Amantadine Hydrochloride

Product NDC
10135-692
11-digit product format
101350692
Labeler code
10135
Product ID
10135-692_3e752827-026e-d525-e063-6394a90a7e80
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Amantadine Hydrochloride
Dosage form
TABLET
Route
ORAL
Labeler
Marlex Pharmaceuticals Inc
Application
ANDA210215
Marketing category
ANDA
Marketing start
2020-03-01
Substance
AMANTADINE HYDROCHLORIDE
Active strength
100 mg/1
Pharmacologic classes
Influenza A M2 Protein Inhibitor [EPC], M2 Protein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A210215-001AMANTADINE HYDROCHLORIDEAMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A210215-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-1031067a03dcf5…
2025-08-23 18:47 UTC2025-08A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-106a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-1003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-102680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-105bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-1079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-101e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-108072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-105c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-105d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-104b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-1087673890dc5c…
2021-03-12 10:30 UTC2021-03A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-105aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-108869cabd3fbd…
2020-11-12 02:37 UTC2020-11A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-106a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-101c564ffb4f44…
2023-12-20 04:57 UTC2023-12A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-109b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-103f0d92c62455…
2023-05-13 08:27 UTC2023-05A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10053a50430f4f…
2023-01-26 05:58 UTC2023-01A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-103bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-103a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A210215-001AMANTADINE HYDROCHLORIDE100MGTABLET / ORALAB2020-03-10a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A210215-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A210215-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A210215-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A210215-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A210215-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A210215-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A210215-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A210215-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A210215-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A210215-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A210215-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A210215-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A210215-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A210215-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A210215-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A210215-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A210215-001AB14b0b4de00fa7…
2022-03-09 01:35 UTC2022-03A210215-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A210215-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A210215-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A210215-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A210215-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A210215-001AB1c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A210215-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A210215-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A210215-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A210215-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A210215-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A210215-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A210215-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A210215-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A210215-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A210215-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A210215-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A210215-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A210215-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A210215-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Amantadine Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
AMANTADINE HYDROCHLORIDE100 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
M6Q1EO9TD0Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
849389Internal RxNorm lookup
849395Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
25af52ee-9b29-4c07-a383-62d4537b63e0Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
519d6abc-639d-2962-cced-abbf8b16aad4Product name720250401
82f46845-b4c7-48da-a389-ba5721b956c9Product name220250325
d2c037c0-5ebf-d224-252f-2549922c21c7Product name720240208
b7b57a62-2f7f-1a22-2cb2-eaa5c08d4721Product name220220224
14e11aaf-885f-472f-a02a-c6a3f28df907Product name120180515
82f46845-b4c7-48da-a389-ba5721b956c9Product name120171103

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
10135-692-01Amantadine Hydrochloride100 in 1 BOTTLETABLET1008
10135-692-05Amantadine Hydrochloride500 in 1 BOTTLETABLET5008

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
10135-692-01EA - Each10135-692e5a10d28-e2f3-4eb1-8bf3-7433f2348ea112020-04-20
10135-692-05EA - Each10135-6921ef0ee4a-828d-4b58-bedd-4c1d3a8695dd12020-04-20

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
10135-692AMANTADINE HYDROCHLORIDE TABLET AMANTADINE HYDROCHLORIDE CAPSULE, GELATIN COATED [MARLEX PHARMACEUTICALS INC]7Current NDC, Legacy NDC, 2 package rows20241025_25af52ee-9b29-4c07-a383-62d4537b63e0.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Amantadine HydrochlorideAMANTADINE HYDROCHLORIDEMarlex Pharmaceuticals Inc25af52ee-9b29-4c07-a383-62d4537b63e02025-09-10Warnings, Adverse reactionsExact identifier
application applno (ANDA): 210215
application number: ANDA210215
ndc (product): 10135-692

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
849389amantadine HCl 100 MG Oral CapsulePSN25af52ee-9b29-4c07-a383-62d4537b63e08
849395amantadine HCl 100 MG Oral TabletPSN25af52ee-9b29-4c07-a383-62d4537b63e08
849389amantadine hydrochloride 100 MG Oral CapsuleSCD25af52ee-9b29-4c07-a383-62d4537b63e08
849395amantadine hydrochloride 100 MG Oral TabletSCD25af52ee-9b29-4c07-a383-62d4537b63e08

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
10135-692-0110135069201100 TABLET in 1 BOTTLE (10135-692-01) 100 tablet2020-03-010000-00-00NoNoCurrent
10135-692-0510135069205500 TABLET in 1 BOTTLE (10135-692-05) 500 tablet2020-03-010000-00-00NoNoCurrent