Q1EO9TD0Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
849389Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5232b933-1df9-43b4-8ac2-61bfa4855e68Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
519d6abc-639d-2962-cced-abbf8b16aad4Product name720250401
82f46845-b4c7-48da-a389-ba5721b956c9Product name220250325
d2c037c0-5ebf-d224-252f-2549922c21c7Product name720240208
b7b57a62-2f7f-1a22-2cb2-eaa5c08d4721Product name220220224
baf7f49c-75b6-496b-a00e-8e766a8e4f03Product name120210127
14e11aaf-885f-472f-a02a-c6a3f28df907Product name120180515
82f46845-b4c7-48da-a389-ba5721b956c9Product name120171103
ebc62596-fc97-4d03-9483-7ba095d25db7Product name120151210
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0832-1015-00Amantadine Hydrochloride100 in 1 BOTTLECAPSULE, GELATIN COATED10019
0832-1015-50Amantadine Hydrochloride500 in 1 BOTTLECAPSULE, GELATIN COATED50019

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0832-1015-00EA - Each0832-1015b4846ddb-7bc6-4d8c-8cd7-654fd0a2d43812012-07-24
0832-1015-50EA - Each0832-1015d5ded1c4-92c9-4c9b-a994-6642449235e212012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
amantadine hydrochlorideACTIVE INGREDIENTM6Q1EO9TD0AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
amantadineACTIVE MOIETYBF4C9Z1J53AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
GELATININACTIVE INGREDIENT2G86QN327LAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
GLYCERININACTIVE INGREDIENTPDC6A3C0OXAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
HYDROGENATED COTTONSEED OILINACTIVE INGREDIENTZ82Y2C65EAAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
HYDROGENATED SOYBEAN OILINACTIVE INGREDIENTA2M91M918CAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
LECITHIN, SOYBEANINACTIVE INGREDIENT1DI56QDM62AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
SOYBEAN OILINACTIVE INGREDIENT241ATL177AAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
WHITE WAXINACTIVE INGREDIENT7G1J5DA97FAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0832-1015AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, LLC]18Current NDC, Legacy NDC, 2 package rows20230524_5232b933-1df9-43b4-8ac2-61bfa4855e68.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Amantadine HydrochlorideAMANTADINE HYDROCHLORIDEUpsher-Smith Laboratories, LLC5232b933-1df9-43b4-8ac2-61bfa4855e682025-07-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070589
application number: ANDA070589
ndc (package): 0832-1015-00
ndc (product): 0832-1015
ndc11 (package): 00832101500

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
849389amantadine HCl 100 MG Oral CapsulePSN5232b933-1df9-43b4-8ac2-61bfa4855e6819
849389amantadine hydrochloride 100 MG Oral CapsuleSCD5232b933-1df9-43b4-8ac2-61bfa4855e6819

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
0832-1015-0000832101500100 CAPSULE, GELATIN COATED in 1 BOTTLE (0832-1015-00) 2011-09-152026-12-31NoNoCurrent