Amantadine Hydrochloride

Product NDC
0832-1015
Requested package NDC
0832-1015-50
11-digit product format
008321015
Labeler code
0832
Product ID
0832-1015_398493aa-8a67-10e2-e063-6394a90aef8d
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
amantadine hydrochloride
Dosage form
CAPSULE, GELATIN COATED
Route
ORAL
Labeler
Upsher-Smith Laboratories, LLC
Application
ANDA070589
Marketing category
ANDA
Marketing start
2011-09-15
Marketing end
2026-12-31
Substance
AMANTADINE HYDROCHLORIDE
Active strength
100 mg/1
Pharmacologic classes
Influenza A M2 Protein Inhibitor [EPC], M2 Protein Inhibitors [MoA]
NDC exclude flag
No
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A070589-001AMANTADINE HYDROCHLORIDEAMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A070589-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0531067a03dcf5…
2025-08-23 18:47 UTC2025-08A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-056a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-052680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-055bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-051e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-058072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-055c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-055d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-054b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-0587673890dc5c…
2021-03-12 10:30 UTC2021-03A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-055aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-058869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-053f01610625f2…
2019-09-15 20:21 UTC2019-09A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05b00525d2431f…
2019-07-19 19:46 UTC2019-07A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-056a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-051c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-059b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-053f0d92c62455…
2023-05-13 08:27 UTC2023-05A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05053a50430f4f…
2023-01-26 05:58 UTC2023-01A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-053bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-053a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A070589-001AMANTADINE HYDROCHLORIDE100MGCAPSULE / ORALAB1986-08-05cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A070589-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A070589-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A070589-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A070589-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A070589-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A070589-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A070589-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A070589-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A070589-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A070589-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A070589-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A070589-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A070589-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A070589-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A070589-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A070589-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A070589-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A070589-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A070589-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A070589-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A070589-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A070589-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A070589-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A070589-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A070589-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A070589-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A070589-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A070589-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A070589-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A070589-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A070589-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A070589-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A070589-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A070589-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A070589-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A070589-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A070589-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A070589-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A070589-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A070589-001AB1cb3db0bc1861…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Amantadine HydrochlorideAMANTADINE HYDROCHLORIDEUpsher-Smith Laboratories, LLC5232b933-1df9-43b4-8ac2-61bfa4855e682025-07-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 070589
application number: ANDA070589
ndc (package): 0832-1015-50
ndc (product): 0832-1015
ndc11 (package): 00832101550

Additional Listing Data#

Finished product
Yes
Brand name base
Amantadine Hydrochloride

Active Ingredients#

Ingredient, Strength table
IngredientStrength
AMANTADINE HYDROCHLORIDE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
M6Q1EO9TD0Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
849389Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
5232b933-1df9-43b4-8ac2-61bfa4855e68Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
519d6abc-639d-2962-cced-abbf8b16aad4Product name720250401
82f46845-b4c7-48da-a389-ba5721b956c9Product name220250325
d2c037c0-5ebf-d224-252f-2549922c21c7Product name720240208
b7b57a62-2f7f-1a22-2cb2-eaa5c08d4721Product name220220224
baf7f49c-75b6-496b-a00e-8e766a8e4f03Product name120210127
14e11aaf-885f-472f-a02a-c6a3f28df907Product name120180515
82f46845-b4c7-48da-a389-ba5721b956c9Product name120171103
ebc62596-fc97-4d03-9483-7ba095d25db7Product name120151210
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0832-1015-00Amantadine Hydrochloride100 in 1 BOTTLECAPSULE, GELATIN COATED10019
0832-1015-50Amantadine Hydrochloride500 in 1 BOTTLECAPSULE, GELATIN COATED50019

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0832-1015-00EA - Each0832-1015b4846ddb-7bc6-4d8c-8cd7-654fd0a2d43812012-07-24
0832-1015-50EA - Each0832-1015d5ded1c4-92c9-4c9b-a994-6642449235e212012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
amantadine hydrochlorideACTIVE INGREDIENTM6Q1EO9TD0AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
amantadineACTIVE MOIETYBF4C9Z1J53AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
D&C YELLOW NO. 10INACTIVE INGREDIENT35SW5USQ3GAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
GELATININACTIVE INGREDIENT2G86QN327LAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
GLYCERININACTIVE INGREDIENTPDC6A3C0OXAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
HYDROGENATED COTTONSEED OILINACTIVE INGREDIENTZ82Y2C65EAAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
HYDROGENATED SOYBEAN OILINACTIVE INGREDIENTA2M91M918CAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
LECITHIN, SOYBEANINACTIVE INGREDIENT1DI56QDM62AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
SOYBEAN OILINACTIVE INGREDIENT241ATL177AAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
TITANIUM DIOXIDEINACTIVE INGREDIENT15FIX9V2JPAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12
WHITE WAXINACTIVE INGREDIENT7G1J5DA97FAMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, INC]12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0832-1015AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [UPSHER-SMITH LABORATORIES, LLC]18Current NDC, Legacy NDC, 2 package rows20230524_5232b933-1df9-43b4-8ac2-61bfa4855e68.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
849389amantadine HCl 100 MG Oral CapsulePSN5232b933-1df9-43b4-8ac2-61bfa4855e6819
849389amantadine hydrochloride 100 MG Oral CapsuleSCD5232b933-1df9-43b4-8ac2-61bfa4855e6819

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
0832-1015-5000832101550500 CAPSULE, GELATIN COATED in 1 BOTTLE (0832-1015-50) 2011-09-152026-12-31NoNoCurrent